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Venous thrombosis

Part of Embolism and Thrombosis

0 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for venous thrombosis

35 trials tracked for venous thrombosis: 14 in phase 3 or 4 and 3 with published results. The most-cited published study has 790 citations.

35Trials tracked
14Phase 3 & 4
0Recruiting
3With published results
Phase distribution
Phase 4 1 Phase 3 13 Phase 2 5 Phase 1 1 Other / NA 15
  1. Phase 3 Reduced-dosed Rivaroxaban in the Long-term Prevention of Recurrent Symptomatic VTE(Venous Thromboembolism) Completed · 790 cited
  2. Phase 3 Evaluation of the Duration of Therapy for Thrombosis in Children Completed · 101 cited
  3. Phase 3 Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis Completed · 87 cited
  4. Phase 4 Study to Evaluate Weight-based Enoxaparin Dosing in Obese Medical Patients at Risk for DVT Completed
  5. Phase 3 Total Hip Replacement Study Of GSK576428 (Fondaparinux Sodium) Completed
  6. Phase 3 The Treatment of Acute Deep Vein Thrombosis (DVT) of GSK576428 (Fondaparinux Sodium) in Japanese Patients Completed
Show 29 more trials
  1. Phase 3 Prophylactic Enoxaparin Dosing for Prevention of Venous Thromboembolism in Pregnancy. Completed
  2. Phase 3 Comparative Investigation of Low Molecular Weight (LMW) Heparin/Edoxaban Tosylate (DU176b) Versus (LMW) Heparin/Warfarin in the Treatment of Symptomatic Deep-Vein Blood Clots and/or Lung Blood Clots. (The Edoxaban Hokusai-VTE Study). Completed
  3. Phase 3 Efficacy and Safety Study of Apixaban for Extended Treatment of Deep Vein Thrombosis or Pulmonary Embolism Completed
  4. Phase 3 Evaluation Of Fondaparinux (Also Called ARIXTRA) 2.5 mg Subcutaneously Once Daily For The Treatment Of Superficial Thrombophlebitis (Also Known As Superficial Vein Thrombosis) Completed
  5. Phase 3 Efficacy and Safety Study of Apixaban for the Treatment of Deep Vein Thrombosis or Pulmonary Embolism Completed
  6. Phase 3 Oral Direct Factor Xa Inhibitor Rivaroxaban in Patients With Acute Symptomatic Deep Vein Thrombosis - The EINSTEIN DVT Study Completed
  7. Phase 3 A Study to Evaluate the Efficacy and Safety of Fondaparinux for the Prevention of Venous Blood Clots in Patients With a Plaster Cast or Other Type of Immobilization for a Below-knee Injury Not Needing Surgery Completed
  8. Phase 3 Study of Apixaban for the Prevention of Thrombosis-related Events in Patients With Acute Medical Illness Completed
  9. Phase 2 A Randomized, Open-Label, Parallel-Group, Multi-Center Study for the Evaluation of Efficacy and Safety of Edoxaban Monotherapy Versus Low Molecular Weight (LMW) Heparin/Warfarin in Subjects With Symptomatic Deep-Vein Thrombosis Completed
  10. Phase 2 Prolongation of the Interval Between Monitoring of Warfarin in Stable Patients Completed
  11. Phase 2 Oral Rivaroxaban in Children With Venous Thrombosis Completed
  12. Phase 2 Deep Vein Thrombosis Treatment With the Oral Direct Factor Xa Inhibitor Rivaroxaban in Patients Using a Strong CYP 3A4 Inducer Completed
  13. Phase 2 A Study of BIBR 1048 in Prevention of Venous Thromboembolism in Patients With TKR Surgery. Completed
  14. Phase 1 Switching Study From Warfarin to Rivaroxaban Completed
  15. N/A Registry of AngioJet Use in the Peripheral Vascular System Completed
  16. N/A Educating Nurses About Venous Thromboembolism (VTE) Prevention Completed
  17. N/A Peripherally Inserted Central Catheter (PICC) Thrombosis: Reverse Taper Versus Non-tapered Catheters Completed
  18. N/A Compression Treatment Effects on Complications and Healing of Achilles Tendon Rupture Completed
  19. N/A Hemorrhage Risk Prescribed Arixtra Completed
  20. N/A Tranexamic Acid and Blood Clots in Knee Surgery Completed
  21. N/A Study Of Lybrel In Relation To Venous Thromboembolism Completed
  22. N/A Post-thrombotic Syndrome & Predictors of Recurrence in Catheter-related Thrombosis Completed
  23. N/A A Prospective Observational Registry of Peripheral Use of AngioJet Rheolytic Thrombectomy With Mid-Length Catheters Completed
  24. N/A JETi Lower Extremity Venous Thrombosis Completed
  25. N/A A Preliminary Clinical Usability Study for the Recovery Force DVT II Cuff Completed
  26. N/A Intermittent Pneumatic Compression in Surgical Patients at Extremely-high Risk for Venous Thromboembolism Completed
  27. N/A Using Intravenous Heparin Versus Standard of Care Subcutaneous Heparin to Prevent Clots After Surgery Completed
  28. N/A Vasculaire Compression System Increases Flow Velocity in the Femoral Vein Completed
  29. N/A Comparison of Different Intermittent Pneumatic Compression Devices for Deep Vein Thrombosis Completed

Showing the 35 most-cited and recently-updated of 35 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found Updated — new results For clinicians

Venous thrombosis: what the trials found

Several anticoagulant agents have demonstrated efficacy in managing venous thromboembolism (VTE). Rivaroxaban significantly reduced the incidence of symptomatic recurrent VTE compared to other treatments 12 and showed a reduction in the composite of recurrent DVT, non-fatal PE, and all-cause mortality 12. BAY 59-7939 also demonstrated significant reductions in the composite of fatal or non-fatal symptomatic recurrent VTE 3, as well as in the composite of primary efficacy outcomes including myocardial infarction, ischemic stroke, or systemic non-CNS embolism 3.

Fondaparinux has shown consistent results in reducing VTE events and mortality [13, 14] and demonstrated a 0% rate of recurrent or new symptomatic VTE in specific cohorts 15. Edoxaban tosylate was associated with significantly lower rates of clinically relevant bleeding compared to other treatments 7, while Apixaban showed significant reductions in the composite of symptomatic recurrent VTE or all-cause death 10. Enoxaparin also demonstrated a statistically significant reduction in the incidence of adjudicated composite symptomatic, recurrent VTE or VTE-related death 9.

recent-not-corroborated":["JETi for lower extremity venous thrombosis showed an 84.5% success rate for $\geq$75% thrombus reduction with a 1.7% rate of major adverse events within 30 days 1."],

For the clinician treating this condition

  • Rivaroxaban and BAY 59-7939 are established options for reducing symptomatic recurrent VTE and associated mortality [3, 12].
  • Fondaparinux and Enoxaparin have demonstrated significant efficacy in preventing VTE and related deaths [9, 13, 14].
  • Edoxaban tosylate is associated with a lower incidence of clinically relevant bleeding compared to alternative treatments 7.

AI synthesis of 7 cited trials, updated Jun 20, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
No published articles yet for this condition. Check back soon.

Research across Embolism and Thrombosis

Related studies from across the Embolism and Thrombosis family.

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AI-guided ultrasound achieves 92.86% sensitivity for DVT triage, avoids 35.32% of standard scans
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DOACs reduce thrombosis recurrence and major bleeding compared to warfarin in morbidly obese VTE patients
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Evaluating Enoxaparin Dosing Strategies for Venous Thromboembolism Prophylaxis in Bariatric Surgery Patients
Diabetes & Endocrinology Meta-analysis
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A meta-analysis of 1,276 patients indicates that while 60 mg enoxaparin achieves higher anti-factor Xa levels, clinical outcomes remain simi…
A review of 1,276 patients shows that higher doses of the blood thinner enoxaparin do not improve safety or results for those undergoing wei…
Direct oral anticoagulants reduce thrombotic events and major bleeding in cirrhosis with atrial fibrillation or venous thromboembolism
Cardiology Meta-analysis
Direct oral anticoagulants reduce thrombotic events and major bleeding in cirrhosis with atrial fibrillation or venous thromboembolism Direct oral anticoagulants show promise for patients with liver cirrhosis
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D-dimer shows moderate diagnostic potential for ruling out deep vein thrombosis after total joint arthroplasty
Emergency Medicine Meta-analysis
D-dimer shows moderate diagnostic potential for ruling out deep vein thrombosis after total joint arthroplasty D-dimer test helps rule out dangerous blood clots after joint replacement
This meta-analysis of 7,123 patients evaluated the diagnostic performance of D-dimer for screening deep vein thrombosis following total join…
A new analysis of over 7,000 patients finds D-dimer blood test is moderately useful for ruling out deep vein thrombosis after hip or knee re…
Ankle pump exercises plus anticoagulants reduce postoperative DVT risk
Neurology Meta-analysis
Ankle pump exercises plus anticoagulants reduce postoperative DVT risk Ankle Pump Exercises May Lower DVT Risk After Surgery
This meta-analysis found that adding ankle pump exercises to anticoagulant therapy significantly reduced the risk of postoperative deep vein…
Adding ankle pump exercises to standard blood thinner therapy may significantly lower the risk of dangerous blood clots after surgery.
Endovascular therapy reduces post-thrombotic syndrome severity by 2.0 points compared to standard care
Radiology & Imaging RCT
Endovascular therapy reduces post-thrombotic syndrome severity by 2.0 points compared to standard care Endovascular Therapy Improves Quality of Life for Post-Thrombotic Syndrome
This randomized controlled trial of 225 patients with moderate or severe post-thrombotic syndrome and iliac-vein obstruction found that endo…
A new trial shows that endovascular therapy can reduce the severity of post-thrombotic syndrome and improve daily quality of life.
LMWH remains useful when oral anticoagulants are difficult to use safely in venous thromboembolism patients
Drug Pipeline Sys. Review
LMWH remains useful when oral anticoagulants are difficult to use safely in venous thromboembolism patients Low-molecular-weight heparin remains useful when oral anticoagulants are difficult to use safely
This narrative review examines low-molecular-weight heparin dosing, anti-factor Xa monitoring, treatment interruption, and switching strateg…
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Systematic review and meta-analysis of machine learning models for deep vein thrombosis prediction in hospitalized adults
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Systematic review and meta-analysis of machine learning models for deep vein thrombosis prediction in hospitalized adults Machine learning models predict blood clots in hospitalized adults with high accuracy
This systematic review and meta-analysis synthesized evidence on machine learning-based prediction models for deep vein thrombosis in hospit…
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Pre-infection vaccination linked to lower cardiovascular and cerebrovascular event risks in SARS-CoV-2 infected individuals
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