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Psychiatry
Cohort
MDD polygenic scores show adolescence-specific effects on child depressive symptoms in Norwegian cohort
Teen Depression Linked to Genes That "Switch On" at Puberty
This cohort study of children from the Norwegian Mother, Father and Child Cohort assessed depressive symptoms at ages 8 and 14. Children's o…
Your teen's depression risk may be written in their genes, but only becomes visible during puberty's hormonal storm.
medRxiv
Apr 26, 2026
Psychiatry
Cohort
Polygenic risk scores show stronger associations with comorbid anxiety and depression cases in cohort studies
Do anxiety and depression share the same genetic roots when they appear together?
This observational cohort study in UK Biobank and MoBa participants found polygenic risk scores for anxiety and depression were more strongl…
When anxiety and depression occur together, their shared genetic risk is much stronger than when each disorder appears alone.
medRxiv
Apr 19, 2026
Psychiatry
Cohort
Plasma NfL levels elevated in bipolar and depressive disorders in UK Biobank cohort
Brain Scans Show Hidden Signals in Mental Health
A cohort study of 47,495 UK Biobank participants found plasma neurofilament light chain (NfL) levels were higher in bipolar disorder (d=0.20…
Blood tests now reveal hidden brain signals that distinguish depression from anxiety, offering clearer paths to the right treatment for mill…
medRxiv
Apr 14, 2026
Psychiatry
Cohort
MPNFS-based psychological intervention linked to reduced anxiety in adolescents with anxiety disorders
Psychological intervention shows promise for reducing anxiety in adolescents
A retrospective cohort study of 196 adolescents with anxiety disorders found that a 6-week MPNFS-based integrative psychological interventio…
Teenagers with anxiety disorders showed significantly greater improvement after a six-week psychological intervention compared to standard c…
Frontiers
Apr 7, 2026
Psychiatry
Movement patterns during threat task associated with symptom profiles in young children
How do anxious children move differently when they feel threatened?
An observational laboratory study of 91 children aged 4-8 years found that internalizing symptoms were associated with smaller turning angle…
Wearable sensors show anxious children turn less when threatened, but those with both anxiety and aggression turn more, signaling different …
medRxiv
Apr 4, 2026
Psychiatry
Group Metacognitive Therapy Shows Large Symptom Reductions in Students with Anxiety
Group therapy for student anxiety shows promising results in small, early study
An uncontrolled pre-post study of students with anxiety disorders or elevated symptoms found group Metacognitive Therapy (gMCT) delivered in…
Group therapy for student anxiety showed large symptom reductions and lasting benefits in an early study at a university clinic in Oslo.
Frontiers
Apr 1, 2026