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Home › Conditions › Medulloblastoma

Medulloblastoma

Part of Glioma

3 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Medulloblastoma

18 trials tracked for Medulloblastoma: 2 in phase 3 or 4 and 1 with published results. The most-cited published study has 198 citations.

18Trials tracked
2Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 3 2 Phase 2 11 Phase 1 2 Other / NA 3
  1. Phase 3 Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma Completed · 198 cited
  2. Phase 3 Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma Completed
  3. Phase 2 A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MB Completed
  4. Phase 2 Vaccine Immunotherapy for Recurrent Medulloblastoma and Primitive Neuroectodermal Tumor Completed
  5. Phase 2 A Phase II Study of Oral LDE225 in Patients With Hedge-Hog (Hh)-Pathway Activated Relapsed Medulloblastoma (MB) Completed
  6. Phase 2 Combination of Irinotecan and Temozolomide in Children With Brain Tumors. Completed
Show 12 more trials
  1. Phase 2 Dosimetry-Guided, Peptide Receptor Radiotherapy (PRRT) With 90Y-DOTA- tyr3-Octreotide (90Y-DOTATOC) Completed
  2. Phase 2 Study of Nifurtimox to Treat Refractory or Relapsed Neuroblastoma or Medulloblastoma Completed
  3. Phase 2 A Study of Pemetrexed in Children With Recurrent Cancer Completed
  4. Phase 2 Impact of Ga-68 DOTATOC PET-CT Imaging in Management of Neuroendocrine Tumors Completed
  5. Phase 2 Safety of 68Ga-DOTA-tyr3-Octreotide PET in Diagnosis of Solid Tumors Completed
  6. Phase 2 A Study of Pomalidomide Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors Completed
  7. Phase 2 Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed, Non-metastatic Desmoplastic Medulloblastoma Completed
  8. Phase 1 TPI 287 in Patients With Refractory or Recurrent Neuroblastoma or Medulloblastoma Completed
  9. Phase 1 Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children Completed
  10. N/A Molecular-Guided Therapy for Relapsed and Refractory Childhood Cancer Completed
  11. N/A Molecular-Guided Therapy for Childhood Cancer Completed
  12. N/A Proton Beam Radiotherapy for Medulloblastoma and Pineoblastoma Completed

Showing the 18 most-cited and recently-updated of 18 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Reduced-dose craniospinal radiation and smaller volume boost for medulloblastoma patients
Pediatrics Phase III
Reduced-dose craniospinal radiation and smaller volume boost for medulloblastoma patients Trial Shows Reduced Radiation May Help Children With Medulloblastoma
This randomized phase 3 trial evaluated reduced-dose craniospinal radiation (18.00 Gy) and a smaller volume boost in children aged 3 to 7 wi…
A large clinical trial looked at whether reducing radiation doses for children with medulloblastoma can maintain safety and effectiveness.
CT.gov Jun 10, 2026
Narrative Review Explores Immune Checkpoint Inhibition in Pediatric Medulloblastoma
Hematology Sys. Review
Narrative Review Explores Immune Checkpoint Inhibition in Pediatric Medulloblastoma New immune targets offer hope for children with recurrent brain tumors
This narrative review discusses the potential of immune checkpoint inhibition via direct antibody targeting in pediatric medulloblastoma. Th…
A new generation of immune drugs is being tested to help children whose brain tumors have returned after standard treatment
Frontiers May 9, 2026
Narrative review explores CSF1R inhibitor potential in pediatric medulloblastoma precision immunotherapy
Diabetes & Endocrinology Sys. Review
Narrative review explores CSF1R inhibitor potential in pediatric medulloblastoma precision immunotherapy The Hidden Reason Children's Brain Tumors Respond So Differently to Treatment
This narrative review examines the role of CSF1R inhibitors as precision immunotherapy for pediatric medulloblastoma subtypes.
Each subtype of children's brain tumors has a unique immune fingerprint, meaning matching treatment to that specific environment could drama…
Frontiers Apr 18, 2026