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Home › Conditions › Hyperparathyroidism

Hyperparathyroidism

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Hyperparathyroidism

46 trials tracked for Hyperparathyroidism: 18 in phase 3 or 4 and 3 with published results. The most-cited published study has 302 citations.

46Trials tracked
18Phase 3 & 4
0Recruiting
3With published results
Phase distribution
Phase 4 9 Phase 3 9 Phase 2 8 Phase 1 4 Other / NA 16
  1. Phase 3 Head-to-Head Study of Etelcalcetide (AMG 416) and Cinacalcet Completed · 302 cited
  2. Phase 3 A Study to Evaluate the Safety of Paricalcitol Capsules in Pediatric Subjects Ages 10 to 16 With Stage 5 Chronic Kidney Disease Receiving Peritoneal Dialysis or Hemodialysis Completed · 19 cited
  3. Phase 4 Trial to Optimize Mineral Outcomes in Dialysis Patients Completed · 4 cited
  4. Phase 4 A Study of Zemplar® Injection and Hectorol® Injection on Intestinal Absorption of Calcium in Chronic Kidney Disease Completed
  5. Phase 4 Efficacy and Safety of 6 Months Treatment With Paricalcitol Injection or Oral in Patients With Secondary Hyperparathyroidism on Dialysis Completed
  6. Phase 4 20070360 Incident Dialysis Completed
Show 40 more trials
  1. Phase 4 Effectiveness and Safety of IV Zemplar in Patients on Hemodialysis and With Secondary Hyperparathyroidism Using iPTH/100 as Initial Dose Completed
  2. Phase 4 Evaluation of the Effectiveness of Paricalcitol Versus Cinacalcet With Low-Dose Vitamin D Completed
  3. Phase 4 A Study of Cinacalcet to Improve Achievement of National Kidney Foundation Kidney Disease Outcomes Quality Initiative (K/DOQI) Targets in Patients With End Stage Renal Disease (ESRD) Completed
  4. Phase 4 Paricalcitol Versus Calcitriol for Efficacy and Safety in Stage 3/4 Chronic Kidney Disease (CKD) With Secondary Hyperparathyroidism (SHPT) Completed
  5. Phase 4 ADVANCE: Study to Evaluate Cinacalcet Plus Low Dose Vitamin D on Vascular Calcification in Subjects With Chronic Kidney Disease Receiving Hemodialysis Completed
  6. Phase 3 Safety/Efficacy Study of CTAP101 in Chronic Kidney Disease Subjects With Secondary Hyperparathyroidism (SHPT) Completed
  7. Phase 3 Head-to-Head Study of Etelcalcetide and Cinacalcet in Asian Hemodialysis Patients With Secondary Hyperparathyroidism (SHPT) Completed
  8. Phase 3 E.V.O.L.V.E. Trial™: EValuation Of Cinacalcet Hydrochloride (HCl) Therapy to Lower CardioVascular Events Completed
  9. Phase 3 Effectiveness of Paricalcitol in Reducing Parathyroid Hormone (PTH) Levels in X-linked Hypophosphatemic Rickets Completed
  10. Phase 3 Sevelamer and Secondary Hyperparathyroidism in Chronic Kidney Disease Completed
  11. Phase 3 Comparison of Efficacy and Safety of Paricalcitol Injection With Maxacalcitol Injection in Adult Japanese Chronic Kidney Disease Subjects Receiving Hemodialysis With Secondary Hyperparathyroidism Completed
  12. Phase 3 Treatment of Autonomous Hyperparathyroidism in Post Renal Transplant Recipients Completed
  13. Phase 2 Safety, Tolerability and Efficacy of Etelcalcetide in Hemodialysis Patients With Secondary Hyperparathyroidism Completed
  14. Phase 2 Paricalcitol Compared to Maxacalcitol in Chronic Kidney Disease Patients With Secondary Hyperparathyroidism Completed
  15. Phase 2 Dose-response Study of Paricalcitol Injection in Chronic Kidney Disease Patients Receiving Hemodialysis Completed
  16. Phase 2 Bone Biopsy Study For Dialysis Patients With Secondary Hyperparathyroidism of End Stage Renal Disease Completed
  17. Phase 2 Long-term Safety Study of Paricalcitol Injection in Chronic Kidney Disease Patients With Hemodialysis (HD) Completed
  18. Phase 2 Study for Secondary Hyperparathyroidism in Chronic Renal Insufficiency Patients Completed
  19. Phase 2 Studies of Elevated Parathyroid Activity Completed
  20. Phase 2 Etelcalcetide to Treat Secondary Hyperparathyroidism in Hemodialysis Patients With Chronic Kidney Disease-Mineral and Bone Disorder Completed
  21. Phase 1 A Phase 1 Study to Evaluate PK, Safety and Tolerability of AMG 416 Completed
  22. Phase 1 One Week Parathyroid Hormone-related Protein (PTHrP) IV Dose Escalation Study Completed
  23. Phase 1 Study to Evaluate Cinacalcet in Children With Chronic Kidney Disease Completed
  24. Phase 1 7 Day Continuous Parathyroid Hormone IV Infusion Completed
  25. N/A Quality of Life in Greek Hemodialysis Patients Receiving Zemplar Intravenous Completed
  26. N/A Study to Assess Patient Management Practices and Quality of Life With Paricalcitol Capsules in the Treatment of Secondary Hyperparathyroidism in Stage 3-5 Chronic Kidney Disease Patients Not Yet on Dialysis Completed
  27. N/A Long-Term Therapy Outcomes When Treating Chronic Kidney Disease (CKD) Patients With Paricalcitol in German and Austrian Clinical Practice Completed
  28. N/A FGF-23 (Fibroblast Growth Factor 23) Regulation in Chronic Kidney Disease Completed
  29. N/A Follow-up Patients With End Stage Renal Disease Receiving Zemplar to Prevent and Treat Secondary Hyperparathyroidism Completed
  30. N/A Paricalcitol Oral Therapy in Predialysis CKD Patients. The Greek Experience Completed
  31. N/A Maintenance Vitamin D Therapy for Secondary Hyperparathyroidism (2HPT) Completed
  32. N/A Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Parathyroidectomy Completed
  33. N/A Vascular Risk After Kidney Transplantation Completed
  34. N/A Study of the Efficacy of Local Analgesia as an Adjunct to General Anesthesia in Thyroidectomy and Parathyroidectomy Completed
  35. N/A Efficacy and Safety of Ultrasonic Ablation to Treat Secondary Hyperparathyroidism in Chronic Kidney Disease Patients Completed
  36. N/A Study to Evaluate the Effect of Intravenous (IV) Paricalcitol (Zemplar) on Cardiac Morbidity in Patients With Chronic Kidney Disease (CKD) Stage 5 Over 2 Years Completed
  37. N/A Evaluation of Treatment With Zemplar Capsules in the Therapy of Secondary Hyperparathyroidism (SHPT) Completed
  38. N/A Observational Program of Zemplar in Patients With End Stage Chronic Kidney Disease and Parathyroid Disorder on Hemodialysis in the Russian Federation Completed
  39. N/A The Renin-Angiotensin-Aldosterone System and Parathyroid Hormone Control: The RAAS-PARC Study Completed
  40. N/A Suspected Deficient Activation of Vitamin D in Patients With Secondary Hyperparathyroidism Completed

Showing the 46 most-cited and recently-updated of 46 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Case report suggests hemorrhagic fever with renal syndrome may trigger secondary hyperparathyroidism
Diabetes & Endocrinology Sys. Review
Case report suggests hemorrhagic fever with renal syndrome may trigger secondary hyperparathyroidism Kidney Failure Causes Hormone Surge in Rare Virus Recovery
This case report describes a patient with hemorrhagic fever with renal syndrome in whom secondary hyperparathyroidism was suspected to be tr…
A rare virus causing sudden kidney failure may unexpectedly spike hormone levels during recovery, revealing a hidden complication doctors ra…
Frontiers May 9, 2026
NIRAF imaging associated with improved parathyroid identification during thyroidectomy in retrospective study
Diabetes & Endocrinology Cohort
NIRAF imaging associated with improved parathyroid identification during thyroidectomy in retrospective study Can a special light help surgeons spot tiny glands during thyroid surgery?
A retrospective cohort study of 349 patients undergoing total thyroidectomy found NIRAF-assisted identification was associated with more gla…
A special light helps surgeons spot more tiny calcium-controlling glands during thyroid surgery, leading to higher hormone levels right afte…
Frontiers Apr 8, 2026