Research across Schizophrenia
Related studies from across the Schizophrenia family.
GLP-1R exposure shows no causal link to most mental disorders except eating disorders
GLP-1 Receptor Agonists Show Mixed Links to Mental Health
This meta-analysis investigated the causal associations between GLP-1 receptor agonists and various mental health outcomes including anxiety…
New research explores how GLP-1 receptor agonists relate to conditions like anxiety and depression, finding no clear genetic link to most di…
Resting-state qEEG identifies distinct neurophysiological signatures in chronic schizophrenia compared to first-episode psychosis
Brain wave patterns help distinguish schizophrenia from early psychosis
This systematic review of 19 studies evaluates resting-state quantitative electroencephalography (qEEG) as a biomarker for schizophrenia and…
New research shows that specific brain wave changes can tell the difference between chronic schizophrenia and first-episode psychosis.
Virtual reality interventions significantly improve core symptoms and cognitive function in patients with schizophrenia
Virtual reality helps manage core symptoms of schizophrenia
This meta-analysis of 678 individuals with schizophrenia found that virtual reality (VR) interventions significantly improved overall psychi…
New data shows virtual reality can improve cognitive function and reduce key symptoms for people living with schizophrenia.
Public health interventions improve mental health in young people in LMICs: systematic review
Public health interventions improve mental health in young people in LMICs
A systematic review of 30 studies found that public health interventions, including digital health, improved mental health outcomes in young…
A review of 30 studies finds that public health interventions, including digital tools, can improve mental health in young people in low-inc…
Semaglutide Improves Metabolic Health in Schizophrenia Patients on Antipsychotics
Semaglutide improves blood sugar and weight in people with schizophrenia and prediabetes
A randomized, placebo-controlled trial in 154 overweight or obese individuals with schizophrenia and prediabetes receiving second-generation…
A new trial shows semaglutide helps lower blood sugar and reduce weight in people with schizophrenia who also have prediabetes or obesity.
Expressive writing plus digital cognitive therapy may aid schizophrenia recovery
Expressive writing and digital therapy may help schizophrenia recovery
This narrative review proposes integrating expressive writing with digital cognitive therapy for schizophrenia. The authors argue this combi…
A narrative review suggests combining expressive writing with digital cognitive therapy could improve functional outcomes for people with sc…
Brexpiprazole improves PANSS scores by 0.19 Cohen's d in early-episode schizophrenia versus placebo
Brexpiprazole helps early schizophrenia symptoms more than placebo in adults and teens
This post hoc analysis of Phase 3 trials evaluated brexpiprazole versus placebo in 476 adults and adolescents aged 13-35 years with early-ep…
A look at trial data shows brexpiprazole improved symptoms and daily functioning better than placebo for people with early schizophrenia.
Short allele of 5-HTTLPR linked to increased schizophrenia risk in Japanese cohort and meta-analysis
Short gene variant linked to schizophrenia risk in Japanese ancestry patients
This cohort study and meta-analysis in Japanese patients found a significant association between the 5-HTTLPR short allele and schizophrenia…
A specific gene variant appears more common in people with schizophrenia than in controls, suggesting a possible link to disease risk.
Pimavanserin adjunctive therapy shows small statistically significant reductions in PANSS scores below clinically meaningful thresholds for schizophrenia
Review finds pimavanserin offers little for schizophrenia negative symptoms
This systematic review and meta-analysis evaluated adjunctive pimavanserin in 1676 randomized participants with schizophrenia. The analysis …
A major review of 1,676 adults with schizophrenia found adding pimavanserin did not meaningfully improve negative symptoms, despite small st…
Systematic review and meta-analysis of gut microbiota in schizophrenia versus healthy controls
Gut Microbe Differences Linked to Schizophrenia
This systematic review and meta-analysis evaluated gut microbiota composition in individuals with schizophrenia compared to healthy controls…
A review of 48 studies finds gut bacteria patterns differ in people with schizophrenia, but key diversity measures show no clear change.
Systematic review on genetic factors in treatment-resistant schizophrenia
Genetic factors linked to treatment-resistant schizophrenia in European ancestry
This systematic review synthesizes genetic findings in treatment-resistant schizophrenia. It finds that common variants explain little liabi…
A review of 102 studies finds genetic markers are connected to treatment-resistant schizophrenia, but common variants explain little risk.
Systematic review of AI for schizophrenia prediction using medical imaging data
AI tools may help predict schizophrenia using brain scans from 185 studies
This systematic literature review examines 185 studies on artificial intelligence methodologies, including machine learning and deep learnin…
A review of 185 studies shows artificial intelligence can help identify patterns in brain scans to predict schizophrenia, offering new hope …