Transthyretin stabilizers and RNA-silencing therapies attenuate cardiac remodeling in transthyretin amyloid cardiomyopathy
New Therapies May Slow Heart Damage in Amyloid Cardiomyopathy
This meta-analysis of 3646 adults with cardiac amyloidosis found that transthyretin stabilizers and RNA-silencing therapies are associated w…
Specific drug therapies may help stabilize heart structure and slow the progression of damage for adults with transthyretin amyloid cardiomy…
Deep learning model screens for transthyretin amyloid cardiomyopathy using ECG images
AI spots hidden heart disease from routine ECGs
This observational study developed a deep learning model to identify transthyretin amyloid cardiomyopathy from ECG images.
A new AI tool finds signs of a dangerous heart disease in routine ECGs years before symptoms worsen, offering hope for earlier treatment in …
Acoramidis associated with lower diuretic intensification in transthyretin amyloid cardiomyopathy
New Heart Drug Shows Lower Risk of Hospitalization vs Older Option
In this retrospective cohort study using US claims data, acoramidis was associated with a lower risk of diuretic intensification and a compo…
A new heart drug cut diuretic needs and hospitalizations more than the older option in early real-world use.
AI-assisted echocardiography shows moderate agreement with cardiologists in ATTR-CM monitoring
AI Ultrasounds Match Experts for Tracking a Stealth Heart Disease
This retrospective observational study evaluated a fully automated, AI-assisted echocardiographic algorithm (Us2.ai) against human readers i…
AI heart scans match expert doctors for tracking a silent protein buildup, offering reliable monitoring for patients with a common form of h…
AI-derived echocardiographic measurements predict outcomes in transthyretin cardiomyopathy patients
AI Echo Scan Predicts Heart Failure Risk
This retrospective study evaluated 347 patients from two ATTR-CM registries to assess the prognostic value of AI-derived echocardiographic m…
A new computer program can spot warning signs of heart trouble in ATTR-CM patients better than current methods alone.
SGLT2 inhibitors associated with lower mortality in ATTR-CM patients receiving disease-modifying therapy
Could a common diabetes drug help people with a serious heart condition live longer?
A meta-analysis of 7 observational studies including 7,283 patients with ATTR cardiomyopathy found SGLT2 inhibitor use was associated with l…
A common diabetes drug linked to lower death risk and fewer heart attacks for people with a serious heart condition called transthyretin amy…
Research across Cardiomyopathy
Related studies from across the Cardiomyopathy family.
Cardiac myosin inhibitors improve exercise capacity and health status in patients with hypertrophic cardiomyopathy
New heart medication shows promise for hypertrophic cardiomyopathy patients
This meta-analysis evaluated the impact of cardiac myosin inhibitors on adults with symptomatic non-obstructive hypertrophic cardiomyopathy.…
A new class of heart drugs may improve exercise capacity and quality of life for people with a specific heart muscle condition.
AI-empowered echocardiography shows promise for HCM diagnosis and risk prediction, but validation is lacking
AI Echocardiography Shows Promise for Heart Condition
This systematic review synthesizes AI-empowered echocardiography applications in hypertrophic cardiomyopathy, categorizing methods by comple…
AI-powered echocardiography may improve diagnosis and risk prediction for hypertrophic cardiomyopathy, but large-scale validation is still n…
Gene, inflammation, and metabolic dysregulation drive pathophysiology in pediatric dilated cardiomyopathy
Gene, Inflammation, Metabolism Link in Child Heart Failure
This systematic review examines the role of the gene-inflammation-metabolism axis in pediatric dilated cardiomyopathy. The authors identify …
A new review links genes, inflammation, and metabolism in pediatric dilated cardiomyopathy, offering a roadmap for targeted treatments.
Supraventricular tachyarrhythmias occur more frequently in patients with Arrhythmogenic Cardiomyopathy and Brugada Syndrome
Heart conditions like Brugada syndrome increase risk of rapid heartbeats
This systematic review of 30 studies indicates that supraventricular tachyarrhythmias (SVT) are more frequent in patients with Arrhythmogeni…
Patients with certain heart conditions face a higher risk of fast heartbeats, which can lead to complications like heart failure or unnecess…
Exercise improves cardiorespiratory fitness and quality of life in patients with hypertrophic cardiomyopathy
Exercise improves heart health and fitness for HCM patients
This meta-analysis of 9,702 patients with hypertrophic cardiomyopathy (HCM) found that exercise is associated with increased peak oxygen con…
New research shows that structured exercise can improve heart fitness, body weight, and quality of life for people with hypertrophic cardiom…
Global Longitudinal Strain as a Potential Predictor of Sudden Cardiac Death in Hypertrophic Cardiomyopathy
Heart imaging helps identify high risk in cardiomyopathy patients
Meta-analysis suggests reduced global longitudinal strain identifies high-risk patients with hypertrophic cardiomyopathy prone to fatal arrh…
A new way to measure heart muscle movement may help doctors identify which patients with a specific heart condition are at higher risk for s…
Vascular smooth muscle cell immune interactions drive remodeling across cardiovascular diseases
How blood vessel cells drive heart disease and high blood pressure
This narrative review synthesizes mechanisms of VSMC-immune interactions in atherosclerosis, hypertension, aortic aneurysms, and arteritis. …
A new review reveals how blood vessel cells change in heart disease, high blood pressure, and more.
Review of Diabetic Cardiomyopathy without reported trial data or specific outcomes
Review of Diabetic Cardiomyopathy offers new understanding of this heart condition
This narrative review addresses Diabetic cardiomyopathy but reports no specific population, sample size, or intervention details. The author…
This review looks at diabetic cardiomyopathy to help doctors understand this specific heart problem better for patients with diabetes.
Mini review examines sudden cardiac death risks in marathon runners across different age groups
Marathon running links to higher heart risk in older men and full-distance participants
This mini review synthesizes evidence on sudden cardiac death (SCD) and coronary artery disease in marathon runners. The authors note that r…
A review of marathon runners shows heart risks vary by age, sex, and race distance, with most events happening near the finish.
Narrative review discusses Ganoderma lucidum polysaccharides for diabetes and related complications
New research shows mushroom compounds may help control blood sugar and fix organ damage
This narrative review examines the theoretical potential of Ganoderma lucidum polysaccharides (GLPs) for diabetes and associated conditions.
A common mushroom extract could help lower blood sugar and heal organ damage for millions of people with diabetes
Systematic review and meta-analysis of MYH7 versus MYBPC3 variants in obstructive hypertrophic cardiomyopathy
Specific heart genes predict different risks for HCM patients
This systematic review and meta-analysis pooled data from 192,361 participants in cohort or registry studies to compare MYH7 and MYBPC3 vari…
New data shows specific heart genes predict different risks for people with obstructive hypertrophic cardiomyopathy and guide care plans.
PSI-QPI metrics improved prediction of TTN-TV disease penetrance and expressivity in cardiomyopathy patients
New Tool Predicts Heart Failure Risk in Genetic Heart Disease
This cohort study evaluated PSI-DCM-LR-15, QPI, and PSI-QPI metrics in patients with cardiomyopathy due to TTN-TV and cardiac tissue from or…
A new combination of tests can more accurately predict which patients with genetic heart muscle disease will develop serious heart failure.
Questions about Transthyretin cardiomyopathy
Do SGLT2 inhibitors lower mortality rates in patients with transthyretin cardiomyopathy?
SGLT2 inhibitors may lower all-cause mortality in transthyretin cardiomyopathy, but evidence is mixed; one study shows benefit, another shows no mortality reduction when added to tafamidis.
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