Research across Cancer
Related studies from across the Cancer family.
MRI Radiomics Predicts TERTp Mutation in Glioma with Moderate Accuracy
MRI Radiomics Help Predict TERTp Mutation in Glioma Patients
Meta-analysis of 14 studies shows MRI radiomics predicts TERTp mutation in glioma with AUC 0.79; combined models improve accuracy to 0.82.
New analysis shows MRI-based radiomics can help predict specific genetic mutations in glioma, potentially aiding early diagnosis and treatme…
NODI parameters ODI and V-ISO differentiate gliomas from brain metastases in contrast-enhancing regions
Brain scan technique helps tell gliomas from metastases
This meta-analysis evaluates the use of Neurite orientation dispersion and density imaging (NODDI) to distinguish gliomas from brain metasta…
A new imaging method may help doctors distinguish between gliomas and brain metastases without invasive biopsy.
Deep learning models for glioma segmentation achieve high whole tumor accuracy with DSC 0.860
New AI tools show high accuracy for mapping brain tumors before surgery
This systematic review and meta-analysis of 36 deep learning models for preoperative glioma segmentation found high whole tumor segmentation…
AI models mapped brain tumors with high accuracy, but performance varied. Training on specific datasets helped, yet no single factor fully e…
Systematic review of preclinical CBD effects in canine cancers
Lab tests suggest CBD may help treat cancer in dogs
This is a systematic review of preclinical studies on cannabidiol for canine cancers. It synthesizes evidence of antiproliferative and proap…
Lab tests suggest CBD may help treat cancer in dogs by slowing growth and triggering cell death, though human use remains unproven.
Systematic review explores metabolic-immune axis in glioma progression and resistance
Metabolic-immune link in glioma opens new treatment avenues
This systematic review synthesizes evidence on the metabolic-immune interplay in glioma. It finds that metabolic reprogramming and immune mi…
A systematic review reveals how metabolic reprogramming and immune evasion work together in glioma, pointing to new targets for therapy.
Systematic Review Links Neural Circuit Disturbances to Glioma Symptoms and Survival
Brain tumor growth linked to disrupted neural circuits
This systematic review synthesizes evidence that circuit-level disturbances in the neural microenvironment correspond with glioma-related ep…
A new review shows that glioma disrupts brain circuits, linking seizures, mood changes, and survival. Could rewiring the brain help treat tu…
Review of glioma organoid models for mechanistic discovery and therapy development
Finally Lab-Grown Brain Models Could Speed Up Glioma Treatments
This narrative review summarizes glioma organoid model systems for studying tumor-neural interactions. It concludes these models provide a f…
• Tiny lab-grown brains mimic real tumor behavior better than old methods • Kids and adults fighting deadly brain cancers like glioblastoma …
High tumour mutation burden improves overall survival in solid tumours treated with immune checkpoint inhibitors
High Mutation Counts May Predict Better Cancer Survival Outcomes
This systematic review and meta-analysis evaluated 5278 patients with solid tumours treated with immune checkpoint inhibitors or chemotherap…
High mutation counts in tumors may help predict who will survive longer when taking powerful immune-boosting cancer drugs
Narrative review explores ferroptosis-immune crosstalk in CNS diseases as therapeutic target
New hope for brain diseases by targeting a deadly cell death cycle
This narrative review synthesizes evidence on the interplay between ferroptosis and immune responses in CNS disorders including Alzheimer's,…
Scientists found a way to stop a deadly cell death cycle that makes brain diseases worse, offering new hope for patients with Alzheimer's an…
Observational study identifies four immune subtypes in newly-diagnosed glioma grades 2-4 among 354 patients
New immune map shows how glioma types affect survival chances
This primary research article describes an observational study of 354 patients with newly-diagnosed glioma grades 2-4.
A new map of immune cells in brain tumors reveals four types that predict survival and guide future treatment choices for patients.
Case report reviews capmatinib off-label use in two patients with radiation-induced MET-fusion glioma
Capmatinib Shows Promise Against Rare Brain Tumors
This case report with literature review describes off-label capmatinib use in two patients with radiation-induced gliomas harboring MET fusi…
A drug used for lung cancer is now helping some children with rare, deadly brain tumors live longer, even when standard treatments fail.
Narrative review suggests multi-omics AI models improve glioma radiotherapy response prediction over single-modality approaches
Glioma Radiotherapy Gets Smarter With Biomarker-Guided Dosing
This narrative review synthesizes evidence regarding multi-omics artificial intelligence models for predicting radiotherapy response in glio…
New biomarkers may help doctors tailor radiation doses for glioma patients, improving outcomes and reducing side effects.