Demyelinating Autoimmune Diseases, CNS

All Demyelinating Autoimmune Diseases, CNS Articles

• Narrative review discusses MS continuum concepts for high-risk individuals
• Network meta-analysis finds acupoint stimulation may improve function and fatigue in multiple sclerosis
• Review of SC-EVs for SLE and MS highlights immunomodulatory mechanisms and neuroprotective potential
• Narrative review discusses jump assessment for multiple sclerosis disability evaluation
• Ocrelizumab treatment in multiple sclerosis shows disability improvement in relapsing forms
• Narrative review discusses CAR-T and HSC therapies for cancer and autoimmune conditions
• Systematic review and meta-analysis finds 30.2% success rate for MVD in TN-MS patients
• Global MS burden in women of childbearing age rises 48% from 1990 to 2021
• Narrative review explores ferroptosis-immune crosstalk in CNS diseases as therapeutic target
• Review of active therapeutic interventions in 255 people with multiple sclerosis undergoing inpatient rehabilitation
• Frexalimab study validates PROMIS-Fatigue-MS-8a and MSIS-29v2 in relapsing multiple sclerosis patients
• Aerobic and strength training reduce fatigue in multiple sclerosis patients
• Laughter yoga reduced fatigue in people with multiple sclerosis in a randomized controlled trial
• Exercise training improves cognition and fatigue in older adults with multiple sclerosis
• Meta-analysis finds PLISSIT counseling improves sexual life in women with MS
• Sleep efficiency improved with mindfulness in multiple sclerosis patients according to a meta-analysis
• Meta-analysis shows reduced stress-induced autonomic responses in people with multiple sclerosis compared to controls
• Case report and literature review of severe adverse reactions following pucotenlimab treatment
• Narrative review discusses multi-target strategies for multiple sclerosis progression
• Mini-review explores oxidized mannan-conjugated MOG peptide for multiple sclerosis immunotherapy
• Plasma cytokines and CSF ROS measured in MS phenotypes show associations with disability and cognition
• Composite Endpoints Show Weaker Treatment Effects Than EDSS Alone in Multiple Sclerosis Trials
• Narrative review notes lack of comprehensive synthesis on antioxidant strategies for multiple sclerosis
• Simulation study of frontier AI models analyzing 10,000 synthetic Multiple Sclerosis cases reveals variable diagnostic safety
• Observational study finds lower delayed recall ratios in multiple sclerosis patients versus controls
• Systematic review and meta-analysis of CBT for depression in multiple sclerosis patients
• Narrative review examines resveratrol in Alzheimer's, Parkinson's, MS, and cerebral ischemia with noted limitations
• Observational study abstract reports AI RNA sequencing diagnostic accuracy in multiple sclerosis and neuromyelitis optica
• Higher serum MOG protein levels associated with MS diagnosis and disease activity compared to controls
• Switching therapy after rituximab resistance in AQP4-IgG+ NMOSD shows variable relapse outcomes
• Elevated CSF and blood sCD27 associated with autoimmune disease in severe psychiatric disorders and MS
• Phase 1b trial of intravenous B001 shows favorable safety in aquaporin-4-positive NMOSD patients
• Narrative review explores multimodal approaches for autoimmune diseases including rheumatoid arthritis and Crohn's
• Narrative review of animal models in neuromyelitis optica spectrum disorder pathogenesis
• Oral cladribine reshapes CSF immune cell composition in relapsing multiple sclerosis
• Protocol for pilot RCT of neuromodulation-augmented balance training in ambulatory people with multiple sclerosis
• EBV DNA positivity links to MS risk genes in a cross-ancestry study of 617,186 participants
• Real-world cohort examines Alemtuzumab effects on bowel/bladder function and latent progressive trajectories in MS patients
• MRI outcomes show weak association with disability in primary progressive multiple sclerosis patients
• Systematic Review Examines T-Cell Mechanisms and Therapies in Multiple Sclerosis
• 6-week multimodal exercise training feasible for frail people with multiple sclerosis in pilot RCT
• Meta-analysis finds respiratory muscle training improves some lung function measures in multiple sclerosis
• REDDI pipeline improves balanced accuracy for classifying MCI, MS, Parkinson's, and ALS using MEG data
• Home-based e-based exercise protocol feasibility study for patients with multiple sclerosis and comorbidities
• Rituximab exposure is associated with serum sickness in patients with multiple sclerosis, nephrotic syndrome, or immune thrombocytopenia
• Chiropractic thoracic spinal manipulation showed moderate effects on cytokines in a pilot RRMS trial
• Network meta-analysis of six exercise modalities in females with multiple sclerosis shows improvements in fatigue, quality of life, balance, depression, and mental health
• Dimethyl fumarate with slow titration improves treatment satisfaction and quality of life in Iranian MS patients
• Persistent MOG-IgG titers associated with higher relapse risk in pediatric MOGAD cohort
• Cladribine tablets maintain stable patient-reported outcomes in highly active MS over 52 weeks
• Sex differences in disability and demographics observed in a Swiss Multiple Sclerosis Cohort
• Respiratory muscle training improves respiratory muscle strength and pulmonary function in multiple sclerosis patients
• China's rehabilitation needs for neurological disorders increased significantly from 1990 to 2021
• Luteolin shows neuroprotective potential in preclinical models for Alzheimer's, Parkinson's, Huntington's, and multiple sclerosis
• Normative MRI modelling identifies critical brain volume deviations associated with disability in multiple sclerosis
• FDG-PET reveals dysregulated glucose metabolism as a common feature across late-onset neurodegenerative diseases with unique patterns
• Plastic changes in brainstem reticular formation may be involved in spasticity onset across stroke and spinal cord injury
• CSF proteomic signatures show potential for MS diagnosis and prognosis in cohort study
• High-dose melatonin linked to hepatotoxicity in small PP-MS trial, prompting early halt
• FDA Approves Kesimpta (ofatumumab) for Relapsing Forms of Multiple Sclerosis in Adults
• Online behavioral intervention increases physical activity and improves depression in newly diagnosed multiple sclerosis
• Neuromuscular electrostimulation plus swallowing therapy may benefit dysphagia in severely disabled MS patients
• Percutaneous balloon compression shows initial pain relief in multiple sclerosis-related trigeminal neuralgia
• Ponesimod Shows Sustained Efficacy and Safety in RMS Over 5 Years