Corticosteroids reduce short-term and long-term mortality in adult sepsis patients according to a systematic review.
What Doctors Give Sepsis Patients Is Finally Getting Clearer
This systematic review and network meta-analysis evaluated corticosteroids, specifically hydrocortisone and hydrocortisone plus fludrocortis…
Corticosteroids cut short-term and long-term sepsis death risk for ICU adults in large review, though doctors still need clearer guidance on…
Hair cortisol concentration correlates with glucocorticoid adequacy and symptoms in adults with adrenal insufficiency.
Your Hair Holds a Hidden Record of a Dangerous Hormone Imbalance
This cross-sectional study evaluated hair cortisol concentration (HCC) in 64 adults with hydrocortisone-treated adrenal insufficiency compar…
A strand of hair can reveal months of hormone history, helping fine-tune treatment for adrenal insufficiency to avoid dangerous over- or und…
Immune dysregulation score predicts mortality and identifies hydrocortisone responders in community-acquired pneumonia
Three Blood Markers May Pick Who Benefits From Sepsis Steroids
A multicohort analysis and reanalysis of an RCT developed and validated an immune dysregulation score using three plasma biomarkers in 398 d…
A simple three-blood-test model may finally pick which sepsis patients benefit most from steroid treatment, using biology instead of guesswo…
Phase 2 trial protocol tests oral hydrocortisone for PTSD prevention after trauma
Study tests single hydrocortisone pill after trauma to prevent PTSD symptoms
A phase 2 randomized controlled trial protocol describes a study of 201 trauma survivors in emergency departments. Participants receive a si…
A single hydrocortisone pill taken within six hours of trauma might help the brain process memories differently to prevent PTSD symptoms in …