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Diabetic neuropathy

Part of Diabetes

Subtypes of Diabetic neuropathy

Diabetic Foot Ulcers 19 Diabetic foot 5

28 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for diabetic neuropathy

16 trials tracked for diabetic neuropathy: 8 in phase 3 or 4.

16Trials tracked
8Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 4 4 Phase 3 4 Phase 2 5 Phase 1 1 Other / NA 2
  1. Phase 4 Lovaza® and Microvascular Function in Type 2 Diabetes Completed
  2. Phase 4 Alpha Lipoic Acid for Treatment of Diabetic Neuropathy Completed
  3. Phase 4 A Randomized Double-Blind Study Testing the Effects of Pregabalin on Diabetic Neuropathy Completed
  4. Phase 4 A Study to Compare Safety and Efficacy of Tramadol Hydrochloride/Acetaminophen With Gabapentin in Participants With Diabetic Neuropathy Completed
  5. Phase 3 An Evaluation of the Efficacy and Safety of E2007 in Patients With Painful Diabetic Neuropathy Completed
  6. Phase 3 A Follow-On Trial to Assess the Long Term Safety and Efficacy of SPM 927 in Painful Distal Diabetic Neuropathy Completed
Show 10 more trials
  1. Phase 3 A Study of Sativex® for Pain Relief Due to Diabetic Neuropathy Completed
  2. Phase 3 A Safety and Efficacy Study for Tapentadol (CG5503) Extended Release for Patients With Painful Diabetic Peripheral Neuropathy Completed
  3. Phase 2 The Efficacy and Safety of Clonidine Hydrochloride Topical Gel, vs Clonidine Hydrochloride Gel Comparator to Treat Painful Diabetic Neuropathy Completed
  4. Phase 2 A Study In Patients With Neuropathic Pain From Diabetic Peripheral Neuropathy (DPN) Completed
  5. Phase 2 Study of DA-9801 to Treat Diabetic Neuropathy Completed
  6. Phase 2 Study of Clonidine Hydrochloride Topical Gel, 0.1% in the Treatment of Pain Associated With Diabetic Neuropathy Completed
  7. Phase 2 Study to Evaluate the Analgesic Efficacy of 28 Days' Oral Administration of AZD2066 Compared With Placebo in Patients With Painful Diabetic Neuropathy Completed
  8. Phase 1 Neuropathic Pain Syndrome Patient Study (MK-0000-072) Completed
  9. N/A Exercise-facilitated Neurorehabilitation in Diabetic Neuropathy Completed
  10. N/A Clinical Efficacy and Human Factors Validation Testing of the Erchonia EVRL for Providing Temporary Relief of Diabetic Peripheral Neuropathy Foot Pain Completed

Showing the 16 most-cited and recently-updated of 16 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Diabetes

Related studies from across the Diabetes family.

GLP-1 receptor agonists are not associated with increased diabetic macular edema risk in real-world data
Ophthalmology Meta-analysis
GLP-1 receptor agonists are not associated with increased diabetic macular edema risk in real-world data Comparing Eye Health Risks Between Different Types of Diabetes Medications
This meta-analysis of real-world data indicates that GLP-1 receptor agonists are not associated with an increased risk of diabetic macular e…
New data looks at how GLP-1 medications affect eye health in people with diabetes compared to other common treatments.
Biosimilar anti-VEGF agents show comparable visual outcomes and safety to reference anti-VEGF agents
Ophthalmology Meta-analysis
Biosimilar anti-VEGF agents show comparable visual outcomes and safety to reference anti-VEGF agents Biosimilar drugs show similar results for several retinal diseases
This systematic review and meta-analysis evaluates biosimilar anti-VEGF agents compared to reference products for several retinal diseases. …
New data shows that biosimilar drugs perform as well as brand name drugs for patients with several types of vision-threatening eye condition…
Intravitreal ranibizumab improves visual acuity and reduces macular thickness more than laser photocoagulation
Ophthalmology Meta-analysis
Intravitreal ranibizumab improves visual acuity and reduces macular thickness more than laser photocoagulation Ranibizumab Shows Better Vision Results Than Laser for Macular Edema
This meta-analysis of 1,040 patients with diabetic macular edema found that intravitreal ranibizumab significantly improved best corrected v…
A review of data shows that ranibizumab may improve vision and reduce swelling more than laser treatment for patients with diabetic macular …
Tripterygium glycosides provide renal protective effects in animal models of diabetic nephropathy
Drug Pipeline Meta-analysis
Tripterygium glycosides provide renal protective effects in animal models of diabetic nephropathy Tripterygium glycosides show potential to protect kidneys in diabetes
This meta-analysis of preclinical animal models indicates that tripterygium glycosides (TGs) significantly reduce markers of renal dysfuncti…
New research on animal models suggests tripterygium glycosides may protect kidneys from damage caused by diabetes, but specific dosing is cr…
DEKODE platform protocol aims to improve clinical and process outcomes in diabetic ketoacidosis
Diabetes & Endocrinology Guideline
DEKODE platform protocol aims to improve clinical and process outcomes in diabetic ketoacidosis New Digital System Aims to Improve Diabetic Ketoacidosis Care
This guideline outlines a study protocol for the DEKODE platform, a cloud-based audit-and-feedback system for managing diabetic ketoacidosis…
A new digital audit system aims to standardize care and improve outcomes for patients experiencing diabetic ketoacidosis in hospital setting…
Press needle and plum-blossom needle combination significantly lowers pro-inflammatory cytokines in diabetic peripheral neuropathy
Diabetes & Endocrinology RCT
Press needle and plum-blossom needle combination significantly lowers pro-inflammatory cytokines in diabetic peripheral neuropathy Acupuncture Techniques May Improve Nerve Function in Diabetic Patients
This randomized controlled trial of 225 patients with diabetic peripheral neuropathy found that press needle embedding combined with plum-bl…
A new trial suggests that specific acupuncture techniques may lower inflammation and improve nerve conduction in people with diabetic periph…
SGLT2 inhibitors reduce risk of diabetic retinopathy progression (rr 0.77) and macular edema progression (rr 0.75)
Ophthalmology Meta-analysis
SGLT2 inhibitors reduce risk of diabetic retinopathy progression (rr 0.77) and macular edema progression (rr 0.75) SGLT2 inhibitors show promise in slowing diabetic eye disease
This meta-analysis of 1,785,409 patients with established diabetic retinopathy (DR) or diabetic macular edema (DME) found that SGLT2i therap…
A large analysis suggests SGLT2 inhibitors may slow the progression of vision-threatening complications in people with diabetes.
Mass spectrometry identifies 681 differentially expressed proteins in patients with proliferative diabetic retinopathy
Ophthalmology Meta-analysis
Mass spectrometry identifies 681 differentially expressed proteins in patients with proliferative diabetic retinopathy Proteomics Analysis Identifies Key Proteins in Diabetic Retinopathy
This meta-analysis of proteomics data using mass spectrometry identified 681 differentially expressed proteins in patients with proliferativ…
New research identifies specific proteins and biological pathways linked to proliferative diabetic retinopathy to help guide future medical …
Higher Triglyceride-glucose index is associated with increased risk of diabetic peripheral neuropathy
Diabetes & Endocrinology Meta-analysis
Higher Triglyceride-glucose index is associated with increased risk of diabetic peripheral neuropathy High Triglyceride and Glucose Levels Linked to Nerve Damage in Diabetes
This meta-analysis of 32,281 patients with Type 2 Diabetes found that a higher TyG index is associated with an increased risk of diabetic pe…
High levels of fats and sugars in the blood can significantly increase the risk of nerve damage for people with type 2 diabetes.
rs741301 polymorphism is associated with reduced susceptibility to diabetic nephropathy in meta-analysis
Diabetes & Endocrinology Meta-analysis
rs741301 polymorphism is associated with reduced susceptibility to diabetic nephropathy in meta-analysis Genetic Marker Linked to Lower Risk of Diabetic Kidney Disease
This meta-analysis of 880 individuals with diabetes mellitus and 1008 individuals with diabetic nephropathy found that the rs741301 polymorp…
A specific genetic variation, known as the rs741301 polymorphism, may be linked to a lower risk of developing kidney damage in people with d…
Moxibustion Combination Therapies Improve Nerve Conduction and Clinical Scores in Diabetic Neuropathy
Diabetes & Endocrinology Meta-analysis
Moxibustion Combination Therapies Improve Nerve Conduction and Clinical Scores in Diabetic Neuropathy Moxibustion combinations may improve nerve function in diabetic neuropathy
A network meta-analysis suggests moxibustion combined with herbal medicine or acupuncture may improve nerve conduction and clinical scores i…
Combining moxibustion with herbal medicine or acupuncture may improve nerve conduction and scores for people with diabetic peripheral neurop…
Ranibizumab port delivery system shows noninferior BCVA gains and low supplemental treatment requirements in diabetic retinopathy
Oncology Meta-analysis
Ranibizumab port delivery system shows noninferior BCVA gains and low supplemental treatment requirements in diabetic retinopathy Ranibizumab port delivery system shows promise for diabetic eye conditions
This meta-analysis evaluates the ranibizumab port delivery system (PDS) for patients with diabetic retinopathy and diabetic macular edema. T…
A new delivery system for ranibizumab shows consistent results for patients with diabetic retinopathy and macular edema.

All diabetic neuropathy Articles