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Neurology
Review of P-BANN framework for Parkinson disease proteomics data analysis
New tool helps map proteins in Parkinson disease
This methodological review synthesizes the application of the P-BANN framework, a biologically annotated neural network model, to proteomics…
A new method finds specific protein groups linked to disease pathways in Parkinson disease, offering a fresh way to study the condition.
medRxiv
May 1, 2026
Neurology
RCT
Soft robotic exoskeleton training improved gait speed and stride length in people with Parkinson disease over four weeks.
Soft robotic suits helped people with Parkinson disease walk faster and move better.
This randomized controlled pilot study enrolled 56 people with Parkinson disease. Participants received conventional rehabilitation combined…
A pilot study found that adding soft robotic exoskeleton training to standard rehab improved walking speed, stride length, and balance in pe…
Apr 29, 2026
Neurology
Review of iRBD biomarker-positive participants shows higher rates of cognitive and autonomic symptoms compared to healthy controls.
Sleep disorder signals hidden brain changes before official Parkinson's diagnosis
This observational review analyzes data from 197 iRBD participants with positive CSF neuronal alpha-synuclein seed amplification assay and 1…
People with this specific sleep disorder show clear signs of brain changes that happen before doctors officially diagnose Parkinson's diseas…
medRxiv
Apr 28, 2026
Neurology
Cross-sectional review links illness perceptions to quality of life variance in Parkinson disease patients
Parkinson’s patients’ mindset affects quality of life more than symptoms
This cross-sectional study reviews data from 58 people with idiopathic Parkinson disease across multiple centers. The authors assess how mot…
Many Parkinson’s patients suffer more from how they think about their illness than from their physical symptoms, a new look at daily life re…
medRxiv
Apr 28, 2026
Genetics & Precision Medicine
Genomic and proteomic investigation suggests genetic liability to smoking initiation may protect against Parkinson disease
Could genes tied to smoking start help protect against Parkinson disease?
This genomic and proteomic investigation explores genetic links between smoking traits and Parkinson disease. It finds a protective effect o…
Genes linked to starting smoking may lower Parkinson disease risk, pointing to new smoke-free treatment targets without encouraging the harm…
medRxiv
Apr 20, 2026
Cardiology
Pilot Abstract Reports Artificial Baroreflex System With DBS in Parkinson Disease Patients
Brain Zaps May Soon Stabilize Blood Pressure
This pilot study abstract involving 3 patients with Parkinson disease reports low certainty due to the small sample size. Results indicate a…
A new brain stimulation system could stop dangerous blood pressure crashes that cause Parkinson's patients to faint when standing up.
medRxiv
Apr 19, 2026
Neurology
Meta-analysis
Parkinson disease associated with higher cerebral small vessel disease burden compared to healthy controls in this meta-analysis.
Parkinson's May Be a Blood Vessel Problem Too, New Review Hints
This systematic review and meta-analysis of cross-sectional studies compared adults with idiopathic Parkinson disease to healthy controls. R…
Parkinson's may be partly a disease of the brain's plumbing, not just its dopamine wiring — and that could reshape how doctors think about g…
Apr 13, 2026
Neurology
Parkinson disease death rates increased in US adults 65+ from 1999 to 2017
Parkinson's disease death rates rose in older U.S. adults from 1999 to 2017
An observational analysis of US national vital statistics found age-adjusted Parkinson disease death rates increased from 41.7 to 65.3 per 1…
Parkinson's disease death rates for older U.S. adults rose from 41.7 to 65.3 per 100,000 people between 1999 and 2017.
CDC
Apr 3, 2026