Research across Stroke
Related studies from across the Stroke family.
Neuroecosystem Collapse Framework Links Ferroptosis, Neuroinflammation, and Gut-Brain Axis to Post-Stroke Cognitive Impairment
New Framework Explains How Stroke Impacts Brain Function
This systematic review proposes a neuroecosystem framework for post-stroke cognitive impairment, reinterpreting ferroptosis, neuroinflammati…
A new framework identifies how the interaction between blood vessels, immune cells, and brain cells may drive cognitive issues after a strok…
Clopidogrel plus aspirin for 21 days provides favorable net clinical benefit in minor ischemic stroke
Dual antiplatelet therapy shows mixed results for stroke prevention
This Bayesian network meta-analysis of 8 trials involving 50,349 adults with minor ischemic stroke or high-risk TIA found that clopidogrel p…
New data compares different blood thinner combinations to find the best way to prevent a second stroke after a minor medical emergency.
Traditional Chinese medicine may activate Wnt/beta-catenin signaling pathways in cerebral ischemia and reperfusion injury
Traditional Chinese Medicine Shows Potential for Ischemic Stroke Recovery
This systematic review examines the mechanisms of traditional Chinese medicine (TCM) in treating ischemic stroke and cerebral ischemia/reper…
New research explores how traditional Chinese medicine components may protect brain cells and support recovery after an ischemic stroke.
Ligustilide shows neuroprotective effects across multiple CNS disorders in preclinical models
Ligustilide Shows Potential for Treating Various Brain Disorders
This systematic review of 55 original studies evaluates the neuroprotective potential of ligustilide (LIG) in various neurological condition…
Early research on the compound ligustilide shows potential to protect brain cells from damage caused by stroke, dementia, and other neurolog…
Intracranial hemorrhage rates were higher in tenecteplase than standard care at 14.4% versus 9.2% in minor ischemic stroke
Even small bleeds after minor stroke raise death risk in this trial analysis
This secondary analysis of a multicenter randomized controlled trial evaluated 865 patients with minor ischemic stroke within 12 hours of sy…
A look at trial data shows that small bleeds after minor stroke are linked to higher death rates, even if they do not worsen long-term funct…
Atractylenolide III shows neuroprotective effects in preclinical CNS disorder models
Atractylenolide III shows promise for brain and nerve injuries in lab models
This narrative review summarizes preclinical evidence that Atractylenolide III exerts neuroprotective effects in models of cognitive impairm…
Atractylenolide III looks like a helpful option for brain and nerve damage in early lab tests, though human trials are needed.
Case report details treatment of ANCA-associated vasculitis with Evans syndrome and cerebral infarction in a 72-year-old woman
Treatment stabilized some symptoms but not others in a single patient case
This case report describes a 72-year-old female with ANCA-associated vasculitis, Evans syndrome, and cerebral infarction treated with cortic…
A 72-year-old woman with complex blood vessel disease saw some health markers improve while others remained poor after specific treatments.
Review synthesizes neuroprotective potential of TCM metabolites using zebrafish models for neurological conditions
Traditional Chinese medicine metabolites protect brain cells from damage
This review examines the utility of Traditional Chinese medicine (TCM) metabolites for neurological conditions including Alzheimer's disease…
A review shows Traditional Chinese medicine metabolites protect brain cells through anti-inflammatory and anti-oxidative stress actions, off…
Evidence summary on glycemic variability management in ICU patients with cerebral infarction
ICU Guidelines Suggest Managing Blood Sugar Swings During Feeding
This evidence summary synthesizes 18 documents on glycemic variability management during enteral nutrition for adult ICU patients with cereb…
Guidelines advise managing blood sugar swings in ICU patients receiving tube feeding, noting that individual adjustments depend on local res…
Stroke scale expansions improve posterior circulation deficit detection
New tools help doctors spot brain issues in the back part of the head better than old methods
Expanded NIHSS and posterior-specific tools enhance sensitivity for posterior stroke deficits, aiding bedside assessment and prognostic stra…
Doctors are using new scales to find strokes in the back of the brain. These tools work better than the standard ones used today.
Systematic review and meta-analysis on EVT for anterior circulation LVO with low ASPECTS
Stroke patients regain independence years after clot removal procedure
This systematic review and meta-analysis synthesized evidence on endovascular thrombectomy for patients with anterior circulation large vess…
A clot-removal procedure that already helps severe stroke patients at 90 days now shows those benefits hold strong for a full year or more.
Meta-analysis of preclinical studies suggests ligustrazine improves outcomes in cerebral ischemia-reperfusion injury
New data shows Ligustrazine helps brain recovery after stroke-like events in animals
This meta-analysis of preclinical animal studies evaluated ligustrazine for cerebral ischemia-reperfusion injury. Pooled results from 381 an…
New research suggests a specific plant compound could help the brain recover after blood flow is restored following a blockage