Research across Head and Neck Cancer
Related studies from across the Head and Neck Cancer family.
Molecular markers may improve risk assessment in oral potentially malignant disorders
Molecular tools may improve risk assessment for oral lesions
This narrative review examines the limitations of conventional histopathological grading for oral potentially malignant disorders (OPMDs) an…
A review suggests molecular methods could better assess risk for oral potentially malignant disorders where standard grading is unreliable.
Narrative review explores mitochondrial-targeted therapeutics for oral squamous cell carcinoma
New drug strategy targets mouth cancer's hidden power source
This narrative review discusses the potential of mitochondrial-targeted therapeutics in oral squamous cell carcinoma (OSCC). The authors syn…
Targeting the cell's power source could help overcome stubborn mouth cancer resistance.
Meta-analysis finds BCI_net prognostic for overall survival in oral squamous cell carcinoma
A new cancer test reads tumor cell chats to predict survival
This meta-analysis of 2 cohorts (TCGA-HNSC n=519, GSE65858 n=270) found that the BCI_net directional composite was independently associated …
Your cancer cells may be chatting with each other, and a new test that listens to those conversations could predict how aggressive the disea…
Narrative review explores Veillonella's dynamic role in oral squamous cell carcinoma
Oral bacteria shift early in cancer and vanish as tumors grow
This narrative review examines the role of Veillonella species in oral squamous cell carcinoma (OSCC). The authors report a dynamic, stage-d…
A specific mouth bacteria appears early in cancer development but disappears as tumors grow larger, suggesting it helps start the problem ra…
Meta-analysis finds frozen section reliable for tumor-free margins in OSCC
Surgeons rely on frozen sections to ensure clean cuts for oral cancer patients
This systematic review and meta-analysis of 19 studies (9 with complete data) assessed frozen section analysis for detecting tumor-free marg…
A new review confirms that frozen section analysis is a highly reliable way for surgeons to check if oral cancer has been fully removed duri…
Narrative review discusses targeting ferroptosis and cuproptosis in oral squamous cell carcinoma
New ideas target cell death pathways for oral cancer
This narrative review explores the potential of targeting ferroptosis and cuproptosis in patients with oral squamous cell carcinoma.
A review explores fresh ways to fight oral cancer by targeting specific cell death pathways. This approach offers new hope for patients with…
Iron and oxidative stress biomarkers linked to oral cancer recurrence after surgery
Iron levels and oxidative stress linked to cancer return in oral squamous cell carcinoma patients
This retrospective cohort study of 240 patients with oral squamous cell carcinoma who underwent radical surgery found that 36.7% experienced…
Among 240 oral cancer patients, high iron and oxidative stress markers were more common in those whose cancer came back after surgery.
Personalized swallowing rehab improves outcomes after oral cancer surgery
New Swallowing Therapy Helps Oral Cancer Patients Eat and Speak More Easily
This randomized controlled trial in 300 patients with oral squamous cell carcinoma found that a personalized swallowing rehabilitation progr…
Personalized swallowing therapy helps oral cancer patients recover faster, eat more naturally, and avoid dangerous complications like pneumo…
High NSUN3 expression linked to poor survival in oral squamous cell carcinoma
High NSUN3 protein makes oral cancer spread faster
This cohort study of 60 oral squamous cell carcinoma patients found that upregulated NSUN3 expression is an independent risk factor for poor…
Imagine waking up with a sore in your mouth that won't heal.
Review links oral microbiome dysbiosis to malignant transformation in oral lichen planus
Bacteria That Turn Harmful Mouth Sores Into Cancer
This narrative review synthesizes evidence regarding oral microbiome dysbiosis as a potential driver of malignant transformation in oral lic…
Changing the bad bacteria in your mouth could stop a painful sore from becoming cancer.
Classification framework shows 79% to 98% performance for oral squamous cell carcinoma on histopathological images
AI Learns to Ignore Stains to Spot Mouth Cancer
A computer-aided classification study evaluated a framework combining staining-bias suppression and structured multiple-instance aggregation…
New AI technology learns to ignore stain colors, helping doctors spot mouth cancer more accurately even when lab dyes vary.