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Cognitive impairment associated with schizophrenia

Part of Schizophrenia

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for Cognitive impairment associated with schizophrenia

2 trials tracked for Cognitive impairment associated with schizophrenia.

2Trials tracked
0Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 2 1 Phase 1 1
  1. Phase 2 A Study to Evaluate the Safety and Efficacy of BIIB104 in Participants With Cognitive Impairment Associated With Schizophrenia (CIAS) Completed
  2. Phase 1 Evoked Responses as Pharmacodynamic Biomarkers in Healthy and Schizophrenic Participants (MK-4334-007) Completed

Showing the 2 most-cited and recently-updated of 2 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Schizophrenia

Related studies from across the Schizophrenia family.

Prenatal exposure to certain psychotropic medications is associated with increased risk of gestational diabetes
Diabetes & Endocrinology Meta-analysis
Prenatal exposure to certain psychotropic medications is associated with increased risk of gestational diabetes Prenatal exposure to certain psychiatric drugs linked to gestational diabetes
This meta-analysis examined the relationship between prenatal exposure to antipsychotics and antidepressants and the risk of gestational dia…
New data shows that some medications used for mental health during pregnancy may increase the risk of gestational diabetes.
Shared gray matter volume reductions in ventromedial prefrontal cortex and insula across schizophrenia, MDD, and AUD
Psychiatry Meta-analysis
Shared gray matter volume reductions in ventromedial prefrontal cortex and insula across schizophrenia, MDD, and AUD Shared Brain Structure Changes Link Schizophrenia, Depression, and Alcohol Use
This meta-analysis of imaging data identifies shared gray matter volume deficits in the ventromedial prefrontal cortex, ventral anterior cin…
New research identifies shared gray matter reductions in the brain for people with schizophrenia, depression, and alcohol use disorders.
Vitamin C supplementation may reduce psychotic symptoms in patients with schizophrenia
Nutrition & Obesity Medicine Meta-analysis
Vitamin C supplementation may reduce psychotic symptoms in patients with schizophrenia Vitamin C Supplementation May Reduce Symptoms in Schizophrenia Patients
The meta-analysis examined circulating vitamin C levels and the effects of supplementation on psychotic symptoms in patients with schizophre…
Lower vitamin C levels are linked to schizophrenia, and supplementation may help reduce psychotic symptoms in patients.
Higher baseline PANSS Negative scores predict 21% lower relapse risk in schizophrenia
Psychiatry RCT
Higher baseline PANSS Negative scores predict 21% lower relapse risk in schizophrenia Higher Negative Symptoms Linked to Lower Schizophrenia Relapse Risk
This pooled analysis of five randomized trials involving 557 patients with schizophrenia found that higher baseline PANSS Negative scores pr…
New data suggests that the severity of negative symptoms in schizophrenia may help predict the risk of a relapse after stopping medication.
Resting-state functional MRI reveals distinct regional homogeneity patterns in MDD, BD, and Schizophrenia
Psychiatry Meta-analysis
Resting-state functional MRI reveals distinct regional homogeneity patterns in MDD, BD, and Schizophrenia Brain Imaging Reveals Shared Patterns in Depression and Schizophrenia
This meta-analysis of resting-state functional MRI studies identifies specific regional homogeneity (ReHo) abnormalities in patients with MD…
New research identifies specific brain activity patterns that overlap and differ between depression, bipolar disorder, and schizophrenia.
Depression and Schizophrenia Stereotypes Differ in Warmth but Not Competence
Psychiatry Meta-analysis
Depression and Schizophrenia Stereotypes Differ in Warmth but Not Competence People view schizophrenia as less warm than depression
This meta-analysis of 17 studies used the stereotype content model to compare warmth and competence ratings for depression versus schizophre…
New data shows that while people view both conditions as equally capable, they view those with schizophrenia as less warm.
Metacognitive training improves clinical insight in schizophrenia compared to non-metacognitive targeted approaches
Psychiatry Sys. Review
Metacognitive training improves clinical insight in schizophrenia compared to non-metacognitive targeted approaches Metacognitive training helps people with schizophrenia gain insight into illness
This narrative review explores the role of metacognitive processes in schizophrenia and the efficacy of specific interventions. The authors …
New research shows that targeting specific thinking processes can help people with schizophrenia better understand their own condition.
Higher baseline PANSS negative symptom severity associated with lower risk of symptom exacerbation
Psychiatry RCT
Higher baseline PANSS negative symptom severity associated with lower risk of symptom exacerbation Higher Baseline Negative Symptoms Linked to More Stable Schizophrenia Course
This RCT of 1139 adults with schizophrenia found that patients in the medium and high baseline PANSS negative symptom tertiles had a lower r…
People with schizophrenia who have more severe negative symptoms at the start of treatment may experience fewer sudden flare-ups over 18 mon…
Meta-analysis finds no atypical reliance on priors in schizophrenia-spectrum psychosis
Psychiatry Meta-analysis
Meta-analysis finds no atypical reliance on priors in schizophrenia-spectrum psychosis New findings clarify how the brain processes information in people with schizophrenia
This meta-analysis of behavioral measures found no evidence for atypical reliance on priors in adults with schizophrenia-spectrum psychosis …
Researchers looked at how people with schizophrenia process information. They found no evidence for a general flaw in how the brain predicts…
Barriers to mental health care for Black populations include racism, stigma, and socioeconomic determinants
Psychiatry Sys. Review
Barriers to mental health care for Black populations include racism, stigma, and socioeconomic determinants Barriers to mental health care for Black patients identified
This scoping review of 254 sources identifies prevalent mental health disorders and systemic barriers affecting the Black population. Key fi…
New research highlights how racism, stigma, and lack of access create significant hurdles for Black people seeking mental health care.
Semaglutide and liraglutide are associated with the greatest weight reductions in patients with schizophrenia
Psychiatry Sys. Review
Semaglutide and liraglutide are associated with the greatest weight reductions in patients with schizophrenia New data shows weight loss options for people with schizophrenia
This network meta-analysis of 5898 patients with schizophrenia spectrum disorders evaluated pharmacological interventions for weight reducti…
New data identifies specific medications that help people with schizophrenia manage weight gain while staying on their standard antipsychoti…
Aerobic exercise combined with tai chi may reduce Positive and Negative Syndrome Scale scores
Psychiatry Sys. Review
Aerobic exercise combined with tai chi may reduce Positive and Negative Syndrome Scale scores Exercise and yoga may help manage symptoms of schizophrenia
This network meta-analysis of 2628 individuals with schizophrenia evaluated the efficacy of aerobic exercise, yoga, and tai chi. The analysi…
New research suggests that aerobic exercise, yoga, and tai chi could help reduce both positive and negative symptoms in people with schizoph…