Research across Psoriasis
Related studies from across the Psoriasis family.
Autoimmune comorbidities recur with MS, but evidence cannot define a prodrome or distinct subgroups
Common autoimmune conditions often occur alongside multiple sclerosis
This scoping review synthesizes evidence on immune-mediated comorbidities in multiple sclerosis. Autoimmune thyroid disease, type 1 diabetes…
People with multiple sclerosis often have other autoimmune conditions like thyroid disease or psoriasis, but the link to disease progression…
Icotrokinra increases likelihood of Investigator's Global Assessment 0 or 1 by risk ratio 7.27
Icotrokinra Shows Promise for Moderate to Severe Plaque Psoriasis
This meta-analysis of icotrokinra for moderate-to-severe plaque psoriasis in adolescents and adults found a risk ratio of 7.27 for Investiga…
A new treatment called icotrokinra shows significant skin clearance and improved scores for adults and teens with moderate to severe plaque …
Telitacicept Shows Satisfactory Response in Complex Overlap Syndrome Case
Telitacicept Shows Potential in Rare Overlap Syndrome Case
This is a single case report describing a patient with systemic lupus erythematosus, immune-mediated necrotizing myopathy, Sjögren's syndrom…
A single case report describes a patient with four autoimmune conditions who responded well to a regimen containing telitacicept.
Vigorous activity and regular exercise are associated with lower psoriasis prevalence in patients with psoriasis
Regular Exercise May Help Manage Psoriasis and Joint Pain
This umbrella review synthesizes evidence on exercise, physical activity, and fitness for patients with psoriasis and psoriatic arthritis. T…
Regular physical activity and vigorous exercise may be linked to lower psoriasis prevalence and improved symptoms for those with psoriatic a…
Comparative Efficacy and Safety of Ustekinumab Biosimilars versus Reference Products in Plaque Psoriasis
Ustekinumab biosimilars show similar results to the original drug
Meta-analysis confirms that ustekinumab biosimilars demonstrate comparable efficacy and safety profiles to the reference product for moderat…
New data shows that biosimilar versions of the drug ustekinumab work just as well as the original for people with moderate to severe plaque …
Inflammatory memory mechanisms may drive chronic relapse and offer pathways for disease modification in rosacea
New framework explores why rosacea and psoriasis keep returning
This hypothesis-generating critical review explores inflammatory memory, including epigenetic memory and trained immunity, as a framework fo…
Scientists are looking into how the body remembers inflammation, which could help explain why skin conditions like rosacea often flare up re…
Keratinocytes drive psoriasis inflammation through bidirectional epithelial-immune crosstalk
Skin cells play a key role in driving psoriasis inflammation
This narrative review synthesizes evidence that keratinocytes are active participants in a bidirectional epithelial-immune network driving p…
New research shows that skin cells are not just passive victims of psoriasis but active participants in driving the cycle of inflammation.
IRF4 acts as a context-encoded mediator in immune compartments and skin repair processes
Understanding the Role of IRF4 in Treating Skin Inflammation Conditions
This narrative review examines the role of Interferon regulatory factor 4 (IRF4) in immune compartments and skin conditions. The review iden…
Scientists are looking at how the IRF4 protein affects skin diseases like psoriasis and eczema to find better ways to manage symptoms.
Neural interactions and cellular components in psoriasis may offer new therapeutic targets for treatment
New Research Identifies Nervous System Links in Psoriasis Treatment
This systematic review examines the interactions between multiple cellular components and the nervous system in psoriasis. The review aims t…
New research explores how the nervous system interacts with skin cells in psoriasis to help identify new ways to treat the condition.
Guselkumab achieves 88.8% IGA 0/1 at week 16 in Chinese patients with plaque psoriasis
Trial shows guselkumab helps Chinese patients with plaque psoriasis
This Phase 4 randomized controlled trial of 327 Chinese patients with moderate-to-severe plaque psoriasis found guselkumab significantly sup…
A new trial shows that guselkumab significantly improves skin clarity for Chinese patients living with moderate to severe plaque psoriasis.
Vunakizumab may induce severe ulcerative colitis and hepatic enzyme elevation in patients with psoriatic arthritis
Vunakizumab Linked to Severe Ulcerative Colitis in Single Case
This case report and literature review describes a single case of severe ulcerative colitis and hepatic enzyme elevation following vunakizum…
A single case report shows a patient developed severe ulcerative colitis and high liver enzymes after receiving vunakizumab injections.
BAT2306 shows comparable efficacy and safety to secukinumab in moderate-to-severe plaque psoriasis
Trial shows BAT2306 performs similarly to secukinumab for plaque psoriasis
This Phase 3 randomized controlled trial evaluated 502 adults with moderate-to-severe plaque-type psoriasis. The study found that BAT2306 de…
A new clinical trial shows that the medication BAT2306 offers similar results and safety for plaque psoriasis compared to the established dr…