Research across Stroke
Related studies from across the Stroke family.
Intracranial hemorrhage rates were higher in tenecteplase than standard care at 14.4% versus 9.2% in minor ischemic stroke
Even small bleeds after minor stroke raise death risk in this trial analysis
This secondary analysis of a multicenter randomized controlled trial evaluated 865 patients with minor ischemic stroke within 12 hours of sy…
A look at trial data shows that small bleeds after minor stroke are linked to higher death rates, even if they do not worsen long-term funct…
Atractylenolide III shows neuroprotective effects in preclinical CNS disorder models
Atractylenolide III shows promise for brain and nerve injuries in lab models
This narrative review summarizes preclinical evidence that Atractylenolide III exerts neuroprotective effects in models of cognitive impairm…
Atractylenolide III looks like a helpful option for brain and nerve damage in early lab tests, though human trials are needed.
Case report details treatment of ANCA-associated vasculitis with Evans syndrome and cerebral infarction in a 72-year-old woman
Treatment stabilized some symptoms but not others in a single patient case
This case report describes a 72-year-old female with ANCA-associated vasculitis, Evans syndrome, and cerebral infarction treated with cortic…
A 72-year-old woman with complex blood vessel disease saw some health markers improve while others remained poor after specific treatments.
Review synthesizes neuroprotective potential of TCM metabolites using zebrafish models for neurological conditions
Traditional Chinese medicine metabolites protect brain cells from damage
This review examines the utility of Traditional Chinese medicine (TCM) metabolites for neurological conditions including Alzheimer's disease…
A review shows Traditional Chinese medicine metabolites protect brain cells through anti-inflammatory and anti-oxidative stress actions, off…
Evidence summary on glycemic variability management in ICU patients with cerebral infarction
ICU Guidelines Suggest Managing Blood Sugar Swings During Feeding
This evidence summary synthesizes 18 documents on glycemic variability management during enteral nutrition for adult ICU patients with cereb…
Guidelines advise managing blood sugar swings in ICU patients receiving tube feeding, noting that individual adjustments depend on local res…
Stroke scale expansions improve posterior circulation deficit detection
New tools help doctors spot brain issues in the back part of the head better than old methods
Expanded NIHSS and posterior-specific tools enhance sensitivity for posterior stroke deficits, aiding bedside assessment and prognostic stra…
Doctors are using new scales to find strokes in the back of the brain. These tools work better than the standard ones used today.
Systematic review and meta-analysis on EVT for anterior circulation LVO with low ASPECTS
Stroke patients regain independence years after clot removal procedure
This systematic review and meta-analysis synthesized evidence on endovascular thrombectomy for patients with anterior circulation large vess…
A clot-removal procedure that already helps severe stroke patients at 90 days now shows those benefits hold strong for a full year or more.
Meta-analysis of preclinical studies suggests ligustrazine improves outcomes in cerebral ischemia-reperfusion injury
New data shows Ligustrazine helps brain recovery after stroke-like events in animals
This meta-analysis of preclinical animal studies evaluated ligustrazine for cerebral ischemia-reperfusion injury. Pooled results from 381 an…
New research suggests a specific plant compound could help the brain recover after blood flow is restored following a blockage
Review of SPMs for stroke notes promising neuroprotective effects with delivery limitations
Your Brain's Natural Healing Helpers Could Change Stroke Recovery
This review examines the role of exogenous administration of SPMs or their stable analogs in cerebral ischemia-reperfusion and stroke. The a…
After stroke, the brain's own healing chemicals might prevent lasting damage, but human trials haven't started yet.
Sex differences in outcomes after stroke in NVAF with ASCVD: a post hoc analysis
Women and Men With AFib and Clogged Arteries Share Same Stroke Risk
This post hoc analysis of an RCT included 222 patients with recent ischemic stroke or TIA, NVAF, and ASCVD. No significant sex differences w…
Women and men with AFib and clogged arteries face similar risks for stroke, heart attack, and bleeding over two years.
Meta-analysis finds no benefit of IV thrombolysis for minor ischemic stroke
Clot-busting drugs did not improve function but raised bleeding risk for minor strokes
This systematic review and meta-analysis of RCTs involving 4,361 patients with minor ischemic stroke (NIHSS ≤5) found no significant differe…
A large review found clot-busting drugs offered no benefit for minor strokes but significantly increased the risk of dangerous brain bleedin…
Non-immersive virtual reality for upper limb motor function after chronic stroke
New Virtual Reality Training Helps Stroke Patients Regain Arm Movement
This randomized controlled trial in 26 patients with chronic middle cerebral artery stroke compared non-immersive virtual reality to convent…
A new virtual reality tool helps stroke patients regain arm movement skills in a way that standard therapy alone cannot match.