Intravenous nicorandil did not significantly reduce primary composite outcomes in patients with STEMI
Trial shows intravenous nicorandil does not improve heart attack outcomes
This randomized controlled trial of 1,503 patients with STEMI found no significant difference in the primary composite outcome between intra…
A large trial of over 1,500 patients found that the drug nicorandil did not improve primary outcomes for those with a heart attack.
Functional Coronary Angiography Improves Clinical Outcomes in Multivessel STEMI Patients
Physiology guided heart procedures show lower risk of major events
Physiology-guided revascularization significantly reduces major adverse cardiac events and improves safety profiles compared to traditional …
A large international trial shows that using functional imaging to guide heart artery procedures may lower the risk of stroke and heart atta…
Pressure optimization protocol improves reperfusion success and reduces postdilation in STEMI patients
New stenting technique improves blood flow after heart attacks
This multicenter randomized trial of 607 patients undergoing primary PCI for STEMI found that a pressure optimization protocol (POP) signifi…
A new pressure optimization method during heart surgery helps restore blood flow faster and reduces the need for extra procedures.
Impella CP Reduces Escalation Need in STEMI Cardiogenic Shock
Trial shows micro-axial flow pump reduces escalation rates
In non-comatose STEMI cardiogenic shock patients, Impella CP reduced escalation to higher tMCS vs standard care, but escalated patients had …
A new analysis shows that using a specific heart pump can delay the need for more invasive treatments in patients with severe heart failure.
Tocilizumab shows early anti-inflammatory effects but no significant clinical benefit in STEMI or NSTEMI
Tocilizumab shows early signs of heart protection in heart attacks
This meta-analysis of randomized controlled trials evaluated tocilizumab for patients with STEMI and NSTEMI. While the intervention showed a…
A new review looks at how the drug tocilizumab affects patients with heart attacks, showing some early signs of reduced inflammation.
Staged revascularization shows no significant difference versus immediate revascularization for major adverse cardiovascular events in STEMI and MVD patients
Timing of heart surgery does not change survival for a specific heart attack group
This meta-analysis reviewed 5077 patients with ST-segment elevation myocardial infarction and multivessel coronary artery disease comparing …
A large review found that waiting for staged heart surgery did not improve survival or reduce heart attacks compared to immediate surgery fo…
Prehospital unfractionated heparin bolus improved TIMI flow in STEMI without increasing bleeding risk
Pretreatment with UFH improves artery flow for STEMI patients without extra bleeding risk
This single-center randomized trial evaluated pretreatment with unfractionated heparin in patients with ST-segment-elevation myocardial infa…
Giving unfractionated heparin early at first medical contact improved artery flow in heart attack patients without increasing bleeding risk.
Phase 2 pilot study evaluates ticagrelor monotherapy safety after stenting for acute MI
Can a single blood thinner prevent heart attacks after stent placement?
A single-center, single-arm, prospective phase II pilot study of 200 patients assessed the initial safety of ticagrelor monotherapy after co…
A new pilot study tests if one blood thinner alone can safely prevent heart attacks and stent clots after stent placement for heart attack p…
Questions about STEMI
Is ticagrelor monotherapy safe for patients who have just had a STEMI?
Small pilot trials in STEMI patients suggest ticagrelor monotherapy right after primary PCI may reduce bleeding without a clear rise in ischemic events, but the evidence is too limited to call it proven safe.
Full answer →Does a pressure optimization protocol improve reperfusion for STEMI patients?
Yes. A large randomized trial found that a pressure optimization protocol during primary PCI for STEMI improved reperfusion success compared with conventional rapid inflation-deflation stenting [1][6].
Full answer →