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Home › Conditions › Neurofibromatosis Type 1

Neurofibromatosis Type 1

Part of Peripheral neuropathy

4 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Neurofibromatosis Type 1

10 trials tracked for Neurofibromatosis Type 1: 1 in phase 3 or 4.

10Trials tracked
1Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 3 1 Phase 2 8 Other / NA 1
  1. Phase 3 Acceptance and Commitment Training for Adolescents and Young Adults With Neurofibromatosis Type 1, Plexiform Neurofibromas, and Chronic Pain Completed
  2. Phase 2 A Randomized Placebo-Controlled Study of Lovastatin in Children With Neurofibromatosis Type 1 Completed
  3. Phase 2 A Phase II Study of the mTOR Inhibitor Sirolimus in Neurofibromatosis Type 1 Related Plexiform Neurofibromas Completed
  4. Phase 2 Low-Dose or High-Dose Lenalidomide in Treating Younger Patients With Recurrent, Refractory, or Progressive Pilocytic Astrocytoma or Optic Pathway Glioma Completed
  5. Phase 2 Combination Chemotherapy in Treating Patients With Neurofibromatosis and Progressive Plexiform Neurofibromas Completed
  6. Phase 2 Bevacizumab in Treating Patients With Recurrent or Progressive Meningiomas Completed
Show 4 more trials
  1. Phase 2 Selumetinib in Treating Patients With Neurofibromatosis Type 1 and Cutaneous Neurofibroma Completed
  2. Phase 2 Phase II Study of Binimetinib in Children and Adults With NF1 Plexiform Neurofibromas Completed
  3. Phase 2 Combination Chemotherapy in Treating Patients With Stage III or Stage IV Malignant Peripheral Nerve Sheath Tumors Completed
  4. N/A Neurobiology and Treatment of Reading Disability in NF-1 Completed

Showing the 10 most-cited and recently-updated of 10 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Hepatic MPNST without NF1: normal tumor markers, no recurrence 2 years after resection
Oncology Sys. Review
Hepatic MPNST without NF1: normal tumor markers, no recurrence 2 years after resection Case Report Shows Surgery for Rare Liver Tumor Success
A case report and literature review describes a 56-year-old woman with hepatic malignant peripheral nerve sheath tumor (MPNST) without neuro…
A rare liver tumor known as MPNST was successfully treated with surgery, showing no signs of return after two years.
Frontiers Jun 12, 2026
Case report review of clindamycin use in a 62-year-old male with Neurofibromatosis type 1 and hematoma
Cardiology Sys. Review
Case report review of clindamycin use in a 62-year-old male with Neurofibromatosis type 1 and hematoma A Rare Bleeding Complication Every NF1 Patient Should Know About
This case report review describes the management of a 62-year-old male with Neurofibromatosis type 1 who presented with a hematoma. The pati…
A sudden pain or unexplained lump in someone with NF1 could signal a life-threatening bleed that needs emergency care right away.
Frontiers May 14, 2026
Mobile App with Contingency Management Improves Pain Outcomes in Adults with NF1
Anesthesiology & Pain Medicine RCT
Mobile App with Contingency Management Improves Pain Outcomes in Adults with NF1 Can a phone app help adults with NF1 manage their chronic pain?
A randomized trial in 108 adults with Neurofibromatosis Type 1 and chronic pain found that the iCanCope mobile app plus contingency manageme…
Adults with NF1 who used a phone app with rewards reported less pain interference and greater confidence in managing their chronic pain comp…
Apr 2, 2026
Case report describes multimodal treatment and single-cell sequencing in NF1 patient with Malignant Triton Tumor
Oncology
Case report describes multimodal treatment and single-cell sequencing in NF1 patient with Malignant Triton Tumor What happens when a rare cancer returns? One young woman's story offers a clue
A case report describes a 23-year-old woman with neurofibromatosis type 1 and Malignant Triton Tumor.
A 23-year-old woman with a rare chest tumor found disease stabilization after surgery failed, using a mix of chemotherapy, targeted therapy,…
Frontiers Apr 1, 2026