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Home › Conditions › Cervical Intraepithelial Neoplasia

Cervical Intraepithelial Neoplasia

Part of Uterine Cervical Diseases

3 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Cervical Intraepithelial Neoplasia

20 trials tracked for Cervical Intraepithelial Neoplasia: 8 in phase 3 or 4 and 1 with published results. The most-cited published study has 7 citations.

20Trials tracked
8Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 4 2 Phase 3 6 Phase 2 7 Other / NA 5
  1. Phase 4 V501 Safety and Efficacy Study in Japanese Women Aged 16 to 26 Years (V501-110) Completed · 7 cited
  2. Phase 4 Safety and Protective Effect Study of GSK Biologicals' Human Papillomavirus (Types 16, 18) Vaccine, Adsorbed (GSK580299) in Healthy Female Subjects From the HPV-039 Study Completed
  3. Phase 3 Randomized Clinical Trial on Clinical Management of ASCUS and LSIL (ALTS) Completed
  4. Phase 3 A Follow-up Extension Study to Evaluate the Persistence of Immune Response to GSK Biologicals' HPV Vaccine in Healthy Chinese Female Subjects Who Received Three Doses of the Vaccine in the HPV-058 Study Completed
  5. Phase 3 Human Papilloma Virus (HPV) Vaccine Trial in Young Adolescent Women With GlaxoSmithKline Biologicals' (GSK Bio) HPV-16/18 Vaccine Completed
  6. Phase 3 Efficacy Study of Diathermy Cone Biopsy for the Treatment of Cervical Intraepithelial Lesion Completed
Show 14 more trials
  1. Phase 3 Human Papillomavirus (HPV) Vaccine Consistency and Non-inferiority Trial in Young Adult Women Completed
  2. Phase 3 A Trial of Two Electrosurgical Conizations: Histopathological Analysis of Excision Margins Completed
  3. Phase 2 A Trial for Patients With Advanced/Recurrent Cervical Cancer Completed
  4. Phase 2 A Study on the Immune Response and Safety of an Adjuvanted Human Papillomavirus Vaccine When Given to Healthy Women 16 to 26 Years of Age Completed
  5. Phase 2 Treatment of High-Grade Pre-Neoplastic Cervical Lesions (CIN 2/3) Completed
  6. Phase 2 A Clinical Trial of PepCan to Two Therapy Arms for Treating Cervical High-Grade Squamous Intraepithelial Lesions Completed
  7. Phase 2 Dose-finding Study of Hexaminolevulinate (HAL) Photodynamic Therapy (PDT) to Treat Cervical Neoplasia Completed
  8. Phase 2 E7 TCR T Cells for Human Papillomavirus-Associated Cancers Completed
  9. Phase 2 Safety and Efficacy of A-007 Topical Gel in the Treatment of High-Grade Squamous Intraepithelial Lesions (HSIL) of the Cervix Completed
  10. N/A An Innovative Treatment for Cervical Precancer (UH3) Completed
  11. N/A Evaluation of Human Papilloma Virus (HPV) Self-testing to Increase Screening Uptake Completed
  12. N/A Cryotherapy vs. LEEP to Treat Cervical Intraepithelial Neoplasia (CIN) 2/3 Among HIV-positive Women Completed
  13. N/A An Innovative Treatment for Cervical Pre Cancer Completed
  14. N/A A Post Marketing Surveillance (PMS) Study to Monitor the Safety of GlaxoSmithKline (GSK) Biologicals' Human Papillomavirus (HPV) Vaccine in Female Chinese Subjects Completed

Showing the 20 most-cited and recently-updated of 20 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Low-intensity cervical screening shows similar CIN2+ risk to high-intensity screening in HPV-vaccinated women
OB/GYN & Women's Health RCT
Low-intensity cervical screening shows similar CIN2+ risk to high-intensity screening in HPV-vaccinated women Study finds similar cervical cancer risk with less frequent screening for HPV-vaccinated women
An RCT in Finland followed 5626 women vaccinated against HPV16/18 as adolescents, comparing low-intensity to high-intensity cytology-based s…
HPV-vaccinated women aged 12 to 15 face the same cervical cancer risk whether screened every three years or every five years, according to n…
Jun 4, 2026
Cervical blockade reduces pain and bleeding during LEEP for HSIL in small RCT
OB/GYN & Women's Health RCT
Cervical blockade reduces pain and bleeding during LEEP for HSIL in small RCT Local cervical anesthesia reduces pain and bleeding during cervical surgery
A small, open-label RCT of 40 patients with HSIL undergoing LEEP found that adding cervical blockade to general anesthesia significantly red…
Adding local anesthesia to cervical surgery reduced pain and bleeding during the procedure for patients having LEEP to remove abnormal cells…
Apr 8, 2026
Focused ultrasound shows HPV clearance, LSIL resolution in meta-analysis of observational studies
Oncology Meta-analysis
Focused ultrasound shows HPV clearance, LSIL resolution in meta-analysis of observational studies Focused ultrasound shows promise for treating cervical cell changes and HPV
A meta-analysis of observational studies in women with cervical LSIL and concurrent hrHPV infection found focused ultrasound treatment was a…
Focused ultrasound cleared HPV in 74% of women and returned cervical cell changes to normal in 94%, outperforming observation and interferon…
Apr 4, 2026

Research across Uterine Cervical Diseases

Related studies from across the Uterine Cervical Diseases family.

Prospective study links L. iners dominance and bacterial diversity to cervical lesion severity in dysplasia patients
OB/GYN & Women's Health Cohort
Prospective study links L. iners dominance and bacterial diversity to cervical lesion severity in dysplasia patients Does the bacteria in your vagina signal worsening cervical cell changes?
This prospective study analyzed vaginal microbiota in 91 patients with cervical dysplasia.
Women with worsening cervical cell changes showed higher levels of L. iners bacteria and increased bacterial diversity in their vaginal samp…
Frontiers Apr 6, 2026