Narrative review discusses perioperative local anesthetics and regional anesthesia in cancer care
Local Anesthetics May Slow Cancer Spread
This narrative review examines the role of perioperative local anesthetics and regional anesthesia compared to opioids within comprehensive …
Using local anesthesia instead of just opioids during surgery might help stop cancer from spreading after the operation.
Narrative review contrasts pediatric and adult pain management in emergency settings
ER Doctors Are Rethinking Pain Care for Kids vs Adults
This narrative review synthesizes global emergency department pain management strategies for pediatric versus adult patients. It highlights …
It starts with a child clutching a broken arm.
In a cohort of 561 individuals with chronic pain, sex and gender identity influenced repeated prescription refill odds.
Your Pain Meds May Depend on Who You Are, Not Just What Hurts
This observational cohort study examined 561 individuals living with chronic pain using public and private prescription claims data over one…
Chronic pain treatment isn’t one-size-fits-all; new research shows your personal identity plays a major role in the prescriptions you receiv…
Systematic Review Analyzes Pharmacometric Modeling of Opioids and Fentanyl in Pregnancy
Opioid Dosing in Pregnancy May Need a Rethink
This systematic review evaluates pharmacometric modeling approaches, including population pharmacokinetic and physiologically based pharmaco…
Pregnancy speeds up how the body processes pain meds, meaning standard doses may leave moms in pain or risk baby safety.
Report estimates state-level economic costs of opioid use disorder and fatal overdose
Report estimates state-level economic costs of opioid use disorder and overdose
A report estimated state-level economic costs of opioid use disorder and fatal opioid overdose in the United States. Specific numerical find…
A new report estimates the economic costs of opioid use disorder and fatal overdoses for every state in the United States in 2017.
Case series identifies 38 medetomidine-involved opioid overdoses in Chicago
Chicago health officials identify overdoses involving veterinary sedative mixed with opioids
A case series in Chicago identified 38 individuals with medetomidine-involved opioid overdoses (12 confirmed, 26 probable). This descriptive…
Chicago officials warn that a veterinary sedative is now mixed with opioids in street drugs, causing 38 overdoses in the city.
Carbamazepine linked to lower postoperative pain scores in tentorial meningioma resection
Could an old seizure drug help people recover from brain surgery with less pain?
A retrospective cohort study of 42 patients undergoing tentorial meningioma resection found those receiving postoperative carbamazepine (200…
An old seizure drug helped brain surgery patients report significantly less pain two and seven days after their operation compared to standa…
National trends show rising Hepatitis C and opioid use disorder rates in pregnant women at delivery
Study finds rising Hepatitis C and opioid disorder rates among pregnant women in the U.S.
An observational study of pregnant women at delivery hospitalization in the United States from 2000-2015 found significant increases in both…
Hepatitis C and opioid use disorder rates rose significantly among U.S. pregnant women delivering in hospitals between 2000 and 2015.
Multimodal analgesia linked to lower opioid use and pain scores after endometrial cancer surgery
Study finds certain pain management approaches linked to less opioid use after endometrial cancer surgery
A retrospective cohort study of 650 women undergoing endometrial cancer surgery found that multimodal or regional-based analgesic regimens w…
Women receiving combined pain relief after endometrial cancer surgery reported lower pain scores and used fewer opioids on the first day com…
Intranasal ketamine shows similar pain relief to IV opioids for renal colic in ED meta-analysis
Intranasal ketamine and IV opioids show similar pain relief for kidney stones
A meta-analysis of 4 RCTs including 454 patients with renal colic found no significant differences in pain scores at 5, 15, or 30 minutes be…
Nasal ketamine and IV opioids provide equal pain relief for kidney stones, with no difference in side effects or need for extra medication.