Herbal medicines and phytoconstituents modulate vagus nerve activity and cholinergic neurotransmission in animal models
Herbal Medicines May Influence Vagus Nerve Activity in Animal Models
This systematic review of 75 preclinical studies evaluates how herbal medicines, phytoconstituents, and essential oils influence vagus nerve…
Early research in animal models suggests that various herbal medicines and essential oils may influence vagus nerve activity and reduce infl…
Quercetin immunity research surges, mapping review finds 12 thematic clusters
Mapping the growth of quercetin research for immune health
This systematic mapping review analyzed 10,619 unique publications on quercetin and immunity, finding that 6,440 (60.65%) appeared during 20…
A massive review of over 10,000 publications reveals how research into the compound quercetin is expanding to tackle inflammation and infect…
Aberrant IgG glycosylation correlates with cancer progression and serves as a novel aging-associated factor
New research links immune proteins to cancer and aging processes
This narrative review explores the role of Immunoglobulin G (IgG) in cancer progression and multi-organ aging processes. The authors synthes…
A new look at immune proteins called IgG reveals how they change as we age and play a role in how cancer progresses.
TET2 functions as a tumor suppressor in myeloid malignancies and immunomodulator in solid tumors
TET2 protein acts as a key regulator in several diseases
This systematic review examines the role of TET2 across various conditions including hematological malignancies, solid tumors, and inflammat…
A key protein called TET2 helps control cell behavior and may play a major role in treating cancer and inflammatory conditions.
Acidic microenvironments reprogram immune cells via pH sensors, driving tissue injury
Acidic environments in the body change how immune cells work
This systematic review synthesizes evidence that acidic microenvironments influence immune cell metabolism and effector functions through pr…
Your immune system uses special sensors to detect acid levels, which can trigger inflammation and tissue damage during infections or cancer.
Transcutaneous Vagus Nerve Stimulation utilizes distinct auricular and cervical pathways for non-invasive treatment applications
Two different ways to stimulate the vagus nerve for treatment
This narrative review examines the anatomical access points and methodologies for transcutaneous Vagus Nerve Stimulation (tVNS). It distingu…
New research highlights two distinct paths for non-invasive nerve stimulation to treat conditions like migraine and depression.
Narrative review discusses paradoxical inflammatory reactions in pediatric patients receiving biologic therapy
Biologic therapy may cause paradoxical inflammation in children
This narrative review examines paradoxical inflammatory reactions in pediatric patients receiving biologic therapy. The authors note that a …
A review notes that biologic therapy can trigger paradoxical inflammatory reactions in pediatric patients, highlighting a need for careful m…
Molecular review explores Siglec signaling pathways in cancer and inflammatory disorders
Siglec proteins help immune system balance fighting disease and avoiding self-harm
This molecular review examines the role of Siglec signaling pathways in human biology. The authors discuss potential therapeutic opportuniti…
Siglec proteins act as brakes on immune cells, and targeting them could help treat cancer and autoimmune disorders.
Narrative review outlines sialidase biology roadmap for genetic syndromes and inflammatory disorders
Sialidase Clues Solve Mystery Diseases Doctors Couldn't Explain
This narrative review examines sialidase biology across genetic syndromes, infectious pathogens, inflammatory disorders, autoimmune disorder…
• Sialidase imbalance links rare genetic disorders to common diseases like cancer • Patients with mysterious symptoms getting wrong treatmen…
Narrative review advocates multi-omics models to clarify exercise associations
Exercise links to health benefits, but direct causation remains associative
This narrative review discusses the complex relationship between exercise and health outcomes.
A narrative review suggests exercise connects to health outcomes, though direct causation remains associative and knowledge gaps persist.
Integrative review of Tedania sponge compounds for cancer and infections
Sponge Compounds May Fight Cancer and Infections, Study Suggests
This integrative review synthesizes evidence on 135 compounds from Tedania marine sponges for cancer, inflammatory diseases, and microbial i…
Marine sponges are a rich source of natural compounds that could one day lead to new treatments for cancer and infections, but more research…
Retrospective FAERS analysis reveals sex-specific adverse event patterns for apremilast, crisaborole, and roflumilast in chronic inflammatory diseases
Why Side Effects Hit Men and Women Differently
This retrospective pharmacovigilance study analyzed 127,516 apremilast reports, 7,562 crisaborole reports, and 2,142 roflumilast reports wit…
A massive new analysis reveals that common anti-inflammatory drugs cause different side effects in men and women, meaning biology is more co…
Questions about inflammatory diseases
Does targeting ISG15 help with skin inflammatory diseases?
Targeting the ISG15 pathway shows potential for treating skin inflammatory diseases because ISG15 can act as a cytokine that worsens inflammation, but current research is mostly theoretical.
Full answer →Can marine sponge compounds treat infections and inflammatory diseases?
Marine sponge compounds show promise for treating infections and inflammatory diseases, with specific examples like manzamines for malaria and diketopiperazines for sepsis.
Full answer →All inflammatory diseases Articles
- Herbal medicines and phytoconstituents modulate vagus nerve activity and cholinergic neurotransmission in animal models
- Quercetin immunity research surges, mapping review finds 12 thematic clusters
- Aberrant IgG glycosylation correlates with cancer progression and serves as a novel aging-associated factor
- TET2 functions as a tumor suppressor in myeloid malignancies and immunomodulator in solid tumors
- Acidic microenvironments reprogram immune cells via pH sensors, driving tissue injury
- Transcutaneous Vagus Nerve Stimulation utilizes distinct auricular and cervical pathways for non-invasive treatment applications
- Narrative review discusses paradoxical inflammatory reactions in pediatric patients receiving biologic therapy
- Molecular review explores Siglec signaling pathways in cancer and inflammatory disorders
- Narrative review outlines sialidase biology roadmap for genetic syndromes and inflammatory disorders
- Narrative review advocates multi-omics models to clarify exercise associations
- Integrative review of Tedania sponge compounds for cancer and infections
- Retrospective FAERS analysis reveals sex-specific adverse event patterns for apremilast, crisaborole, and roflumilast in chronic inflammatory diseases
- Review of ISG15 pathway targeting for inflammatory and cardiovascular diseases