Topical pyroligneous extract hydrogel may improve wound shrinkage in diabetic foot ulcers
New gel may help heal diabetic foot ulcers faster than standard care
This first-in-human randomized controlled trial enrolled sixteen volunteers with diabetic foot ulcers.
A new gel with plant extract showed faster healing and fewer infections in people with diabetic foot ulcers during this first-in-human trial…
Bayesian network meta-analysis of seven debridement approaches for diabetic foot ulcers shows low certainty evidence
New data ranks debridement methods for healing diabetic foot ulcers faster
This Bayesian network meta-analysis evaluated seven debridement approaches versus standard wound care for individuals with diabetic foot ulc…
New research shows biological and enzymatic debridement methods shrink diabetic foot ulcers the most, but experts warn the evidence is not y…
Systematic review and meta-analysis shows antifungal resistance rates vary in diabetic foot ulcer patients
Antifungal resistance high in diabetic foot ulcers
This systematic review and meta-analysis evaluated antifungal resistance in patients with diabetic foot ulcers.
Many diabetic foot ulcer infections resist common antifungals, especially nystatin and itraconazole.
Bibliometric analysis reveals increasing research trends in intestinal microbiota and chronic wounds
Research shows gut health may help heal chronic wounds
This bibliometric analysis of 553 English articles examines research trends regarding intestinal microbiota and chronic wounds from 2005 to …
New research trends suggest that the bacteria in your gut could play a vital role in healing difficult wounds like diabetic foot ulcers.
C-reactive protein-to-albumin ratio predicts 6-month major adverse limb events in hospitalized diabetic foot ulcer patients
One Blood Test Could Save Diabetic Feet From Amputation
This retrospective cohort study of 139 hospitalized patients with diabetic foot ulcers at a regional referral center in Northwest China eval…
New blood test ratio helps doctors predict which diabetic foot ulcers might lead to amputation or death within six months.
Retrospective cohort study assesses diagnostic accuracy for Wagner Grade ≥2 DFUs in hospitalized type 2 diabetes patients
New Tool Predicts Severe Foot Ulcers in Diabetic Patients Before They Worsen
This retrospective cohort study evaluated diagnostic accuracy for Wagner Grade ≥2 diabetic foot ulcers (DFUs) in 510 hospitalized patients w…
This new calculator could help doctors spot dangerous foot ulcers in diabetic patients sooner, giving them a chance to act before it’s too l…
BOPPPS instruction improves vascular surgery resident outcomes in diabetic foot ulcer training compared to traditional methods
New teaching method improved test scores for vascular surgery residents in diabetic foot care training
This retrospective cohort study evaluated 196 vascular surgery residents at Xuanwu Hospital, Capital Medical University.
A new teaching method helped vascular surgery residents score higher on exams and perform better in diabetic foot care skills.
Prospective observational cohort evaluates Tardivo Algorithm risk stratification and outcomes in diabetic foot patients
What does a new risk tool mean for people with diabetic foot problems?
This prospective observational cohort study included 42 adult patients with diabetic foot in a vascular surgery outpatient setting.
A new risk tool tracked healing in 42 diabetic foot patients, showing 94% kept their limbs and wounds healed in about five months during rou…
Autologous cell therapy improved healing rates and reduced ulcer area in patients with diabetic foot ulcers compared to control
Using your own cells to heal stubborn diabetic foot wounds
This meta-analysis and systematic review evaluated autologous cell therapy versus control in 2,214 patients with diabetic foot ulcers.
Using a patient's own cells to jump-start healing may close diabetic foot ulcers that regular treatment leaves open for months.
Silver/copper nanoparticle dressing shows greater wound reduction than ionic silver in infected diabetic foot ulcers
Small pilot study finds silver-copper dressing may reduce wound size in diabetic foot ulcers
A small pilot RCT of 30 patients with infected diabetic foot ulcers compared silver/copper nanoparticle dressings to ionic silver dressings.
A new silver-copper dressing shrank infected diabetic foot ulcers by 43% in just one week, outperforming standard silver dressings in a smal…
Higher UACR associates with Gram-negative dominance and worse inflammation in diabetic foot infections
A Simple Urine Test Could Predict Your Diabetic Foot Infection
This retrospective cross-sectional observational study evaluated 325 diabetic foot infection patients from a northern Chinese tertiary hospi…
A common check for kidney health may also act as a crystal ball for foot infections, helping doctors pick the winning antibiotic from the st…
Posterior slab cast shows higher healing rate than total contact cast for diabetic foot ulcers in single-center RCT
Posterior slab cast may heal diabetic foot ulcers faster than total contact cast in small trial
A single-center, open-label RCT of 99 adults with Type 2 diabetes and plantar diabetic foot ulcers compared posterior slab cast (PSC) to tot…
A new cast type helped more diabetic foot wounds heal in six months compared to the standard method in a small trial.
Research across Diabetes
Related studies from across the Diabetes family.
Euonymus alatus may improve glucose metabolism and reduce urinary protein in diabetic nephropathy
Plant extract shows promise in managing diabetes and kidney health
This systematic review of preclinical and clinical data indicates that Euonymus alatus may lower blood glucose, reduce urinary protein, and …
A review of the plant Euonymus alatus suggests it may lower blood sugar and protect kidneys in people with diabetes.
Pharmacist-led medication therapy management improves adherence and glycemic control in a patient with complex T2DM
Pharmacist-led care improves blood sugar for woman with long-term diabetes
This case report describes a single patient with type 2 diabetes who received pharmacist-led medication therapy management. The intervention…
A pharmacist-led review helped a woman with a 30-year history of Type 2 Diabetes significantly improve her medication adherence and blood su…
Intravenous alpha-lipoic acid optimizes symptom relief while oral administration supports structural repair in DPN
Different ways to give alpha-lipoic acid help diabetic nerve pain
This Bayesian network meta-analysis evaluates various alpha-lipoic acid (ALA) administration routes for diabetic peripheral neuropathy. Find…
New data shows that intravenous and oral versions of alpha-lipoic acid offer different benefits for managing symptoms and repairing nerves i…
Microvascular alteration is a statistically significant determinant for diabetic peripheral neuropathy prevalence
New data reveals key drivers of nerve damage in diabetes
This meta-analysis of 83,560 patients across 24 countries identified a global diabetic peripheral neuropathy (DPN) prevalence of 57.42% (95%…
Over half of people with diabetes suffer from nerve damage, but new data highlights specific blood vessel changes as a primary driver of the…
Nerve decompressive surgery of the lower limbs reduces pain scores in patients with diabetic peripheral neuropathy
Nerve surgery may reduce pain for patients with diabetic neuropathy
This meta-analysis of 7 trials involving 207 patients found that nerve decompressive surgery of the lower limbs (NDSLL) significantly reduce…
New analysis shows nerve decompression surgery can lower pain scores for some people with diabetic peripheral neuropathy.
AI-OCT reports reduced false-positive DME referral rates from 69.1% to 24.1%
AI technology reduces unnecessary referrals for diabetic macular edema
This randomized clinical trial evaluated the impact of AI-OCT reports on identifying diabetic macular edema (DME) in patients with diabetes.…
New research shows that adding AI-powered imaging can significantly cut down on false alarms when screening patients for eye issues caused b…
Vitamin D supplementation shows low certainty reductions in urinary markers for diabetic kidney disease
Vitamin D shows limited benefit for diabetic kidney disease
This umbrella review meta-analysis evaluates vitamin D and its analogs in patients with diabetic kidney disease. While some reduction in uri…
Vitamin D may lower protein in urine for diabetic kidney disease, but evidence is weak and no benefit for kidney function or survival.
Balanced crystalloids reduce time to DKA resolution by 1.60 hours compared to 0.9% saline
Balanced Crystalloids May Speed Recovery in Pediatric Diabetic Ketoacidosis
This meta-analysis of 320 pediatric patients with diabetic ketoacidosis found that balanced crystalloids significantly reduced the time to D…
A review of data suggests balanced crystalloid fluids may resolve diabetic ketoacidosis faster than standard saline in children.
Early subcutaneous basal insulin plus IV insulin reduces time to DKA resolution by 4.06 hours
Early Subcutaneous Insulin Shortens Recovery Time for Diabetic Ketoacidosis
This meta-analysis of randomized controlled trials evaluated adding early subcutaneous basal insulin to intravenous insulin for adults with …
Adding early subcutaneous insulin to IV treatment can speed up recovery for patients with diabetic ketoacidosis without increasing safety ri…
Fluocinolone Acetonide Implant Shows Reduced Injection Frequency for Diabetic Macular Edema
Fluocinolone Acetonide Implant May Reduce Injection Frequency for DME
A Phase 4 trial shows fluocinolone acetonide implants achieve similar visual outcomes to aflibercept with significantly fewer total injectio…
A new eye implant for diabetic macular edema may significantly reduce the number of monthly injections needed to maintain vision.
miR-29a-3p and miR-204-5p are downregulated in diabetic nephropathy as potential biomarker candidates
Specific MicroRNA Signatures Linked to Type 1 Diabetes Complications
This systematic review and meta-analysis of 9 studies involving 34 contrasts identified specific circulating miRNA signatures associated wit…
Researchers identified specific microRNA signals that may help track kidney and eye damage in patients with Type 1 Diabetes.
Immunometabolic dysregulation drives hyperalgesia and hypoesthesia in diabetic peripheral neuropathy
New research explores how inflammation drives nerve damage in diabetes
This narrative review explores the pathophysiology of diabetic peripheral neuropathy, focusing on how hyperglycemia, lipotoxicity, and intes…
Chronic high blood sugar causes more than just high glucose; it triggers a cycle of inflammation and immune stress that damages nerves.