Chiropractic thoracic spinal manipulation showed moderate effects on cytokines in a pilot RRMS trial
Spinal tweak lowers inflammation in MS patients
This randomized, sham-controlled pilot study enrolled 21 participants with relapsing-remitting multiple sclerosis.
A spinal tweak combined with muscle therapy lowered inflammation markers in people with multiple sclerosis, offering a new way to calm the i…
Persistent MOG-IgG titers associated with higher relapse risk in pediatric MOGAD cohort
A Simple Blood Marker Helps Predict Which Children's Brain Disease Will Return
A retrospective cohort study of 63 children with MOGAD found that persistent positive MOG-IgG titers were associated with a higher probabili…
Children with a rare brain disease whose blood test stays positive are far more likely to have repeat episodes, giving doctors a clearer way…
Respiratory muscle training improves respiratory muscle strength and pulmonary function in multiple sclerosis patients
A Simple Breathing Exercise May Strengthen a Core MS Symptom
This systematic review and meta-analysis evaluated respiratory muscle training (RMT) in 542 individuals with multiple sclerosis compared to …
Strengthening the muscles used to breathe can directly improve respiratory function for people with multiple sclerosis, offering a new layer…
Cladribine tablets maintain stable patient-reported outcomes in highly active MS over 52 weeks
Your Fitness Tracker Could Now Help Manage Your Multiple Sclerosis
An interim analysis of a prospective observational study in 190 Italian patients with highly active MS found that cladribine tablets maintai…
Multiple sclerosis patients using cladribine tablets maintain physical function while wearables track symptoms continuously between doctor v…
Sex differences in disability and demographics observed in a Swiss Multiple Sclerosis Cohort
MS Hits Men and Women Differently. Here’s What That Means for You
This cross-sectional analysis of 1,541 patients with relapsing-remitting or progressive multiple sclerosis examined sex differences in disab…
Multiple sclerosis starts earlier in women and disability builds differently in men, meaning treatment plans must account for these sex diff…
China's rehabilitation needs for neurological disorders increased significantly from 1990 to 2021
A Silent Wave of Disability is Rising. Here’s Who’s Most at Risk
This cross-sectional analysis of data from China between 1990 and 2021 examined rehabilitation needs for ten neurological conditions, includ…
China faces a rising wave of neurological disability driven by aging, with stroke, Alzheimer's, and Parkinson's creating urgent long-term ca…
FDG-PET reveals dysregulated glucose metabolism as a common feature across late-onset neurodegenerative diseases with unique patterns
FDG-PET scans show common brain glucose changes across several late-onset neurodegenerative diseases
This meta-analysis of 5,412 individuals with age-associated neurodegenerative diseases (A2ND) and 3,549 controls utilized FDG-PET to quantif…
FDG-PET scans reveal that dysregulated brain glucose metabolism is a shared feature across late-onset neurodegenerative diseases like Alzhei…
Plastic changes in brainstem reticular formation may be involved in spasticity onset across stroke and spinal cord injury
Could brainstem plastic changes trigger spasticity in stroke and spinal cord injury patients?
This systematic review examined pathophysiological similarities in spasticity among humans, primates, and rodents.
Spasticity after stroke or spinal cord injury may stem from plastic changes in the brainstem, though evidence remains limited and controvers…
Luteolin shows neuroprotective potential in preclinical models for Alzheimer's, Parkinson's, Huntington's, and multiple sclerosis
Luteolin shows potential benefits in early studies for neurodegenerative diseases
This review of preclinical studies and preliminary clinical observations suggests luteolin may reduce neuroinflammation and improve function…
Luteolin may help slow brain decline in Alzheimer's and Parkinson's by calming inflammation and boosting antioxidant defenses in early studi…
Normative MRI modelling identifies critical brain volume deviations associated with disability in multiple sclerosis
Do brain scans show more warning signs of disability in multiple sclerosis than in healthy people?
This observational cohort study applied a normative model trained on 62,444 healthy MRI datasets to scans from 362 people with multiple scle…
Brain scans reveal that people with multiple sclerosis have more critical volume deviations than healthy individuals, directly linked to hig…
High-dose melatonin linked to hepatotoxicity in small PP-MS trial, prompting early halt
High-dose melatonin trial halted after liver safety concerns in MS patients
A phase I/II RCT of 8 patients with PP-MS on stable ocrelizumab found that adjunctive high-dose oral melatonin (300 mg/day) was associated w…
A high-dose melatonin trial for multiple sclerosis stopped early after three of four patients developed mild liver injury, though the issue …
CSF proteomic signatures show potential for MS diagnosis and prognosis in cohort study
Could a spinal fluid test predict how multiple sclerosis will progress?
A multicentric cohort study of 120 patients with multiple sclerosis, clinically isolated syndrome, and healthy controls analyzed cerebrospin…
A spinal fluid test with ten proteins could predict multiple sclerosis progression, showing promise for forecasting disease activity up to f…