Early prophylactic hydrocortisone does not reduce bronchopulmonary dysplasia or mortality in extremely preterm infants
Early Hydrocortisone Treatment Shows Risks for Preterm Infants
This meta-analysis of 3,416 infants born before 30 weeks' gestation found that early low-dose hydrocortisone did not significantly improve s…
Early use of low-dose hydrocortisone in very premature infants does not reduce lung disease but may increase the risk of late-onset sepsis.
Adrenalectomy for Cushing Syndrome May Resolve Levothyroxine-Dependent Hypothyroidism in Pregnancy
Pregnancy and Cushing syndrome may hide a thyroid issue
This case report describes a 29-year-old woman at 17 weeks of gestation with Cushing syndrome and hypothyroidism who underwent retroperitone…
A pregnant woman with Cushing syndrome was able to stop taking thyroid medication after surgery to treat her hormone levels.
Hydrocortisone Linked to Favorable Course in First Triple A Syndrome Case in French Guiana
Rare Triple A Syndrome Diagnosed in French Guiana Boy
This is a single case report of a 5-year-old boy in French Guiana with Triple A syndrome, confirmed by a homozygous pathogenic AAAS variant,…
A 5-year-old boy in French Guiana is the first confirmed case of Triple A syndrome there, with a favorable response to hydrocortisone.
Low-dose corticosteroids reduce 90-day mortality in adults with severe community-acquired pneumonia
Low dose steroids may lower death rates in severe lung infections
This meta-analysis of 4,622 patients found that low-dose corticosteroids (≤400 mg hydrocortisone-equivalent daily) significantly reduced sho…
A review of clinical trials suggests that low-dose corticosteroids can reduce 90-day mortality for adults with severe lung infections like p…
Vasopressin, steroids, and epinephrine triple therapy improves ROSC in in-hospital cardiac arrest
Triple Therapy Shows Promise in Improving Cardiac Arrest Outcomes
This meta-analysis of 3 randomized trials and a network meta-analysis of 21,768 patients evaluates vasopressin, steroids, and epinephrine (V…
A triple therapy of vasopressin, steroids, and epinephrine showed a link to better circulation after cardiac arrest.
Corticosteroids reduce short-term and long-term mortality in adult sepsis patients according to a systematic review
What Doctors Give Sepsis Patients Is Finally Getting Clearer
This systematic review and network meta-analysis evaluated corticosteroids, specifically hydrocortisone and hydrocortisone plus fludrocortis…
Corticosteroids cut short-term and long-term sepsis death risk for ICU adults in large review, though doctors still need clearer guidance on…
Hair cortisol concentration correlates with glucocorticoid adequacy and symptoms in adults with adrenal insufficiency
Your Hair Holds a Hidden Record of a Dangerous Hormone Imbalance
This cross-sectional study evaluated hair cortisol concentration (HCC) in 64 adults with hydrocortisone-treated adrenal insufficiency compar…
A strand of hair can reveal months of hormone history, helping fine-tune treatment for adrenal insufficiency to avoid dangerous over- or und…
Immune dysregulation score predicts mortality and identifies hydrocortisone responders in community-acquired pneumonia
Three Blood Markers May Pick Who Benefits From Sepsis Steroids
A multicohort analysis and reanalysis of an RCT developed and validated an immune dysregulation score using three plasma biomarkers in 398 d…
A simple three-blood-test model may finally pick which sepsis patients benefit most from steroid treatment, using biology instead of guesswo…
Phase 2 trial protocol tests oral hydrocortisone for PTSD prevention after trauma
Study tests single hydrocortisone pill after trauma to prevent PTSD symptoms
A phase 2 randomized controlled trial protocol describes a study of 201 trauma survivors in emergency departments.
A single hydrocortisone pill taken within six hours of trauma might help the brain process memories differently to prevent PTSD symptoms in …