Clinical Trial Search

Primary: Knowledge of Memory Aging Questionnaire-Revised — 19.8; 19.5 units on a scale

Primary: Changes in the Breakfast Game Performance: Number of Tables Set Score — 1.61; 1.43 score on a scale (change)

Primary: Percentage of Trials Correct On Working Memory Test — 87.69; 91.57; 88.01; 91.68 percentage of correct trials — p=>0.05

Primary: Change in Hippocampal-dependent Learning — -.00369; .00404 learning rate (proportion correct/trial) — p=<.05

Primary: Magnetic Resonance Spectroscopy (MRS) Will Measure a Change in Cerebral Energy Function in Brain Tissue — .011; .007; .009; .006 Difference in metabolite amplitude

Primary: Blood Oxygen Level-dependent (BOLD) Response to High-calorie Foods Cues Minus Neutral Objects in Left Anterior Cingulate Cortex — -0.05; -0.16 percent BOLD signal change

Primary: Simple Reaction Time (Attention) — 287.7 ms

Primary: Change in Mean Global Composite Cognition Score From Baseline — 0.2; 0.2 Z-score — p=0.259

Primary: Working Memory — 0.86; 0.04 digits recalled

Primary: Leisure Activities Questionnaire Activities Sum — 1.45; 4.45; 11.25 score on a scale — p=<0.05

Primary: Cognitive and Memory Function — 56.5; 49.8 score on a scale

Primary: Estimated Weekly Change on World Health Organization-5 (WHO-5) — 0.78; 0.76; 0.41; 0.33 estimated weekly change in scale score — p=.820

Primary: Verbal Memory Score Change — -0.08; -0.08; 0.18; -0.47 score on a scale

Primary: Agreement Analysis (Agreement to Reference Standard) - Test Group — 76; 18; 2; 8 Participants

Primary: Task Completion Rate — 66; 57 Percentage of eligible participants

Primary: Change in NIH Toolbox Fluid Cognition Composite Score — 4.7; 6.1 units on a scale

Primary: Total Number of Goals Improved to Criterion on the Canadian Occupational Performance Measure (COPM) — 50; 19.6; 50; 32.6 percentage of untrained goals improved — p=0.03

Primary: Geriatric Depression Scale Change Score — .89; 0.50 score on a scale

Primary: Change in Cognitive Function — 0.28; .65; 1.84; -.73 T score

Primary: Executive Cognitive Function Composite Score — 0.211; 0.100; 0.142; 0.196 units on a scale

Primary: Delay Eyeblink Conditioning — 52.32; 56.88 percentage of conditioned responses

Primary: Creyos Cognitive Composite - 3 Month — 0.27; 0.13 Change on z-score — p=0.346

Primary: Mean Change in ADL Score From Baseline to Week 10 — 0.00; -0.29 score on a scale

Primary: Change From Baseline in California Verbal Learning Task Score — 3.04; 5.17; 4.22; 7.04 score on a scale

Primary: Differences in Error Rates on the NBack Task Between Real and Sham Stimulation Trials — -0.79; -0.1 incorrect responses

Primary: Change in East Boston Memory Test Scores From Baseline to 24 Weeks, 48 Weeks, and 72 Weeks — 0.03; -0.02; 0.01; 0.05 score on a scale — p=.409

Primary: Change From Baseline on a Composite Measure (Z-score) of Attention, Working Memory, and Executive Functions — 0.26; .01 Change to Z (composite) score

Primary: Object Location Touchscreen Task (Version C) Free Recall Total Error — 121.498; 99.77 centimeters — p=.300

Primary: N-Back Working Memory — .2030; .0731 percent change

Primary: Change of Cognitive Function Measured by a Mini Mental State Examination Scores on a Scale According to Study Group — 23.3; 23.8; 23.1; 23.7 units on a scale