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Home › Conditions › Overactive Bladder

Overactive Bladder

3 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Overactive Bladder

103 trials tracked for Overactive Bladder: 58 in phase 3 or 4 and 19 with published results. The most-cited published study has 220 citations.

103Trials tracked
58Phase 3 & 4
0Recruiting
19With published results
Phase distribution
Phase 4 29 Phase 3 29 Phase 2 11 Phase 1 3 Other / NA 31
  1. Phase 3 Anticholinergic vs. Botox Comparison Study Completed · 220 cited
  2. Phase 4 InSite for Over Active Bladder Completed · 202 cited
  3. Phase 3 A Multinational Study Comparing the Long-term Efficacy and Safety of Two Medicines, Solifenacin Succinate and Mirabegron Taken Together, or Separately, in Subjects With Symptoms of Overactive Bladder Completed · 110 cited
  4. Phase 3 Pilot Study of Mirabegron in Pediatric Patients With Overactive Bladder Completed · 97 cited
  5. Phase 4 Investigation of the Effect of the Female Urinary Microbiome on Incontinence Completed · 84 cited
  6. Phase 3 Combined Behavioral and Drug Treatment of Overactive Bladder in Men Completed · 67 cited
Show 44 more trials
  1. Phase 3 An Extension Study to Examine the Safety and Tolerability of a New Drug in Patients With Symptoms of Overactive Bladder (OAB). Completed · 43 cited
  2. Phase 3 This Was a Multinational Study Comparing the Efficacy and Safety of Two Medicines , Solifenacin Succinate and Mirabegron Taken Together, or Separately, or a Mock Treatment (Placebo) in Subjects With Symptoms of Overactive Bladder Completed · 26 cited
  3. Phase 3 A Study to Examine the Safety and Efficacy of a New Drug in Patients With Symptoms of Overactive Bladder (OAB) Completed · 26 cited
  4. Phase 4 OnabotulinumtoxinA (BOTOX®) Treatment for Urinary Incontinence in Patients With Overactive Bladder Completed · 17 cited
  5. Phase 4 Is 10 Injections of Bladder Botox Less Painful Than 20 Injections? Completed · 13 cited
  6. Phase 4 Mirabegron and Urinary Urgency Incontinence Completed · 10 cited
  7. Phase 4 Fall Prevention in Older Adults With OAB Completed · 5 cited
  8. Phase 4 A Phase 4 Study to Evaluate the Efficacy, Safety, and Tolerability of Mirabegron in Male Subjects With Overactive Bladder (OAB) Symptoms, While Taking the Alpha Blocker for Benign Prostatic Hypertrophy (BPH) Completed · 5 cited
  9. Phase 3 Behavioral or Solifenacin Therapy for Urinary Symptoms in Parkinson Disease Completed · 4 cited
  10. Phase 4 Procedural Discomfort Related to Number of Intradetrusor Botox Injections Completed · 3 cited
  11. Phase 4 Posterior Tibial Nerve Stimulation (PTNS) Plus Mirabegron to Treat Refractory OAB Symptoms (PTNS-M Study) Completed · 2 cited
  12. Phase 4 Minimizing Pain During Office Intradetrussor Botox Injection Completed · 1 cited
  13. Phase 3 Study to Evaluate the Efficacy, Safety and Tolerability of Vibegron in Men With Overactive Bladder (OAB) Symptoms on Pharmacological Therapy for Benign Prostatic Hyperplasia (BPH) Completed
  14. Phase 4 A Study to Evaluate the Effect of Mirabegron + Solifenacin in Overactive Bladder Patients Completed
  15. Phase 4 Reduction of Bladder Injection Pain With Belladonna Opiate Suppository Completed
  16. Phase 4 Mirabegron in Parkinson Disease and Impaired Cognition Completed
  17. Phase 4 A Study to Evaluate the Efficacy, Safety, and Tolerability of Mirabegron in Men With OAB Symptoms While Taking Tamsulosin Hydrochloride for Lower Urinary Tract Symptoms (LUTS) Due to Benign Prostatic Hyperplasia (BPH) Completed
  18. Phase 4 Prophylactic Antibiotic Administration for Bladder OnabotulinumtoxinA Injection Completed
  19. Phase 4 Intradetrusor Botulinum Toxin A for OAB Via 1 Versus 10 Injections: A Randomized Clinical Trial Completed
  20. Phase 4 A 12 Week Study to Confirm the Effectiveness of 8mg of Fesoterodine Compared to 4mg of Fesoterodine Completed
  21. Phase 4 Sanctura Muscarinic Receptor Antagonist Resists Transport (SMART) Trial Completed
  22. Phase 4 Study of 2 Doses of Solifenacin Succinate in Female Subjects With Overactive Bladder. Completed
  23. Phase 4 Overactive Bladder Innovative Therapy Trial (OrBIT) Completed
  24. Phase 4 Trospium Chloride XR in Obese Female Patients With Overactive Bladder Completed
  25. Phase 4 A Trial To Evaluate The Efficacy And Safety Of Fesoterodine In Patients With Symptoms Of Overactive Bladder Including Nocturnal Urinary Urgency Completed
  26. Phase 4 The Efficacy of Solifenacin With or Without Tamsulosin in Adult Women With Overactive Bladder (OAB) Completed
  27. Phase 4 Bringing Simple Urge Incontinence Diagnosis & Treatment to Providers (BRIDGES) Completed
  28. Phase 4 Study of Urgent PC Versus Sham Effectiveness in Treatment of Overactive Bladder Symptoms Completed
  29. Phase 4 Efficacy of Sanctura XR (Trospium Chloride) for Reducing Overactive Bladder Symptoms in Female Subjects Refractory to Detrol LA (Tolterodine Tartrate Extended Release) Daily Completed
  30. Phase 4 Sanctura Muscarinic Receptor Antagonist Resists Transport (SMART-II) Trial Completed
  31. Phase 4 A Study Of Efficacy And Safety Of Fesoterodine In Vulnerable Elderly Subjects With Overactive Bladder Completed
  32. Phase 4 Study to Compare the Safety and Efficacy of Solifenacin With Oxybutynin for the Treatment of Overactive Bladder (VECTOR) Completed
  33. Phase 3 Add-on Mirabegron in Pediatric Patients With Refractory Overactive Bladder Completed
  34. Phase 3 Botox for the Treatment of Overactive Bladder Secondary to Benign Prostatic Obstruction Completed
  35. Phase 3 Efficacy and Safety Evaluating Study to Compare Uritos® (Imidafenacin) and Urotol® (Tolterodine) for Treatment of Overactive Bladder. Completed
  36. Phase 3 Study to Gather Information About the Actual Use of an Adhesive Patch Placed on the Skin to Deliver Oxytrol Through the Skin Into the Bloodstream. Completed
  37. Phase 3 Extension Study of Vibegron in Men With Overactive Bladder (OAB) Symptoms on Pharmacological Therapy for Benign Prostatic Hyperplasia Completed
  38. Phase 3 Long Term Study To Evaluate the Safety, Tolerability and Efficacy of Fesoterodine for Overactive Bladder. Completed
  39. Phase 3 Study of Botulinum Toxin Type A for the Treatment of Patients With Idiopathic Overactive Bladder With Urinary Incontinence Completed
  40. Phase 3 Fesoterodine Flexible Dose Study Completed
  41. Phase 3 Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Neurogenic Overactive Bladder Completed
  42. Phase 3 An Implantable Microstimulator for the Chronic Treatment of Urinary Urgency-Frequency Syndrome Completed
  43. Phase 3 A Clinical Trial To Assess Fesoterodine On Treatment Satisfaction And Symptom Improvement In Overactive Bladder Patients Completed
  44. Phase 3 A Long-term Follow-up Study of Botulinum Toxin Type A in Patients With Overactive Bladder as a Result of Spinal Injury or Multiple Sclerosis Completed

Showing the 50 most-cited and recently-updated of 103 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Auricular thumbtack needle therapy plus behavioral therapy improved overactive bladder and anxiety scores in 118 women over 6 weeks
Psychiatry RCT
Auricular thumbtack needle therapy plus behavioral therapy improved overactive bladder and anxiety scores in 118 women over 6 weeks Thumbtack therapy plus behavioral care improved bladder and anxiety symptoms in women
This randomized controlled trial enrolled 118 female patients with mild to moderate overactive bladder and anxiety symptoms.
Women with overactive bladder and anxiety saw better symptom scores and sleep after auricular thumbtack needle therapy combined with behavio…
Apr 25, 2026
TTNS plus behavior therapy reduces urgency and nocturia in older women with OAB
Anesthesiology & Pain Medicine RCT
TTNS plus behavior therapy reduces urgency and nocturia in older women with OAB Small study finds nerve stimulation plus therapy may help older women with overactive bladder
A small RCT in 38 older women with OAB compared behavior therapy (BT) alone to BT plus transcutaneous tibial nerve stimulation (TTNS).
Adding gentle ankle nerve stimulation to standard bladder training helped older women reduce urgent leakage and nighttime urination more tha…
Apr 8, 2026
Relaxing environment reduces anxiety before office intradetrusor chemodenervation in women with OAB
Psychiatry RCT
Relaxing environment reduces anxiety before office intradetrusor chemodenervation in women with OAB Relaxing environment with lavender and music reduces anxiety before bladder procedure
A single-center randomized trial in 80 women undergoing office intradetrusor chemodenervation for overactive bladder found that a relaxing e…
A calming room with lavender scent and soft music significantly lowered anxiety for women before their bladder procedure compared to a typic…
Apr 3, 2026

Questions about Overactive Bladder

How does a calming environment affect anxiety for overactive bladder patients?

Creating a calming environment with soft lighting, music, and lavender scent can significantly lower anxiety levels in women with overactive bladder before medical procedures.

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Does a relaxing environment reduce anxiety before overactive bladder treatment?

A relaxing environment with lavender, music, and dim lighting significantly reduces anxiety before overactive bladder procedures like Botox injections.

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Can transcutaneous tibial nerve stimulation reduce urgency in older women with overactive bladder?

Yes, transcutaneous tibial nerve stimulation (TTNS) combined with behavioral therapy reduces urgency and nighttime bathroom trips in older women with overactive bladder.

Full answer →