Vascular smooth muscle cell immune interactions drive remodeling across cardiovascular diseases
How blood vessel cells drive heart disease and high blood pressure
This narrative review synthesizes mechanisms of VSMC-immune interactions in atherosclerosis, hypertension, aortic aneurysms, and arteritis. …
A new review reveals how blood vessel cells change in heart disease, high blood pressure, and more.
Mechanical shear stress influences endothelial RNA methylation in atherosclerosis and pulmonary arterial hypertension
Mechanical forces on blood vessel cells may change how they repair themselves
This narrative review examines the interplay between hemodynamic shear stress and epitranscriptomic mechanisms in endothelial cells. The aut…
New review suggests blood flow forces might alter how RNA works in cells lining our vessels, potentially affecting heart and lung health.
Narrative review highlights limited data on connective tissue disease-associated PAH in Han Chinese populations
New data reveals how lung pressure risks differ for Chinese patients with connective tissue disease
This narrative review examines connective tissue disease-associated pulmonary arterial hypertension, specifically systemic sclerosis-associa…
A new review shows that lung pressure risks for Chinese patients with connective tissue disease differ from Western populations and require …
Systematic review of immunosuppression for SLE-associated intestinal pseudo-obstruction
SLE Can Shut Down the Gut — But It Might Be Reversible
This review synthesized 43 cases of SLE-associated intestinal pseudo-obstruction.
Lupus can paralyze the gut without a blockage, but early treatment with immunosuppressives often reverses this dangerous complication.
Inflammatory and metabolic markers differ across systemic sclerosis lung phenotypes in retrospective study
Scleroderma Lung Damage May Leave Hidden Clues in Blood
A retrospective cross-sectional study of 314 SSc inpatients found higher inflammatory markers (ESR, hs-CRP, CRP/albumin ratio, SII) and anti…
Routine blood tests may soon reveal hidden lung damage patterns in scleroderma patients, helping doctors spot dangerous complications before…
FDA Approves Winrevair for Pulmonary Arterial Hypertension (PAH) in Adults
FDA approves a new treatment for a serious lung condition called pulmonary arterial hypertension
The FDA has approved Winrevair for the treatment of adults with pulmonary arterial hypertension (PAH, WHO Group 1) to improve exercise capac…
A new FDA-approved injection helps adults with pulmonary arterial hypertension exercise longer, improve daily life, and lower the risk of ho…
Parenteral Treprostinil Shows Efficacy in Pediatric PAH, Meta-Analysis Confirms
Can parenteral treprostinil help kids with pulmonary arterial hypertension?
Meta-analysis of 143 patients shows parenteral treprostinil benefits in pediatric PAH. Data supports efficacy and safety.
Parenteral treprostinil shows clear treatment benefits and safety for children with pulmonary arterial hypertension, offering hope for famil…
Research across Hypertension
Related studies from across the Hypertension family.
Evaluating the Impact of Digital Health Interventions on Chronic Disease Self-Care Outcomes
Digital health tools show mixed results for managing chronic diseases
Digital tools show promise for heart failure monitoring but lack consistent evidence for improving medication adherence or general diabetes …
New data shows that while digital tools like apps can help heart failure patients monitor their health, they may not improve medication habi…
Ambulatory hypertension in pediatric chronic kidney disease patients increases risk of left ventricular hypertrophy
High Blood Pressure Linked to Heart Changes in Children
This meta-analysis of 51 studies involving 6509 children with chronic kidney disease found that ambulatory hypertension is associated with i…
New data shows a strong link between high blood pressure and heart muscle thickening in children with chronic kidney disease.
Pharmacist-led telepharmacy may improve medication adherence and reduce blood pressure in patients with NCDs
Pharmacist Led Telepharmacy May Improve Medication Adherence For Chronic Illness
This systematic review analyzed 21 trials involving 5440 participants to evaluate pharmacist-led telepharmacy for managing non-communicable …
Remote pharmacist services through phone or video may help patients with high blood pressure and diabetes stick to their daily medication pl…
Individualized six-phase antithrombotic strategy leads to left ventricular thrombus resolution and neurological recovery
New strategy helps manage heart blood clots after heart attack
This case report describes an individualized six-phase antithrombotic strategy for a 27-year-old male with myocardial infarction, stroke, hy…
A tailored six-phase treatment plan helped a young man recover fully from a stroke and heart attack while successfully clearing dangerous bl…
Multi-target therapies may address combined hypertension and dyslipidemia pathophysiology
Multi-Target Therapies May Address Combined Hypertension and High Cholesterol
This systematic review synthesizes evidence on synergistic mechanisms of hypertension and dyslipidemia, highlighting the RAAS/PPAR axis, AMP…
Combining treatments like statins and RAAS inhibitors may offer a more precise way to manage both high blood pressure and cholesterol levels…
Bedtime antihypertensive dosing shows no cardiovascular benefit over morning dosing
Bedtime vs. Morning Blood Pressure Meds: No Clear Winner
A meta-analysis of randomized trials compared bedtime versus morning administration of antihypertensives. No evidence of a difference in maj…
Taking blood pressure medication at bedtime did not reduce heart attacks, strokes, or deaths more than morning dosing in a large analysis of…
Preoperative comorbidities linked to reduced weight loss after metabolic and bariatric surgery in adults
Pre-existing health conditions may slightly reduce weight loss after surgery
A meta-analysis of twenty-three studies reveals that mental illness, diabetes, and sleep apnea are associated with slightly lower weight los…
Adults with mental illness or diabetes before surgery saw slightly less weight loss. Other conditions like high blood pressure did not affec…
Renal denervation value framework prioritizes efficacy and safety for Chinese hospital procurement
Experts build framework to assess renal denervation therapy value in China
This narrative review constructs a comprehensive value assessment framework for renal denervation (RDN) therapy in Chinese hospitals. The fr…
A new framework helps Chinese hospitals evaluate renal denervation therapy by weighing factors like safety, efficacy, and patient value.
Eating later in the biological day is associated with impaired glucose regulation and reduced insulin sensitivity
Eating later in the day is linked to worse blood sugar and heart health markers
This narrative review examines chrononutrition in obesity, type 2 diabetes, hypertension, and cardiovascular disease. Findings indicate that…
A review suggests eating later in the biological day is associated with impaired glucose regulation and reduced insulin sensitivity in peopl…
Bosentan lowers treatment failure risk in neonates with persistent pulmonary hypertension of the newborn by 73%
Bosentan therapy lowers treatment failure for newborns with persistent lung pressure issues
This systematic review and meta-analysis evaluated bosentan for persistent pulmonary hypertension of the newborn. The pooled analysis showed…
A new analysis shows bosentan therapy reduces treatment failure for newborns with persistent pulmonary hypertension compared to control trea…
Hypertension care cascade under dual guideline criteria was analyzed in 238,738 adults from Peru
Peru adults with high blood pressure face gaps in standard care guidelines
This repeated cross-sectional analysis examined the hypertension care cascade under dual guideline criteria (2023 ESH and 2025 ACC/AHA) in 2…
A look at 238,738 adults in Peru shows how often high blood pressure care falls short of current expert recommendations.
Renal denervation combined with pulmonary vein isolation increases freedom from atrial fibrillation risk in resistant hypertension patients
Renal denervation may help resistant hypertension patients with heart issues
This systematic review and meta-analysis evaluated renal denervation in patients with resistant hypertension. The pooled analysis included 8…
A meta-analysis suggests renal denervation improves heart and sleep markers in patients with resistant hypertension, though larger trials ar…
Questions about Pulmonary Arterial Hypertension
Does the new drug Winrevair improve exercise capacity for people with Pulmonary Arterial Hypertension?
Yes, the drug Winrevair (sotatercept) improves exercise capacity in adults with pulmonary arterial hypertension by increasing distance walked and oxygen use.
Full answer →Can parenteral treprostinil help children with pediatric Pulmonary Arterial Hypertension based on recent studies?
Yes, recent studies show parenteral treprostinil can improve outcomes in children with PAH, though evidence is from observational studies, not large trials.
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