Genomic instability markers show associations with malignant transformation in oral leukoplakias and proliferative verrucous leukaplakias
Genomic markers show links to cancer in oral leukoplakia
This systematic review of 34 observational studies analyzed genomic instability markers in 3,237 patients with oral leukakias and proliferat…
New research identifies specific DNA markers that may help predict when oral leukoplakia turns into cancer.
Meta-analysis of oxidative stress markers in oral leukoplakia versus healthy controls
High Oxidative Stress Found in Oral White Patches
This systematic review and meta-analysis pooled data from 12 studies comparing patients with oral leukoplakia to healthy controls.
White patches in the mouth show higher oxidative stress than healthy tissue, helping doctors spot dangerous changes before they become cance…
Research across Head and Neck Cancer
Related studies from across the Head and Neck Cancer family.
Submental Artery Island Flap Shows 16% Pooled Locoregional Recurrence in Oral Cavity Reconstruction
Submental artery island flap is a safe option for oral cancer
This meta-analysis pooled data on the submental artery island flap (SAIF) for oral cavity defects after oral squamous cell carcinoma resecti…
A specific surgical technique called the submental artery island flap shows a low recurrence rate for patients with oral cavity defects.
Impact of Perineural Invasion on Survival Outcomes in Oral Squamous Cell Carcinoma
Perineural invasion linked to poorer outcomes in oral squamous cell carcinoma
A meta-analysis of 23,580 patients confirms that perineural invasion is a potent independent predictor of poor survival and high recurrence …
A large review of over 23,000 patients shows that cancer cells spreading along nerves are linked to higher recurrence and lower survival rat…
AI-based MRI shows 0.82 AUC for detecting cervical lymph node metastases in oral squamous cell carcinoma
AI tools help detect lymph node spread in oral cancer
This meta-analysis of 548 patients evaluates AI-based MRI for detecting cervical lymph node metastases in oral squamous cell carcinoma. The …
Artificial intelligence may help doctors better identify if oral cancer has spread to lymph nodes before surgery.
Higher preoperative neutrophil-to-lymphocyte ratio predicts poorer survival in oral squamous cell carcinoma patients
High white blood cell ratios predict survival in oral cancer
This meta-analysis of 30 studies indicates that a higher preoperative neutrophil-to-lymphocyte ratio (NLR) is significantly associated with …
A high ratio of neutrophils to lymphocytes before surgery can help doctors predict survival outcomes for patients with oral squamous cell ca…
Deep Learning algorithms demonstrate potential for diagnosing oral potentially malignant disorders and squamous cell carcinoma
Artificial Intelligence Shows Potential for Detecting Oral Cancer
This meta-analysis evaluated the diagnostic accuracy of deep learning models using white light digital photographs to identify oral malignan…
New research shows that deep learning tools can help identify oral cancer and precancerous conditions using simple digital photos.
Ninjin’yoeito attenuates postoperative Prognostic Nutritional Index decline in patients with oral squamous cell carcinoma
Ninjin’yoeito may help patients with oral squamous cell carcinoma
This single-arm clinical trial evaluated the impact of Ninjin’yoeito on nutritional status in patients with oral squamous cell carcinoma und…
A small study suggests that Ninjin’yoeito could help maintain nutritional health in patients undergoing surgery for oral cancer.
Circulating miRNAs show high diagnostic accuracy for oral squamous cell carcinoma with AUC of approximately 0.90
Saliva and blood tests may help identify oral cancer
This systematic review and meta-analysis evaluated the diagnostic accuracy of circulating microRNAs in blood and saliva for oral squamous ce…
New data suggests that specific molecules in saliva and blood could help doctors more accurately identify patients with oral squamous cell c…
Hyperspectral imaging shows strong diagnostic performance for oral cancer detection in scoping review
Hyperspectral imaging shows promise for detecting oral cancer
This scoping review of 15 studies found that hyperspectral imaging (HSI) demonstrates strong diagnostic performance for detecting and charac…
A new review finds hyperspectral imaging can spot oral cancer with high accuracy, offering a non-contact alternative for margin assessment.
Oral diseases stem from disrupted host-microbiome-immune balance, narrative review argues
New research explores how oral bacteria drive gum disease
This narrative review argues that periodontitis, dental caries, and oral squamous cell carcinoma should be understood as disorders of host-m…
Oral health depends on a delicate balance between your immune system, tissue barriers, and the trillions of microbes living in your mouth.
Molecular markers may improve risk assessment in oral potentially malignant disorders
Molecular tools may improve risk assessment for oral lesions
This narrative review examines the limitations of conventional histopathological grading for oral potentially malignant disorders (OPMDs) an…
A review suggests molecular methods could better assess risk for oral potentially malignant disorders where standard grading is unreliable.
Narrative review explores mitochondrial-targeted therapeutics for oral squamous cell carcinoma
New drug strategy targets mouth cancer's hidden power source
This narrative review discusses the potential of mitochondrial-targeted therapeutics in oral squamous cell carcinoma (OSCC). The authors syn…
Targeting the cell's power source could help overcome stubborn mouth cancer resistance.
Meta-analysis finds BCI_net prognostic for overall survival in oral squamous cell carcinoma
A new cancer test reads tumor cell chats to predict survival
This meta-analysis of 2 cohorts (TCGA-HNSC n=519, GSE65858 n=270) found that the BCI_net directional composite was independently associated …
Your cancer cells may be chatting with each other, and a new test that listens to those conversations could predict how aggressive the disea…