Research across Cancer
Related studies from across the Cancer family.
Narrative review on vitamin D and VDR in gastrointestinal and pulmonary diseases
Vitamin D's Role in Gut and Lung Health Examined
This narrative review synthesizes evidence on vitamin D deficiency and VDR expression across gastrointestinal and pulmonary conditions. The …
A review explores how vitamin D deficiency and VDR expression may influence digestive and respiratory diseases, but more research is needed.
Meta-analysis finds sex-based differences in ICI survival benefit for advanced gastroesophageal cancer
Immunotherapy Works Differently for Men and Women with Stomach Cancer
This meta-analysis of 15 RCTs examined immune-checkpoint inhibition for advanced gastroesophageal cancer. It found a significant overall sur…
Men with esophageal cancer gain a clear survival edge from immunotherapy, while women do not, but both sexes benefit similarly in stomach ca…
FDA Approves Enhertu (fam-trastuzumab deruxtecan-nxki) for Multiple HER2-Positive and HER2-Low Cancers
FDA approves Enhertu for several types of HER2 positive cancers.
FDA approved Enhertu for several indications including HER2-positive metastatic breast cancer, HER2-low and HER2-ultralow breast cancer, HER…
The FDA has approved Enhertu for multiple cancers, including breast, lung, stomach, and other solid tumors that have a specific protein call…
H. pylori prevalence 34.3% in French Guiana; gastric adenocarcinoma found in 1.65%
One Third of Stomach Tests Show Hidden Bacteria Risk
A retrospective cohort study of 545 patients with H.
A new look at stomach biopsies shows one in three patients carry a hidden bacteria that can lead to serious disease.
Review of 35 cases highlights diagnostic challenges in gastric metastasis from invasive lobular breast cancer
Breast Cancer Spreads to Stomach: Why Testing Must Change
This case report and literature review synthesizes data from 35 recent cases (2019–2024) of gastric metastasis from breast cancer.
Doctors must re-test stomach issues in breast cancer patients because the cells often change their identity.
Case report details long-term survival in appendiceal signet-ring cell carcinoma with uterine involvement
A rare cancer found in the uterus and ovaries may be treated with surgery and chemo for over five years
This case report describes a 45-year-old woman with signet-ring cell carcinoma of the appendix involving the uterus and ovaries.
A rare cancer starting in the appendix showed up in the uterus and ovaries. Treatment with surgery and drugs helped a woman survive past fiv…
Case report describes sintilimab-associated toxic epidermal necrolysis in gastric carcinoma patient
Rare Skin Reaction Follows Successful Stomach Cancer Therapy
This case report details a patient with gastric carcinoma developing delayed-onset toxic epidermal necrolysis during neoadjuvant sintilimab …
A new case shows a common stomach cancer drug can cause dangerous skin reactions even after surgery.
Envafolimab plus lenvatinib and paclitaxel shows activity in advanced gastric cancer after first-line progression
New Drug Combo Gives Hope for Late-Stage Stomach Cancer
This phase II, single-center, open-label trial evaluated envafolimab combined with lenvatinib and albumin-bound paclitaxel in 30 patients wi…
Imagine a patient who has already tried every standard treatment available.
Serplulimab with FOLFOX showed disease control in AFP-producing gastric adenocarcinoma with liver metastases
Rare Stomach Cancer Shrinks After New Combo Treatment
This case report and literature review describes a 67-year-old man with AFP-producing gastric adenocarcinoma and liver metastases treated wi…
A rare stomach cancer that spread to the liver shrank dramatically when doctors combined standard chemotherapy with a newer immune-boosting …
Genomic and functional analyses address missing heritability in HDGC-like families lacking CDH1 and CTNNA1 variants
Why Some Stomach Cancer Families Were Missing a Genetic Answer All Along
This cohort study analyzed 19 HDGC-like probands and six additional families to investigate mechanisms of hereditary diffuse gastric cancer …
A new genetic study found missing causes of hereditary stomach cancer in nearly half of families who had previously tested negative.
FMT + Nivolumab Shows 20% ORR in 10 ICI-Refractory GI Cancer Patients
Could a gut bacteria transplant help when immunotherapy stops working for stomach cancer?
A phase I study in 10 patients with anti-PD-(L)1-refractory GI cancers found the combination of fecal microbiota transplantation (FMT) and n…
When stomach cancer resists standard immunotherapy, a gut bacteria transplant combined with treatment helped tumors shrink in two patients a…