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Allergy & Immunology
Meta-analysis
Meta-analysis identifies DNA methylation markers linked to asthma exacerbations in diverse pediatric populations
Blood Markers May Predict Severe Asthma Attacks in Kids
This meta-analysis synthesizes data from African American and Latino pediatric populations and ethnically diverse participants to evaluate D…
New research spots chemical changes in blood that signal when asthma might get dangerous.
medRxiv
Apr 19, 2026
Allergy & Immunology
RCT
Combined digital and paper audit feedback did not improve asthma prescribing versus digital-only in primary care
Paper Letters Add Nothing to Digital Asthma Care Plans
This cluster randomized controlled trial in 270 primary care practices in West Yorkshire compared combined digital and paper audit and feedb…
Sending printed reports to doctors does not improve asthma care more than sending emails.
Apr 19, 2026
Genetics & Precision Medicine
Cohort
Polygenic risk scores improve identification of rare variant carriers in idiopathic pulmonary fibrosis patients
Can a genetic test help spot hidden lung disease risks in pulmonary fibrosis patients?
This observational cohort study of 888 IPF patients from the PFF-PR and 472 from the UK PROFILE cohort found that polygenic risk scores (PRS…
A genetic test helps doctors spot hidden disease risks in lung patients by finding rare gene variants that standard history alone might miss…
medRxiv
Apr 19, 2026
Diabetes & Endocrinology
Review of UK Biobank data identifies plasma protein mediators in cardiometabolic disease progression
New Blood Test Clues Could Predict Diabetes Complications Years Earlier
This observational review analyzes UK Biobank data from 53,030 participants to evaluate plasma proteins as mediators in secondary disease de…
A new blood test spots specific proteins that warn of heart, kidney, and brain problems years before they happen in people with diabetes or …
medRxiv
Apr 19, 2026
Genetics & Precision Medicine
Observational biobank study compares phenomic and social determinants for disease risk prediction
Your Genes Aren’t Your Destiny: How Your Neighborhood Changes Your Risk
This research article from UK Biobank and other cohorts evaluates phenome-derived polygenic scores and social determinants for predicting as…
Your neighborhood and lifestyle can reshape your genetic risk for diseases like asthma and heart disease, offering a clearer health picture …
medRxiv
Apr 19, 2026
Pulmonology & Critical Care
Meta-analysis
Systematic review and meta-analysis of pulmonary telerehabilitation versus center-based care in COPD
Remote Breathing Rehab Works Just as Well as In-Clinic Visits for COPD
This systematic review and meta-analysis synthesized evidence on pulmonary telerehabilitation (Tele-PR) versus center-based rehabilitation (…
Remote breathing rehab matches in-clinic visits for COPD patients, offering a flexible option for those who struggle to travel for care.
Apr 18, 2026
Pulmonology & Critical Care
Meta-analysis
Systematic review finds high relapse rates in pulmonary sarcoidosis across diverse study designs
Pulmonary Sarcoidosis Relapse: 40% of Patients Face Recurrence, New Study Reveals
This systematic review and meta-analysis evaluated the prevalence of relapse in patients with pulmonary sarcoidosis.
About 4 in 10 people with pulmonary sarcoidosis see their disease return after treatment, with higher risks for Black patients and those wit…
medRxiv
Apr 18, 2026
Pulmonology & Critical Care
RCT
Multicomponent breathing and exercise program improves breathlessness mastery in moderate to severe COPD
New Breathing Program Helps COPD Patients Regain Control Over Daily Life
In this randomized controlled trial of 113 patients with moderate to severe COPD and disabling breathlessness, an 8-week multicomponent inte…
An 8-week coaching program helps severe COPD patients control breathlessness and reduce daily discomfort without relying only on medication.
Apr 18, 2026
Infectious Disease
Sys. Review
Narrative review examines lung microbiome and mucosal IgA in chronic inflammatory lung diseases
Your Lungs Have Their Own Microbiome — and It Affects Your Immune Defenses
This narrative review explores the interplay between the lung microbiome and mucosal immunoglobulin A system in chronic inflammatory lung di…
The lung's microbiome and immune protein IgA work together to protect health, and their breakdown drives chronic lung diseases like asthma a…
Frontiers
Apr 18, 2026
Infectious Disease
RCT
Adjuvanted RSV vaccine shows efficacy against RSV disease in older adults with comorbidities
One RSV Shot Protects High-Risk Older Adults for Three Full Seasons
This post-hoc analysis of a phase 3 trial evaluated an adjuvanted RSVPreF3 dose in medically stable adults aged 60 and older with underlying…
One RSV shot cuts illness risk by 63% to 75% for older adults with COPD, asthma, diabetes, or obesity over three full seasons.
medRxiv
Apr 18, 2026
Rheumatology
Cohort
Relaxation training and early benzodiazepines linked to respiratory recovery in adults with COPD, pneumonia, asthma, bronchiectasis, or interstitial lung disease
Could early sedatives be slowing down lung recovery for adults with breathing problems?
This retrospective observational study examined 389 consecutive adults (≥ 18 years) admitted with chronic obstructive pulmonary disease, pne…
Early sedatives given to adults with breathing problems may slow lung recovery, making it harder for patients to improve before leaving the …
Frontiers
Apr 18, 2026
Pulmonology & Critical Care
Feasibility study abstract evaluates home spirometry and FeNO for asthma diagnosis in adults
Home Testing Tools Show Potential for Asthma Diagnosis in Adults
This abstract reports a feasibility study evaluating home spirometry and fractional exhaled nitric oxide (FeNO) monitoring for asthma diagno…
Home breathing and airway tests showed high accuracy for diagnosing asthma in adults, potentially cutting the need for invasive clinic chall…
medRxiv
Apr 18, 2026