Genomic instability markers show associations with malignant transformation in oral leukoplakias and proliferative verrucous leukaplakias
Genomic markers show links to cancer in oral leukoplakia
This systematic review of 34 observational studies analyzed genomic instability markers in 3,237 patients with oral leukakias and proliferat…
New research identifies specific DNA markers that may help predict when oral leukoplakia turns into cancer.
Meta-analysis of oxidative stress markers in oral leukoplakia versus healthy controls
High Oxidative Stress Found in Oral White Patches
This systematic review and meta-analysis pooled data from 12 studies comparing patients with oral leukoplakia to healthy controls.
White patches in the mouth show higher oxidative stress than healthy tissue, helping doctors spot dangerous changes before they become cance…
Research across Head and Neck Cancer
Related studies from across the Head and Neck Cancer family.
YAP and TAZ Overexpression Predicts Worse Survival in Oral Squamous Cell Carcinoma
Hippo Pathway Markers Linked to Oral Cancer Survival Rates
This meta-analysis of 17 studies examined the prognostic value of Hippo pathway effectors YAP and TAZ in oral squamous cell carcinoma. Poole…
New data suggests that specific proteins in the Hippo pathway may help predict survival outcomes for patients with oral squamous cell carcin…
Oral HPV reshapes mucosal microbial composition in a sex and population dependent manner
Oral and genital health linked to specific bacteria and HPV
This mini-review synthesizes evidence regarding the interaction between HPV infection and mucosal microbiota in oral, anorectal, and penile …
New research shows how specific bacteria and the HPV virus interact in the mouth and genital areas to influence cancer risk.
SMMI framework provides a conceptual model for risk stratification in high-risk oral potentially malignant disorders
New Framework Helps Identify Risk of Oral Cancer Development
This evidence-ranked conceptual review proposes the spatial-microbial-metabolic-immune (SMMI) framework to study malignant transformation ri…
A new conceptual framework looks at how microbes and the immune system might help doctors better identify high risk for oral cancer developm…
Distinct microbial taxa and functional pathways are associated with oral squamous cell carcinoma
Specific Bacteria Linked to Oral Squamous Cell Carcinoma
This meta-analysis identifies specific microbial taxa and functional pathways associated with oral squamous cell carcinoma. The findings hig…
Researchers identified specific types of bacteria and genetic pathways that are more common in people with oral squamous cell carcinoma.
Submental Artery Island Flap Shows 16% Pooled Locoregional Recurrence in Oral Cavity Reconstruction
Submental artery island flap is a safe option for oral cancer
This meta-analysis pooled data on the submental artery island flap (SAIF) for oral cavity defects after oral squamous cell carcinoma resecti…
A specific surgical technique called the submental artery island flap shows a low recurrence rate for patients with oral cavity defects.
Impact of Perineural Invasion on Survival Outcomes in Oral Squamous Cell Carcinoma
Perineural invasion linked to poorer outcomes in oral squamous cell carcinoma
A meta-analysis of 23,580 patients confirms that perineural invasion is a potent independent predictor of poor survival and high recurrence …
A large review of over 23,000 patients shows that cancer cells spreading along nerves are linked to higher recurrence and lower survival rat…
AI-based MRI shows 0.82 AUC for detecting cervical lymph node metastases in oral squamous cell carcinoma
AI tools help detect lymph node spread in oral cancer
This meta-analysis of 548 patients evaluates AI-based MRI for detecting cervical lymph node metastases in oral squamous cell carcinoma. The …
Artificial intelligence may help doctors better identify if oral cancer has spread to lymph nodes before surgery.
Higher preoperative neutrophil-to-lymphocyte ratio predicts poorer survival in oral squamous cell carcinoma patients
High white blood cell ratios predict survival in oral cancer
This meta-analysis of 30 studies indicates that a higher preoperative neutrophil-to-lymphocyte ratio (NLR) is significantly associated with …
A high ratio of neutrophils to lymphocytes before surgery can help doctors predict survival outcomes for patients with oral squamous cell ca…
Deep Learning algorithms demonstrate potential for diagnosing oral potentially malignant disorders and squamous cell carcinoma
Artificial Intelligence Shows Potential for Detecting Oral Cancer
This meta-analysis evaluated the diagnostic accuracy of deep learning models using white light digital photographs to identify oral malignan…
New research shows that deep learning tools can help identify oral cancer and precancerous conditions using simple digital photos.
Ninjin’yoeito attenuates postoperative Prognostic Nutritional Index decline in patients with oral squamous cell carcinoma
Ninjin’yoeito may help patients with oral squamous cell carcinoma
This single-arm clinical trial evaluated the impact of Ninjin’yoeito on nutritional status in patients with oral squamous cell carcinoma und…
A small study suggests that Ninjin’yoeito could help maintain nutritional health in patients undergoing surgery for oral cancer.
Circulating miRNAs show high diagnostic accuracy for oral squamous cell carcinoma with AUC of approximately 0.90
Saliva and blood tests may help identify oral cancer
This systematic review and meta-analysis evaluated the diagnostic accuracy of circulating microRNAs in blood and saliva for oral squamous ce…
New data suggests that specific molecules in saliva and blood could help doctors more accurately identify patients with oral squamous cell c…
Hyperspectral imaging shows strong diagnostic performance for oral cancer detection in scoping review
Hyperspectral imaging shows promise for detecting oral cancer
This scoping review of 15 studies found that hyperspectral imaging (HSI) demonstrates strong diagnostic performance for detecting and charac…
A new review finds hyperspectral imaging can spot oral cancer with high accuracy, offering a non-contact alternative for margin assessment.