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Home › Conditions › Tetanus

Tetanus

Part of Clostridioides difficile infection

3 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Tetanus

102 trials tracked for Tetanus: 85 in phase 3 or 4 and 20 with published results. The most-cited published study has 96 citations.

102Trials tracked
85Phase 3 & 4
0Recruiting
20With published results
Phase distribution
Phase 4 30 Phase 3 55 Phase 2 13 Phase 1 2 Other / NA 2
  1. Phase 4 Immunogenicity & Reactogenicity of Boostrix 10 Years After Previous Booster Vaccination. Completed · 96 cited
  2. Phase 4 Immunogenicity & Reactogenicity of Boostrix 10 Years After Previous Booster Vaccination in Study NCT01267058 Completed · 64 cited
  3. Phase 3 Immunogenicity, Safety of GSKs Tdap Vaccine Boostrix When Coadministered With GSKs Influenza Vaccine Fluarix in Adults Completed · 62 cited
  4. Phase 3 Safety and Immunogenicity of GSK's Tdap Vaccine (Boostrix) in Adults Aged 19 to 64 Years Completed · 57 cited
  5. Phase 4 Safety and Immunogenicity in Adults of Revaccination With Adacel® Vaccine 10 Years After a Previous Dose Completed · 37 cited
  6. Phase 4 US-licensed Combined Vaccine Against Tetanus & Diphtheria, Given With US-licensed Vaccine Against Meningococcal Disease Completed · 28 cited
Show 44 more trials
  1. Phase 4 Immunogenicity and Safety Study of Infanrix Hexa in Healthy Infants Born to Mothers Vaccinated With Boostrix™ During Pregnancy or Immediately Post-delivery Completed · 28 cited
  2. Phase 4 Safety and Immunogenicity of a Booster Dose of GSK Biological's Boostrix-Polio Vaccine Completed · 26 cited
  3. Phase 3 Immunogenicity and Safety of Boostrix Polio Vaccine as a Booster Dose in 5 to 6-year-old Children. Completed · 19 cited
  4. Phase 3 Non-inferiority of GSK Biologicals' DTPw-HBV/Hib Compared to Two Formulations of GSK Biologicals' DTPw-HBV/Hib Completed · 18 cited
  5. Phase 3 Immunogenicity and Safety of GSK Biologicals' Boostrix Polio Vaccine in 3 and 4-year-old Children Completed · 16 cited
  6. Phase 3 Immunogenicity and Safety Study of Proquad® and Infanrix® Hexa When Administered Concomitantly (V221-035) Completed · 13 cited
  7. Phase 4 Evaluation of Immunogenicity and Safety of a Booster Dose of Infanrix Hexa™ in Healthy Infants Born to Mothers Vaccinated With Boostrix™ During Pregnancy or Immediately Post-delivery Completed · 12 cited
  8. Phase 4 Immunogenicity and Safety of Booster Dose of BoostrixTM Polio Vaccine in Previously Boosted Adults Completed · 11 cited
  9. Phase 4 Immunogenicity and Safety of GSK Biologicals' Infanrix Hexa in Infants Completed · 10 cited
  10. Phase 3 A Study to Assess the Immunogenicity and Safety of GSK Biologicals' Infanrix-IPV/Hib Vaccine Administered as a Three-dose Vaccination Course at 3, 4.5 and 6 Months of Age and a Booster Dose at 18 Months of Age in Healthy Infants in Russia Completed · 6 cited
  11. Phase 4 Study of Adacel® Vaccine Administered to Persons 10 Years of Age Completed · 5 cited
  12. Phase 4 Regulatory Post-Marketing Surveillance Study for TETRAXIM™ Completed · 5 cited
  13. Phase 3 Confirmatory Study of BK1310 in Healthy Infants Completed · 1 cited
  14. Phase 4 Immunogenicity and Safety of BoostrixTM Using a New Syringe in 10 to 15-year Old Adolescents Completed
  15. Phase 4 Study to Evaluate Antibody Persistence in Children Previously Vaccinated With Infanrix Hexa™ or Infanrix-IPV/Hib™ Completed
  16. Phase 4 Post Marketing Surveillance for ADACEL™ in South Korea Completed
  17. Phase 4 Assess the Safety & Reactogenicity of DTPa-IPV/Hib Vaccine Administered at 3, 4, 5 & 18 Mths of Age, in Healthy Infants Completed
  18. Phase 4 Tdap Vaccine in Post-Partum Women Completed
  19. Phase 4 PFAS Exposure and Immune Response to Vaccination in Adults Completed
  20. Phase 4 Post-licensure, Modified Double-blind, Multi-center Study Evaluating Safety and Immunogenicity of ADACEL® and BOOSTRIX® Completed
  21. Phase 4 Evaluation of Boostrix™10 Years After Previous Booster Vaccination Completed
  22. Phase 4 A Trial to Evaluate the Safety and Immunogenicity of ADACEL® Vaccine in Persons 65 Years of Age and Older Completed
  23. Phase 4 Canadian Manufactured Tetanus and Diphtheria Toxoids Adsorbed (Td) Vaccine Compared With U.S. Manufactured Td Completed
  24. Phase 4 Study to Assess if Quinvaxem Can be Interchanged With Other Pentavalent Vaccines During Standard Childhood Vaccination Completed
  25. Phase 4 Descriptive, Open-label, Multicenter Study of the Safety of Redosing With ADACEL® Vaccine Completed
  26. Phase 4 Study of Menactra® in Healthy Subjects at 9 Months and Concomitantly With Pentacel® at 15 to 18 Months of Age Completed
  27. Phase 4 Immunogenicity of Adacel® and BOOSTRIX® Vaccines in Adolescents Completed
  28. Phase 4 Study of DAPTACEL® Administered as a 5th Dose in 4 to 6-Year-Old Children Previously Immunized With PENTACEL™ Completed
  29. Phase 4 Immune Responses in Adults to Revaccination With ADACEL® 10 Years After a Previous Dose Completed
  30. Phase 4 Study of Menactra® in US Adolescents When Administered Concomitantly With Tdap Vaccine Completed
  31. Phase 4 Post-marketing Evaluation of Reactions Following Receipt of Recommended Adolescent Pertussis Vaccine Completed
  32. Phase 4 Study of a New Formulation of DTPa-HBV-IPV/Hib Vaccine Administered as a Booster Dose to 18-23 Months Old Children Completed
  33. Phase 3 Study of BK1301 (DTaP Vaccine) as a Booster in Adolescents Completed
  34. Phase 3 Safety of a Booster Dose of GlaxoSmithKline (GSK) Biologicals' Boostrix™ Vaccine in Healthy Vietnamese Children Completed
  35. Phase 3 Safety of DTPa-IPV/Hib & DTPa-HBV-IPV/Hib, Followed by DTPa-IPV/Hib Vaccine in Infants Who Received Hepatitis B Vaccine Completed
  36. Phase 3 Study to Assess Safety & Immunogenicity of GSK Biologicals' DTPa/Hib Vaccine vs Separate Administration of DTPa and Hib. Completed
  37. Phase 3 Immune Memory of DTPw-HBV/Hib Vaccine Following Primary Vaccination, Immuno & Reacto of a Booster Dose Given in Infants Completed
  38. Phase 3 Safety Study of Tritanrix-HepB/Hib-MenAC, Tritanrix-HepB/Hiberix, and Mencevax ACWY Vaccines in Children Completed
  39. Phase 3 Safety Study of GSK Biologicals' DTPa-IPV/Hib (Infanrix™-IPV/Hib) Completed
  40. Phase 3 Immunogenicity and Safety Study of GSK Biologicals' Infanrix-IPV+Hib™ Vaccine Completed
  41. Phase 3 Immunogenicity and Safety Study of Booster Dose of GSK Biologicals' IPV (Poliorix™) and DTPa/Hib (Infanrix+Hib™) Vaccine Completed
  42. Phase 3 Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Boostrix™ Vaccine in Previously Boosted Young Adults Completed
  43. Phase 3 Study to Determine the Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals; Infanrix Hexa at 2, 4 and 6 Months of Age in Healthy Infants Completed
  44. Phase 3 Response to GSK Biologicals' Tritanrix-HepB/Hib-MenAC Vacc (4th Dose) at 15-24m & Mencevax ACWY at 24-30m Completed

Showing the 50 most-cited and recently-updated of 102 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
ACIP updates adult vaccination recommendations, allowing Tdap or Td in more scenarios
Allergy & Immunology
ACIP updates adult vaccination recommendations, allowing Tdap or Td in more scenarios New vaccine rules give adults more options for tetanus and whooping cough protection
The Advisory Committee on Immunization Practices has updated recommendations for adult vaccination in the United States.
Adults in the U.S. now have more options for their tetanus shots, as health advisors say both Tdap and Td vaccines are acceptable for routin…
CDC Apr 4, 2026
Influenza and Tdap vaccination coverage among pregnant women in the United States
OB/GYN & Women's Health
Influenza and Tdap vaccination coverage among pregnant women in the United States Report examines flu and whooping cough vaccination rates in pregnant women
An observational report describes influenza and Tdap vaccination coverage among pregnant women in the United States.
A new report examines flu and whooping cough vaccination rates for pregnant women during the 2019-20 season, highlighting the need for more …
CDC Apr 4, 2026
New 6-in-1 infant vaccine licensed but availability delayed until at least 2021
Gastroenterology
New 6-in-1 infant vaccine licensed but availability delayed until at least 2021 New six-in-one vaccine for infants receives regulatory approval
A new combination vaccine for infants targeting diphtheria, tetanus, pertussis, polio, Hib, and hepatitis B has received licensure.
A new six-in-one vaccine for infants has received regulatory approval, but it won't be available for use until 2021 or later.
CDC Apr 3, 2026

Questions about Tetanus

How does the new infant vaccine protect against Tetanus compared to old ones?

The new 6-in-1 infant vaccine protects against tetanus just as well as older vaccines, but combines it with protection against five other diseases in one shot, reducing the number of injections.

Full answer →
Can pregnant women in the US get the Tdap vaccine to prevent Tetanus?

Yes, pregnant women in the US are recommended to get the Tdap vaccine to protect themselves and their babies from tetanus and whooping cough.

Full answer →