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Infectious Disease
Sys. Review
Narrative synthesis reviews U.S. HPV vaccination policy impacts on initiation and completion rates.
One Simple Change Could Save Thousands From Cervical Cancer
This narrative synthesis reviews HPV vaccination policies across U.S. states, focusing on Medicaid expansion, pharmacist authority, and scho…
State laws, not just doctor advice, drive HPV vaccine success and help protect families from cervical cancer.
Frontiers
Apr 21, 2026
Oncology
Cohort
CLEC14A methylation marker detects HSIL and cervical cancer with 100% sensitivity and 95.3% specificity in a cohort of 431 participants.
Can a simple blood test spot dangerous cervical cell changes before they become cancer?
This cohort study of 431 participants evaluated the CLEC14A cg05057720 methylation marker for detecting high-grade squamous intraepithelial …
A new blood test marker detects every case of dangerous cervical cell changes while correctly identifying normal tissue in over 95% of cases…
Frontiers
Apr 16, 2026
Infectious Disease
Sys. Review
Systematic review examines innate immune recognition and PRR activation in HPV infection and cervical cancer progression.
How HPV Outsmarts Your Body's First Line of Defense
This mini-review synthesizes evidence regarding innate immune recognition, pattern recognition receptor activation, and HPV evasion strategi…
HPV evades the immune system by silencing its alarms, fueling cervical cancer and pointing to new ways to prevent it.
Frontiers
Apr 15, 2026
Primary Care & Family Medicine
Guideline
Survey finds accuracy most important attribute for HPV self-sampling acceptance in under-screened women
What Women Really Want From an At-Home Cervical Cancer Test
A cross-sectional survey of 200 women from under-screened populations assessed preferences for HPV self-sampling attributes. Accuracy had th…
To get women to use at-home cervical cancer tests, accuracy is four times more important than comfort or ease of use.
Frontiers
Apr 13, 2026
Infectious Disease
Meta-analysis
Meta-analysis of NHPI populations shows low pooled Pap testing and HPV vaccine initiation rates with high treatment disparities.
Imagine a cancer we know how to prevent. A simple test can catch it early. A vaccine can stop it before it starts.
This systematic review and meta-analysis evaluated cervical cancer prevention metrics and treatment disparities in Native Hawaiian and Pacif…
This research uncovers a severe and life-threatening inequity in cancer care for a community often overlooked in health data.
Apr 10, 2026
Oncology
Meta-analysis
Tumor budding associates with adverse clinicopathological features and reduced overall survival in cervical and endometrial cancer.
Tumor Budding Linked to Worse Outcomes in Cervical and Endometrial Cancer
This Bayesian meta-analysis of 18 observational cohort studies involving 3320 patients with cervical or endometrial cancer evaluated the pro…
Small clusters of cells breaking away from cervical and endometrial tumors signal more aggressive disease and worse survival outcomes.
Apr 9, 2026
Oncology
Sys. Review
Precision oncology enables targeted therapies for gynecologic cancers, though acquired resistance remains a barrier.
Precision oncology advances gynecologic cancer care but resistance remains a major barrier
This systematic review examined the current landscape of precision oncology for patients with endometrial, ovarian, and cervical carcinomas.…
Molecular reclassification lets doctors use targeted drugs effectively for gynecologic cancers, but tumor evolution creates a major barrier …
Frontiers
Apr 9, 2026
Oncology
Meta-analysis
Meta-analysis finds [68Ga]Ga-FAPI PET shows high diagnostic accuracy for gynecologic cancers
Could a new scan spot breast and ovarian cancer tumors better than the standard test?
A meta-analysis of 253 females with breast, ovarian, and cervical cancers compared [68Ga]Ga-FAPI PET to [18F]F-FDG PET imaging. [68Ga]Ga-FAP…
A new scan using a different tracer finds breast, ovarian, and cervical cancer tumors and spread much better than the standard test doctors …
Apr 9, 2026
Oncology
Cohort
Radiomics and AI show promise for cervical cancer radiotherapy but face validation and standardization challenges.
AI tools show promise for cervical cancer radiotherapy but need more testing
This narrative review examines the application of radiomics and artificial intelligence (AI) in precision radiotherapy for women with cervic…
AI tools show promise for cervical cancer radiotherapy but need more testing before becoming standard care for patients.
Frontiers
Apr 9, 2026
OB/GYN & Women's Health
Meta-analysis
HPV cfDNA testing shows high specificity but moderate sensitivity for cervical cancer detection
Blood test for HPV DNA shows promise for monitoring cervical cancer after treatment
A meta-analysis of 20 studies in HPV-positive cervical cancer patients found HPV cfDNA testing had pooled sensitivity of 0.47 and specificit…
A review of 20 studies found that a blood test looking for HPV DNA was very specific for detecting cervical cancer, but it missed about half…
Apr 8, 2026
OB/GYN & Women's Health
RCT
Low-intensity cervical screening shows similar CIN2+ risk to high-intensity screening in HPV-vaccinated women
Study finds similar cervical cancer risk with less frequent screening for HPV-vaccinated women
An RCT in Finland followed 5626 women vaccinated against HPV16/18 as adolescents, comparing low-intensity to high-intensity cytology-based s…
HPV-vaccinated women aged 12 to 15 face the same cervical cancer risk whether screened every three years or every five years, according to n…
Apr 3, 2026
OB/GYN & Women's Health
RCT
ED-based cervical cancer screening finds elevated abnormal Pap rates and high-risk HPV in trial participants
ED cervical cancer screening finds higher abnormal Pap rates than national average
An RCT of 181 women ages 21-65 who received ED-based cervical cancer screening found 12% had abnormal Pap tests (significantly elevated vs. …
Emergency department cervical cancer screening found 12% abnormal Pap results, far higher than the national average of 3.8%.
Apr 3, 2026