Mode
Home
Research
Clinical Trials Drug Pipeline Weekly Digests
Reference
Conditions Medications
Community
Questions
Text Size
Log in / Sign up
Home › Conditions › Loneliness

Loneliness

Part of Social Isolation

4 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Loneliness

16 trials tracked for Loneliness.

16Trials tracked
0Phase 3 & 4
0Recruiting
0With published results
  1. N/A The Loneliness Epidemic Tailoring Interventions to Reduce Loneliness and Pain Completed
  2. N/A The Association Between Loneliness and Substance Use Completed
  3. N/A Engage Psychotherapy to Promote Connectedness in Caregivers Completed
  4. N/A Reducing Loneliness of Older Adults in Long Term Care Facilities Through Collaborative Augmented Realities Completed
  5. N/A The BE WITH Project: A Partially Nested Randomized Control Trial (PN-RCT) Completed
  6. N/A Engage Coaching for Latinos Completed
Show 10 more trials
  1. N/A Twitter Based Social Support for Hispanic and Black Dementia Caregivers Completed
  2. N/A Ecological Momentary Assessment and Text Message Intervention for Stress Management Completed
  3. N/A Rural Dementia Caregiver Project Completed
  4. N/A Connect for Caregivers Completed
  5. N/A Loving Kindness Meditation Among Adults 50 Years and Older Completed
  6. N/A Technology and Family Thriving Study Completed
  7. N/A Mindfulness to Reduce Loneliness in Older Caregivers Completed
  8. N/A Stay Connected: Testing an Intervention to Combat Coronavirus-related Social Isolation Among Older Adults Completed
  9. N/A The Emotional, Physical and Cognitive Benefits of Purposeful Green Space Activities on Seniors Completed
  10. N/A The Helping Older People Engage Project: Improving Social Well-Being in Later Life Completed

Showing the 16 most-cited and recently-updated of 16 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Nurse-led pathways for loneliness and social isolation in older adults show heterogeneous clinical outcomes
Gastroenterology Sys. Review
Nurse-led pathways for loneliness and social isolation in older adults show heterogeneous clinical outcomes Nurse led pathways may help older adults with loneliness
This narrative review examines nurse-led pathways to address loneliness and social isolation in older adults. The authors synthesize evidenc…
New research explores how nurses can lead specific pathways to help older adults cope with loneliness and social isolation.
Frontiers Sep 23, 2026
Social and emotional skills training shows non-significant reductions in loneliness among children and adolescents
Pediatrics Meta-analysis
Social and emotional skills training shows non-significant reductions in loneliness among children and adolescents Social and Emotional Training Shows Promise for Youth Loneliness
This meta-analysis of 18 studies evaluated interventions targeting loneliness, including social and emotional skills training, in youth aged…
New research looks at how social and emotional skills training can help reduce feelings of loneliness in children and teenagers.
Jun 15, 2026
Systematic review and meta-analysis of digital technology interventions for cognitive function and mood in older adults
Psychiatry Meta-analysis
Systematic review and meta-analysis of digital technology interventions for cognitive function and mood in older adults Digital tools may boost brain health in older adults
This systematic review and meta-analysis evaluated digital technology interventions in older adults with cognitive impairment, depression, a…
Using digital technology like apps or online programs may improve thinking skills and mood in older adults, a new analysis suggests.
May 1, 2026
Observational report examines loneliness prevalence among U.S. adults
Psychiatry
Observational report examines loneliness prevalence among U.S. adults How many U.S. adults feel lonely? A new report looks at the numbers
An observational report describes the prevalence of loneliness in U.S.
A new report puts a spotlight on loneliness as a widespread public health concern affecting many U.S. adults.
CDC Apr 3, 2026

Questions about Loneliness

Are there different outcomes for nurse-led programs for loneliness?

Nurse-led programs for loneliness show varied results, with some studies showing significant improvements while others show only modest or non-significant changes depending on the specific focus of the program.

Full answer →
Can digital technology help with mood and loneliness in older adults?

Digital technology interventions can improve mood and cognitive function in older adults, but their specific effectiveness in reducing loneliness is less clear.

Full answer →
Does social skills training help children and teens with loneliness?

Social and emotional skills training shows some promise in reducing loneliness in children and adolescents, though results in clinical studies have been inconsistent.

Full answer →