Cisplatin-based chemotherapy associated with superior survival over carboplatin in advanced bladder cancer
Cisplatin shows better survival for patients with bladder cancer
This meta-analysis of 2543 patients found that cisplatin-based regimens are associated with significantly better overall survival and cancer…
New data reveals that cisplatin-based chemotherapy leads to longer survival than carboplatin for many people with advanced bladder cancer.
Reduced-dose craniospinal radiation and smaller volume boost for medulloblastoma patients
Trial Shows Reduced Radiation May Help Children With Medulloblastoma
This randomized phase 3 trial evaluated reduced-dose craniospinal radiation (18.00 Gy) and a smaller volume boost in children aged 3 to 7 wi…
A large clinical trial looked at whether reducing radiation doses for children with medulloblastoma can maintain safety and effectiveness.
Tislelizumab plus chemotherapy improves survival in extensive-stage small cell lung cancer
Immunotherapy combo extends survival in small cell lung cancer
This phase 3 RCT evaluated tislelizumab plus chemotherapy versus placebo plus chemotherapy in previously untreated extensive-stage small cel…
Adding tislelizumab to chemo helped people with extensive-stage small cell lung cancer live 2 months longer, a phase 3 trial shows.
Chemo-immunotherapy yields 12-month disease-free status in rare triple-negative neuroendocrine breast cancer
A single patient remains disease-free after a new chemo-immunotherapy approach for rare breast cancer
This case report describes a 71-year-old woman with triple-negative neuroendocrine breast cancer treated with paclitaxel, cisplatin, and pem…
A 71-year-old woman with rare breast cancer stayed disease-free for a year using a combination of chemotherapy and immunotherapy that doctor…
20-fraction hypofractionated radiotherapy passes noninferiority for tumor control and late toxicity in locally advanced head and neck cancer
Shorter radiation schedule works as well for head and neck cancer
This randomized, open-label, Phase 3 noninferiority trial enrolled 792 patients with locally advanced head and neck squamous cell carcinoma …
A shorter radiation plan for head and neck cancer showed the same effectiveness as a longer schedule while reducing late side effects.
Irinotecan plus cisplatin shows no RFS benefit over etoposide plus cisplatin in resected lung HGNEC
Five-year follow-up shows irinotecan plus cisplatin matches etoposide plus cisplatin for lung cancer survival
This randomized, open-label, phase III study compared irinotecan plus cisplatin to etoposide plus cisplatin in 221 patients with resected hi…
A five-year look at lung cancer patients found that irinotecan plus cisplatin worked just as well as etoposide plus cisplatin for keeping th…
Ibrutinib plus chemo without ASCT shows survival benefit in mantle cell lymphoma
Adding stem cell transplant to ibrutinib treatment offered no extra benefit for lymphoma patients
In younger patients with mantle cell lymphoma, adding ASCT to an ibrutinib regimen did not improve outcomes but increased toxicity. Ibrutini…
Adding stem cell transplant to ibrutinib did not improve survival for younger lymphoma patients but increased side effects.
FDA approves OPDIVO QVANTIG for multiple advanced cancer indications including renal cell carcinoma and melanoma
FDA approves subcutaneous nivolumab combination for multiple advanced cancers
This FDA approval document grants authorization for OPDIVO QVANTIG, a subcutaneous combination of nivolumab and hyaluronidase, for specified…
The FDA has approved a new subcutaneous form of nivolumab for several advanced cancers, offering a more convenient treatment option for elig…
Meta-analysis shows neoadjuvant chemoradiation improves resection and survival outcomes for esophageal squamous cell carcinoma patients compared to chemotherapy alone
Adding radiation before surgery helps some esophageal cancer patients get better surgery results and live longer
This meta-analysis of 2,174 patients reveals that adding radiation to chemotherapy significantly boosts resection rates and survival for squ…
A large review found that adding radiation to chemotherapy before surgery helped remove more tumors in certain cancer types. This approach a…
Meta-analysis of pucotenlimab shows improved outcomes across multiple solid tumors
New analysis shows pucotenlimab improves outcomes for several solid tumor types
This meta-analysis evaluated pucotenlimab (HX008) in patients with gastric, gastroesophageal junction, triple-negative breast cancer, melano…
A new analysis of pucotenlimab shows significantly improved outcomes versus control for patients with gastric cancer, triple-negative breast…
Pre-treatment body composition and acute kidney disease risk in head and neck cancer patients treated with cisplatin
Body composition may link to kidney issues in cancer patients
This prospective, monocentric, observational study of 110 patients with locally advanced head and neck cancer found that acute kidney diseas…
Low muscle mass and low lymphocyte counts may be linked to kidney disease risk during head and neck cancer treatment.
Neoadjuvant Chemoimmunotherapy Alters Tumor Microenvironment in Esophageal Cancer
Combination therapy may help overcome resistance in esophageal cancer
This Phase 3 RCT in 55 patients with locally advanced esophageal squamous cell carcinoma compared neoadjuvant chemotherapy alone versus comb…
A small trial suggests combination therapy might help overcome resistance in esophageal cancer by targeting specific immune cells.
All cisplatin Articles
- Cisplatin-based chemotherapy associated with superior survival over carboplatin in advanced bladder cancer
- Reduced-dose craniospinal radiation and smaller volume boost for medulloblastoma patients
- Tislelizumab plus chemotherapy improves survival in extensive-stage small cell lung cancer
- Chemo-immunotherapy yields 12-month disease-free status in rare triple-negative neuroendocrine breast cancer
- 20-fraction hypofractionated radiotherapy passes noninferiority for tumor control and late toxicity in locally advanced head and neck cancer
- Irinotecan plus cisplatin shows no RFS benefit over etoposide plus cisplatin in resected lung HGNEC
- Ibrutinib plus chemo without ASCT shows survival benefit in mantle cell lymphoma
- FDA approves OPDIVO QVANTIG for multiple advanced cancer indications including renal cell carcinoma and melanoma
- Meta-analysis shows neoadjuvant chemoradiation improves resection and survival outcomes for esophageal squamous cell carcinoma patients compared to chemotherapy alone
- Meta-analysis of pucotenlimab shows improved outcomes across multiple solid tumors
- Pre-treatment body composition and acute kidney disease risk in head and neck cancer patients treated with cisplatin
- Neoadjuvant Chemoimmunotherapy Alters Tumor Microenvironment in Esophageal Cancer
- Case report details long-term survival in appendiceal signet-ring cell carcinoma with uterine involvement
- Pembrolizumab plus chemotherapy versus placebo plus chemotherapy in Chinese adults with advanced biliary tract carcinoma
- Early study of CDP1 plus chemotherapy showed promising activity and manageable safety in advanced penile cancer
- Durvalumab plus chemotherapy improves event-free and overall survival in muscle-invasive bladder cancer compared to chemotherapy alone
- Phase 3 trial compares IMPT versus IMRT plus cisplatin in locally advanced oropharyngeal squamous cell carcinoma
- Penpulimab plus chemotherapy significantly improved progression-free survival in recurrent or metastatic nasopharyngeal carcinoma
- Exploratory RCT finds in situ vaccine plus PD-1 with immunoradiotherapy shows response in advanced hepatic malignancies
- Phase II trial finds adding gemcitabine to cisplatin-radiotherapy does not improve 2-year disease-free survival in muscle-invasive bladder cancer
- Phase I study finds amrubicin-cisplatin with radiotherapy feasible in limited-stage SCLC
- Phase 3 trial of pembrolizumab plus chemo for advanced biliary tract carcinoma posts results
- Platinum-based intraperitoneal chemotherapy improves disease-free survival after curative CRC resection
- Induction Nivolumab Before CRT Misses Feasibility Threshold in High-Risk HPV+ OPC
- Triapine Added to Cisplatin and Radiation for Cervical/Vaginal Cancer: Phase III Results