HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Diabetes & Endocrinology
Cohort
Retrospective cohort study assesses diagnostic accuracy for Wagner Grade ≥2 DFUs in hospitalized type 2 diabetes patients.
New Tool Predicts Severe Foot Ulcers in Diabetic Patients Before They Worsen
This retrospective cohort study evaluated diagnostic accuracy for Wagner Grade ≥2 diabetic foot ulcers (DFUs) in 510 hospitalized patients w…
This new calculator could help doctors spot dangerous foot ulcers in diabetic patients sooner, giving them a chance to act before it’s too l…
Frontiers
Apr 21, 2026
Diabetes & Endocrinology
Cohort
Untargeted LC-MS/MS profiling identifies metabolite networks associated with glycemic dysregulation in diabetes cohorts.
A new chemical link connects early diabetes risks to specific proteins in your blood.
This cohort study profiled 15,470 serum metabolite features in people with normal glucose tolerance, prediabetes, and type 2 diabetes. Coreg…
Scientists found a specific chemical pattern that grows stronger as diabetes gets worse, offering a fresh view on how the disease starts.
medRxiv
Apr 21, 2026
Diabetes & Endocrinology
Laboratory study examines SLC30A8 R138X variant effects on human stem cell-derived islet-like clusters.
How a Genetic Mutation Shields Pancreas Cells From Stress
This research article reports a laboratory study investigating the SLC30A8 R138X loss-of-function variant in human stem cell-derived islet-l…
A specific gene mutation acts as a natural shield, keeping insulin-producing cells alive when they face zinc stress that usually causes them…
medRxiv
Apr 21, 2026
Psychiatry
Review of new-user target trial emulation comparing semaglutide and SGLT2i in U.S. Veterans with type 2 diabetes
Semaglutide Does Not Raise Suicide Risk, Study Finds
This active-comparator, new-user target trial emulation review synthesizes data from 102,361 U.S. Veterans with type 2 diabetes comparing se…
A large new study finds that semaglutide does not increase suicide risk compared to other diabetes drugs, easing fears for millions of patie…
medRxiv
Apr 21, 2026
Diabetes & Endocrinology
Cohort
Young-onset type 2 diabetes and menopause status linked to all-cause mortality in Chinese women.
Diabetes at 40? This Number Could Save Your Life
This observational cohort study of 5984 Chinese women with type 2 diabetes found a lower all-cause mortality rate in young-onset versus late…
For postmenopausal women under 40 with diabetes, a specific marker predicts higher death risk than age alone, offering a vital early warning…
Frontiers
Apr 19, 2026
Diabetes & Endocrinology
Cohort
Retrospective cohort finds COVID-19 infection linked to proteinuria progression in type 2 diabetes
Does COVID-19 worsen kidney issues in people with diabetes?
A retrospective cohort study of 688 patients with type 2 diabetes and COVID-19 versus 502 pre-pandemic uninfected patients with type 2 diabe…
Type 2 diabetes patients fear COVID-19 could worsen kidney stress, raising questions about whether weight or obesity accelerates the risk.
Frontiers
Apr 19, 2026
Diabetes & Endocrinology
Monitoring report on US GLP-1 RA prescribing trends shows increased oral semaglutide use.
Why are so many people getting new diabetes and weight-loss drugs?
This monitoring report analyzes real-world US electronic health record data from Truveta on GLP-1 RA prescribing. It finds increased prescri…
Prescriptions for diabetes and weight-loss drugs jumped sharply in the US after a new oral pill was approved, with first-time use rising ove…
medRxiv
Apr 19, 2026
Neurology
Genetic analyses suggest causal links between type 2 diabetes markers and cerebral small vessel disease phenotypes
High Blood Sugar May Drive Small Stroke Risk
This review synthesizes genome-wide association and Mendelian randomization data linking type 2 diabetes and glycemic indicators to cerebral…
Managing blood sugar after meals might lower your risk of a specific type of stroke.
medRxiv
Apr 19, 2026
Genetics & Precision Medicine
Observational biobank study compares phenomic and social determinants for disease risk prediction
Your Genes Aren’t Your Destiny: How Your Neighborhood Changes Your Risk
This research article from UK Biobank and other cohorts evaluates phenome-derived polygenic scores and social determinants for predicting as…
Your neighborhood and lifestyle can reshape your genetic risk for diseases like asthma and heart disease, offering a clearer health picture …
medRxiv
Apr 19, 2026
Diabetes & Endocrinology
Cohort
Inflammatory and metabolic indices associated with microvascular complications in hospitalized type 2 diabetes patients.
Two Blood Markers Could Predict Serious Diabetes Complications Years Earlier
This retrospective cohort study examined 964 hospitalized patients with type 2 diabetes to assess associations between inflammatory and meta…
Two blood scores measuring inflammation and metabolic stress may predict serious diabetes complications years before symptoms appear.
Frontiers
Apr 18, 2026
Diabetes & Endocrinology
Cohort
Three-parameter online nomogram predicts diabetic retinopathy risk in community-dwelling type 2 diabetes patients.
Three Numbers Could Tell Your Doctor If Your Eyes Are at Risk
This retrospective cohort study evaluated a three-parameter online nomogram using diabetes duration, HbA1c, and high BMI (≥24 kg/m²) to pred…
A free, web-based calculator using only your diabetes duration, blood sugar control, and BMI could help doctors spot who needs an urgent eye…
Frontiers
Apr 18, 2026
Drug Pipeline
RCT
Mazdutide monotherapy reduces HbA1c and promotes weight loss in Chinese adults with type 2 diabetes over 48 weeks.
New Drug Lowers Sugar and Shrinks Weight in Diabetes
This phase 3 randomized controlled trial evaluated weekly subcutaneous mazdutide (4 mg or 6 mg) versus placebo in Chinese adults with type 2…
A new diabetes drug called mazdutide lowers blood sugar and shrinks weight in adults who struggle with diet and exercise alone.
Nat Med
Apr 16, 2026