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Home › Conditions › tonsillectomy

Tonsillectomy

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for tonsillectomy

14 trials tracked for tonsillectomy: 5 in phase 3 or 4 and 2 with published results. The most-cited published study has 19 citations.

14Trials tracked
5Phase 3 & 4
0Recruiting
2With published results
Phase distribution
Phase 4 3 Phase 3 2 Phase 2 4 Other / NA 5
  1. Phase 4 Modified Pre-operative Oral Doses Acetaminophen Versus Intravenous Acetaminophen Completed · 19 cited
  2. Phase 4 Muscle Relaxation for Pediatric Adenotonsillectomy Completed
  3. Phase 4 EXPAREL® for Pain After Tonsillectomy Completed
  4. Phase 3 Safety and Efficacy of Intravenous Ibuprofen for Treatment of Pain in Pediatric Patients Undergoing Tonsillectomy Completed
  5. Phase 3 Dexmedetomidine as a Rapid Bolus in Children for Emergence Agitation Completed
  6. Phase 2 The Effect of Caffeine on Postextubation Adverse Respiratory Events in Children With Obstructive Sleep Apnea (OSA). Completed
Show 8 more trials
  1. Phase 2 Celecoxib After Tonsillectomy Completed
  2. Phase 2 Postoperative Ibuprofen and the Risk of Bleeding After Tonsillectomy With or Without Adenoidectomy Completed
  3. Phase 2 Psychological Influences on Postoperative Recovery Completed
  4. N/A Default Dosing Settings for Opioid Prescriptions to Adolescents and Young Adults After Tonsillectomy Completed
  5. N/A Adenotonsillectomy Postoperative Parental Teaching Tool Completed
  6. N/A A Study of BiZact™ on Adults Undergoing Tonsillectomy Completed
  7. N/A A Study of BiZact™ on Children and Adolescents Undergoing Tonsillectomy Completed
  8. N/A Use of Laryngeal Mask Airway in Pediatric Adenotonsillectomy Completed

Showing the 14 most-cited and recently-updated of 14 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Systematic review meta-analysis shows higher complication rates in young children undergoing tonsillectomy
Pediatrics Meta-analysis
Systematic review meta-analysis shows higher complication rates in young children undergoing tonsillectomy Young kids under three can safely go home after tonsil surgery
This systematic review and meta-analysis evaluated complications of tonsillectomy or adenotonsillectomy in children aged 2 to 3 years compar…
New research shows toddlers aged two to three can likely go home the same day after having their tonsils removed without extra risk.
May 1, 2026
Esketamine vs fentanyl for pediatric tonsillectomy pain shows comparable FLACC scores
Pediatrics RCT
Esketamine vs fentanyl for pediatric tonsillectomy pain shows comparable FLACC scores Esketamine and fentanyl ease kids' tonsil pain equally after surgery
This randomized controlled trial in 54 children scheduled for tonsillectomy compared esketamine 0.5 mg·kg to fentanyl 4 μg·kg at induction.
For kids getting tonsils out, esketamine and fentanyl control pain just as well, but esketamine keeps blood pressure steadier during surgery…
Apr 23, 2026