CGRP-targeted therapies provide clinically meaningful improvements in vertigo frequency and patient-reported quality of life
New CGRP therapies show promise for vestibular migraine relief
This systematic review evaluates the efficacy of conventional pharmacological treatments and CGRP-targeted therapies for vestibular migraine…
Newer CGRP-targeted treatments may offer significant relief for those struggling with the dizzy spells and headaches of vestibular migraine.
Microglia and astrocyte crosstalk serves as a key mediator of central sensitization in vestibular migraine
Brain cells may drive the pain of vestibular migraines
This systematic review explores the role of neuroimmune interactions in the pathophysiology of vestibular migraine. The authors identify bid…
New research highlights how specific brain cells communicate to cause chronic pain, offering a path to better treatments for vestibular migr…
Cerebellum functions as a modulatory component in migraine networks rather than a primary attack generator
CGRP Treatment Shows Changes in Migraine Related Brain Networks
This narrative review synthesizes imaging and structural data regarding the role of the cerebellum in migraine and related conditions. The a…
New imaging shows that CGRP treatments may affect the cerebellum, a part of the brain involved in migraine networks and balance.
Five anchor clinical phenotypes provide a framework for individualized management of persistent postural-perceptual dizziness
New framework helps doctors treat persistent postural-perceptual dizziness
This narrative review synthesizes a proposed framework to manage persistent postural-perceptual dizziness (PPPD) by categorizing patients in…
A new clinical framework identifies five distinct types of chronic dizziness to help doctors create personalized treatment plans for patient…
Neurotological evaluation distinguishes vestibular migraine from viral neuritis in acute unilateral vestibulopathy
A single case report shows rapid recovery in vestibular migraine
This case report describes a 40-year-old woman with a history of migraine with aura presenting to the emergency department with vestibular m…
A 40-year-old woman with vestibular migraine recovered her balance quickly. This case suggests that specific reflex patterns help doctors te…
Narrative review explores fMRI utility in otolaryngology disorders including tinnitus and vestibular migraine
The Brain Scan Changing How Doctors See Hearing and Balance Problems
This narrative review examines the application of functional magnetic resonance imaging (fMRI) in patients with otolaryngology–head and neck…
A new brain scan shows that tinnitus and hearing loss aren't just ear problems, but actually change how the brain works.
Research across Migraine
Related studies from across the Migraine family.
Migraine-associated forehead erythema may resolve rapidly with standard acute analgesic treatment
A rare skin condition linked to migraine attacks in one man
This case report and review of literature describes a patient with migraine and red forehead dot syndrome. The report notes that headache an…
A man with migraines experienced a red forehead dot that improved quickly with standard pain medicine, highlighting a rare skin-headache lin…
OnabotulinumtoxinA remains the most established procedural intervention for chronic migraine prevention
OnabotulinumtoxinA Shows Most Established Evidence for Chronic Migraine Prevention
This umbrella review synthesizes evidence for various procedural interventions in chronic migraine, identifying onabotulinumtoxinA as the mo…
OnabotulinumtoxinA has the clearest evidence for chronic migraine prevention, while other procedures like nerve blocks and acupuncture show …
Auriculotherapy Shows Consistent Pain Relief Across Multiple Conditions
Auriculotherapy May Help Manage Chronic Back Pain and Migraines
A systematic review finds auriculotherapy reduces pain intensity and analgesic needs across acute and chronic pain conditions, with mild sid…
Auriculotherapy shows potential as a safe, non-drug way to reduce pain for patients dealing with migraines, back pain, and cancer pain.
Transcutaneous auricular vagus nerve stimulation shows potential for depression, epilepsy, migraine, and post-stroke rehabilitation
Vagus Nerve Stimulation Shows Potential for Depression and Migraine
This narrative review of 72 articles explores the mechanism and therapeutic potential of transcutaneous auricular vagus nerve stimulation (t…
A new method of nerve stimulation may offer potential benefits for managing conditions like migraine, epilepsy, and depression.
Probiotics provide the largest reduction in migraine frequency among analyzed nutritional supplements
Probiotics and Coenzyme Q10 Show Promise for Migraine Frequency
This network meta-analysis of 791 adult migraineurs evaluated vitamins, magnesium, coenzyme Q10, and probiotics. Probiotics showed the large…
New analysis shows that probiotics and coenzyme Q10 may reduce how often migraines occur, while magnesium specifically helps lower pain seve…
Sumatriptan/naproxen sodium and ibuprofen show significant pain freedom for pediatric migraine treatment
New analysis shows effective migraine treatments for children and adolescents
This network meta-analysis of 30 studies involving 8,914 participants evaluated acute migraine medications in children and adolescents. Suma…
A large review of 30 studies helps identify which medications provide the fastest relief from migraines in children and teenagers.
Propranolol shows potential for managing various neurological diseases including PTSD, migraine, and autism spectrum disorder
Propranolol Shows Promise for Brain Conditions
This systematic review synthesizes clinical and preclinical evidence regarding the effects of propranolol on several neurological conditions…
A new review suggests propranolol, a common blood pressure drug, may help with PTSD, autism, and more. Here's what it means.
Non-invasive vagus nerve stimulation reduces monthly headache days in migraine patients
Trial Shows Vagus Nerve Stimulation Reduces Migraine Frequency
This meta-analysis of 917 patients with migraine found that non-invasive vagus nerve stimulation (nVNS) significantly reduced monthly headac…
Non-invasive vagus nerve stimulation may reduce the number of monthly headache days and the need for acute medication for people living with…
Transcutaneous Vagus Nerve Stimulation utilizes distinct auricular and cervical pathways for non-invasive treatment applications
Two different ways to stimulate the vagus nerve for treatment
This narrative review examines the anatomical access points and methodologies for transcutaneous Vagus Nerve Stimulation (tVNS). It distingu…
New research highlights two distinct paths for non-invasive nerve stimulation to treat conditions like migraine and depression.
30% of pediatric patients with migraine report at least one adverse event during pharmacological prophylaxis
Trial Shows Specific Side Effects for Children with Migraine
This meta-analysis of 2742 patients evaluates the safety profile of various pharmacological migraine prophylaxis treatments in children and …
About 30% of children and adolescents taking migraine prevention medication report experiencing at least one side effect during treatment.
Migraine patients may have an increased risk of neovascular age-related macular degeneration
Migraine patients may face higher risk of certain eye conditions
This narrative review examines the association between migraine and various retinal conditions, including retinal migraine and AMD. The auth…
New research highlights a link between migraines and age-related macular degeneration, potentially impacting long-term vision for many suffe…
Endometriosis genetic risk score tied to pain, cardiometabolic conditions in both sexes
Genetic Risk for Endometriosis Linked to Chronic Pain Conditions
This meta-analysis links an endometriosis polygenic risk score (PRS) to 20 of 29 comorbidities in women and to pain and cardiometabolic cond…
A large genetic study reveals that the same genetic markers linked to endometriosis are also associated with fibromyalgia, migraine, and bac…
Questions about vestibular migraine
Can vestibular migraine be differentiated from other conditions using neurotological evaluation?
Neurotological evaluation can help distinguish vestibular migraine from other conditions, though it can be challenging because migraine can mimic certain acute vestibular disorders.
Full answer →Is the cerebellum a primary generator of vestibular migraine attacks?
The cerebellum is considered a modulatory component of migraine networks rather than a primary generator of vestibular migraine attacks.
Full answer →