Temperature-guided preventive care reduces recurrence risk in patients with diabetic foot ulcers
Temperature Monitoring May Reduce Recurrence of Diabetic Foot Ulcers
This meta-analysis evaluated the impact of temperature-guided preventive care compared to standard care for individuals at high risk for dia…
Monitoring skin temperature may help prevent the return of diabetic foot ulcers in high-risk patients, potentially improving long-term care …
Chronic hyperglycemia causes multi-level nerve damage across the peripheral, autonomic, and central nervous systems
Understanding how high blood sugar damages the entire nervous system in diabetes
This narrative review synthesizes how chronic hyperglycemia impacts the entire neuroaxis in patients with diabetes. It details metabolic and…
High blood sugar can damage nerves throughout the whole body. This affects your senses, movement, and internal organs.
Review of ADSC-Exos for diabetic foot ulcers lacks reported efficacy data or safety outcomes in this narrative synthesis
Stem cell exosomes may help heal diabetic foot ulcers
This narrative review addresses the use of adipose-derived stem cell exosomes for diabetic foot ulcers and diabetes. The authors note that k…
A review suggests that exosomes from stem cells could improve healing for diabetic foot ulcers, offering a new treatment option.
Network meta-analysis reveals placenta-derived products significantly improve diabetic foot ulcer healing rates versus standard care options
New topical treatments show strong promise for healing diabetic foot ulcers
A comprehensive network meta-analysis of 6,161 patients demonstrates that twelve topical therapies enhance wound healing in diabetic foot ul…
A major analysis of 6,161 patients found that 12 topical therapies significantly improved wound healing rates compared to standard care for …
Network meta-analysis ranks debridement strategies for venous and diabetic ulcers
Biological debridement ranks highest for healing chronic leg wounds in new analysis
Biological debridement ranked highest for wound healing and complete debridement in a network meta-analysis of 25 RCTs. Enzymatic and autoly…
Biological debridement shows the highest chance of healing wounds, but experts warn the evidence has gaps and needs careful reading.
Meta-analysis finds very uncertain evidence for CO therapy in wound healing
Carbon Dioxide Therapy May Help Stubborn Wounds Heal Faster
This meta-analysis of 127 wounds/participants evaluated highly concentrated carbon dioxide therapy for diabetic foot ulcers and pressure inj…
A new review suggests highly concentrated carbon dioxide therapy may help chronic wounds heal better, but the evidence is still early.
Topical pyroligneous extract hydrogel may improve wound shrinkage in diabetic foot ulcers
New gel may help heal diabetic foot ulcers faster than standard care
This first-in-human randomized controlled trial enrolled sixteen volunteers with diabetic foot ulcers.
A new gel with plant extract showed faster healing and fewer infections in people with diabetic foot ulcers during this first-in-human trial…
Bayesian network meta-analysis of seven debridement approaches for diabetic foot ulcers shows low certainty evidence
New data ranks debridement methods for healing diabetic foot ulcers faster
This Bayesian network meta-analysis evaluated seven debridement approaches versus standard wound care for individuals with diabetic foot ulc…
New research shows biological and enzymatic debridement methods shrink diabetic foot ulcers the most, but experts warn the evidence is not y…
Systematic review and meta-analysis shows antifungal resistance rates vary in diabetic foot ulcer patients
Antifungal resistance high in diabetic foot ulcers
This systematic review and meta-analysis evaluated antifungal resistance in patients with diabetic foot ulcers.
Many diabetic foot ulcer infections resist common antifungals, especially nystatin and itraconazole.
Bibliometric analysis reveals increasing research trends in intestinal microbiota and chronic wounds
Research shows gut health may help heal chronic wounds
This bibliometric analysis of 553 English articles examines research trends regarding intestinal microbiota and chronic wounds from 2005 to …
New research trends suggest that the bacteria in your gut could play a vital role in healing difficult wounds like diabetic foot ulcers.
C-reactive protein-to-albumin ratio predicts 6-month major adverse limb events in hospitalized diabetic foot ulcer patients
One Blood Test Could Save Diabetic Feet From Amputation
This retrospective cohort study of 139 hospitalized patients with diabetic foot ulcers at a regional referral center in Northwest China eval…
New blood test ratio helps doctors predict which diabetic foot ulcers might lead to amputation or death within six months.
Retrospective cohort study assesses diagnostic accuracy for Wagner Grade ≥2 DFUs in hospitalized type 2 diabetes patients
New Tool Predicts Severe Foot Ulcers in Diabetic Patients Before They Worsen
This retrospective cohort study evaluated diagnostic accuracy for Wagner Grade ≥2 diabetic foot ulcers (DFUs) in 510 hospitalized patients w…
This new calculator could help doctors spot dangerous foot ulcers in diabetic patients sooner, giving them a chance to act before it’s too l…
Research across Diabetes
Related studies from across the Diabetes family.
Early subcutaneous basal insulin plus IV insulin reduces time to DKA resolution by 4.06 hours
Early Subcutaneous Insulin Shortens Recovery Time for Diabetic Ketoacidosis
This meta-analysis of randomized controlled trials evaluated adding early subcutaneous basal insulin to intravenous insulin for adults with …
Adding early subcutaneous insulin to IV treatment can speed up recovery for patients with diabetic ketoacidosis without increasing safety ri…
Fluocinolone Acetonide Implant Shows Reduced Injection Frequency for Diabetic Macular Edema
Fluocinolone Acetonide Implant May Reduce Injection Frequency for DME
A Phase 4 trial shows fluocinolone acetonide implants achieve similar visual outcomes to aflibercept with significantly fewer total injectio…
A new eye implant for diabetic macular edema may significantly reduce the number of monthly injections needed to maintain vision.
miR-29a-3p and miR-204-5p are downregulated in diabetic nephropathy as potential biomarker candidates
Specific MicroRNA Signatures Linked to Type 1 Diabetes Complications
This systematic review and meta-analysis of 9 studies involving 34 contrasts identified specific circulating miRNA signatures associated wit…
Researchers identified specific microRNA signals that may help track kidney and eye damage in patients with Type 1 Diabetes.
Immunometabolic dysregulation drives hyperalgesia and hypoesthesia in diabetic peripheral neuropathy
New research explores how inflammation drives nerve damage in diabetes
This narrative review explores the pathophysiology of diabetic peripheral neuropathy, focusing on how hyperglycemia, lipotoxicity, and intes…
Chronic high blood sugar causes more than just high glucose; it triggers a cycle of inflammation and immune stress that damages nerves.
Intravitreal ziv-aflibercept reduces central macular thickness and improves visual acuity in DME and RVO
Trial shows ziv-aflibercept improves vision in macular edema cases
This systematic review and meta-analysis of 5 RCTs and 8 observational studies found that intravitreal ziv-aflibercept significantly reduced…
A new eye treatment called ziv-aflibercept may help reduce swelling and improve vision for patients with specific types of macular edema.
Local antibiotic delivery systems increase healing rates in diabetic foot osteomyelitis compared with control groups in this meta-analysis
Local Antibiotics May Boost Healing in Diabetic Foot Infections
This systematic review and meta-analysis evaluated local antibiotic delivery systems versus control groups for patients with diabetic foot o…
A new analysis suggests local antibiotic delivery may improve healing for diabetic foot bone infections, but more research is needed.
Antibiotic cement achieves 85.2% healing rate in diabetic foot osteomyelitis meta-analysis
Antibiotic cement may help heal diabetic foot infections without major surgery
A systematic review and meta-analysis of 82 patients with diabetic foot osteomyelitis found a weighted healing rate of 85.2% with antibiotic…
A meta-analysis suggests antibiotic-impregnated cement can heal diabetic foot osteomyelitis in most patients, though some still need surgery…
SGLT2 inhibitor use associated with increased diabetic ketoacidosis risk, especially with elevated HbA1c
New review shows SGLT2 drugs raise DKA risk when blood sugar is high
This meta-analysis of observational and randomized trials found SGLT2 inhibitor use is associated with an increased risk of diabetic ketoaci…
A big review of many studies found that medicines for diabetes called SGLT2 inhibitors can increase the chance of a serious condition called…
Perioperative anti-VEGF injections improve vision and reduce bleeding in proliferative diabetic retinopathy
Anti-VEGF injections before eye surgery improve vision and reduce bleeding in diabetic retinopathy
This network meta-analysis evaluated the timing of perioperative anti-VEGF injections for proliferative diabetic retinopathy. Results indica…
A network meta-analysis of 2,646 eyes found that perioperative anti-VEGF injections improved vision and reduced bleeding in patients with pr…
Exosomes show promise as biomarkers and therapeutic vectors in diabetic complications
Review suggests exosomes may help target multiple diabetes complications
This narrative review explores the role of exosomes in diabetic kidney disease, retinopathy, and peripheral neuropathy. It highlights their …
A narrative review suggests exosomes might inform strategies to target multiple diabetes complications together, though clinical standardiza…
Scoping review maps burden of diabetic emergencies in African healthcare settings
Diabetic emergencies in Africa show wide variation in rates and outcomes
This scoping review synthesizes data from 25 studies regarding diabetic emergencies in Africa. The authors report wide variation in reported…
A review of 25 studies finds diabetic emergencies in Africa vary widely, with high death rates and long hospital stays.
Review of 16 cases shows 25% mortality for pulmonary mucormycosis in DKA patients treated with amphotericin B
Treatment for rare lung infection kills one in four patients with diabetic ketoacidosis
This case report and literature review synthesizes data from 16 patients with diabetic ketoacidosis complicated by invasive pulmonary mucorm…
A review of 16 patients found that one in four died from this rare lung infection. Early diagnosis and surgery are key.
All diabetic neuropathy Articles
- Temperature-guided preventive care reduces recurrence risk in patients with diabetic foot ulcers
- Chronic hyperglycemia causes multi-level nerve damage across the peripheral, autonomic, and central nervous systems
- Review of ADSC-Exos for diabetic foot ulcers lacks reported efficacy data or safety outcomes in this narrative synthesis
- Network meta-analysis ranks debridement strategies for venous and diabetic ulcers
- Network meta-analysis reveals placenta-derived products significantly improve diabetic foot ulcer healing rates versus standard care options
- Meta-analysis finds very uncertain evidence for CO therapy in wound healing
- Bayesian network meta-analysis of seven debridement approaches for diabetic foot ulcers shows low certainty evidence
- Topical pyroligneous extract hydrogel may improve wound shrinkage in diabetic foot ulcers
- Systematic review and meta-analysis shows antifungal resistance rates vary in diabetic foot ulcer patients
- Bibliometric analysis reveals increasing research trends in intestinal microbiota and chronic wounds
- C-reactive protein-to-albumin ratio predicts 6-month major adverse limb events in hospitalized diabetic foot ulcer patients
- Retrospective cohort study assesses diagnostic accuracy for Wagner Grade ≥2 DFUs in hospitalized type 2 diabetes patients
- Prospective observational cohort evaluates Tardivo Algorithm risk stratification and outcomes in diabetic foot patients
- BOPPPS instruction improves vascular surgery resident outcomes in diabetic foot ulcer training compared to traditional methods
- Silver/copper nanoparticle dressing shows greater wound reduction than ionic silver in infected diabetic foot ulcers
- Autologous cell therapy improved healing rates and reduced ulcer area in patients with diabetic foot ulcers compared to control
- Higher UACR associates with Gram-negative dominance and worse inflammation in diabetic foot infections
- Posterior slab cast shows higher healing rate than total contact cast for diabetic foot ulcers in single-center RCT
- Minimal offloading dressing shows similar healing rates to felted foam for plantar diabetic foot ulcers in pilot trial