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Home › Conditions › Wilms tumor

Wilms tumor

Part of Urologic Neoplasms

4 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Wilms tumor

7 trials tracked for Wilms tumor.

7Trials tracked
0Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 2 6 Other / NA 1
  1. Phase 2 Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial) Completed
  2. Phase 2 Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial) Completed
  3. Phase 2 Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial) Completed
  4. Phase 2 Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial) Completed
  5. Phase 2 Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial Sarcoma Completed
  6. Phase 2 Study of High-Dose Chemotherapy With Bone Marrow or Stem Cell Transplant for Rare Poor-Prognosis Cancers Completed
Show 1 more trials
  1. N/A Molecular-Guided Therapy for Childhood Cancer Completed

Showing the 7 most-cited and recently-updated of 7 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Case review of epithelial-type Wilms tumor in a 23-year-old female with clear surgical margins
Oncology Sys. Review
Case review of epithelial-type Wilms tumor in a 23-year-old female with clear surgical margins A rare kidney tumor in a young adult was removed with clear margins and no spread
This case review describes a 23-year-old female who underwent right radical nephrectomy for a rare epithelial-type Wilms tumor. Histopatholo…
A 23-year-old woman had a rare kidney tumor removed. The surgery showed clear edges and no spread. This case highlights the need for awarene…
Frontiers May 17, 2026
UK trial reports 4-year event-free survival of 63% and overall survival of 68% in relapsed Wilms tumour patients
Pediatrics
UK trial reports 4-year event-free survival of 63% and overall survival of 68% in relapsed Wilms tumour patients High-dose chemo plus stem cell rescue offers hope for relapsed Wilms tumour
This clinical trial report evaluates outcomes for 78 children with relapsed or refractory Wilms tumour treated in the United Kingdom.
A UK trial found that a risk-stratified protocol with high-dose melphalan and stem cell rescue helped some children with relapsed Wilms tumo…
May 1, 2026
Case report and literature review on mosaic DICER1 mutations and disease stability in a 6-month-old boy
Pediatrics Sys. Review
Case report and literature review on mosaic DICER1 mutations and disease stability in a 6-month-old boy One Baby, Five Tumors, One Tiny Gene Change
This case report and literature review describes a 6-month-old boy with mosaic DICER1 RNase IIIb hotspot mutation and multiple tumors.
A 6-month-old boy developed five different tumors linked to one small gene change, showing how one mutation can drive multiple childhood can…
Frontiers Apr 28, 2026
Late Wilms tumor recurrence observed 32 years after diagnosis in a single case report
Oncology Sys. Review
Late Wilms tumor recurrence observed 32 years after diagnosis in a single case report A Childhood Kidney Tumor Returned 32 Years Later
This systematic review analyzed a case report of a one-year-old female with bilateral, favorable-histology Wilms tumor.
Very late recurrence of childhood kidney cancer is extremely rare but possible, and this case reminds survivors and doctors that long-ago ca…
Frontiers Apr 13, 2026

Research across Urologic Neoplasms

Related studies from across the Urologic Neoplasms family.

Case report of 3-year-old girl with bilateral Wilms tumor and TP53 mutation treated with VAD chemotherapy and surgery
Pulmonology & Critical Care Sys. Review
Case report of 3-year-old girl with bilateral Wilms tumor and TP53 mutation treated with VAD chemotherapy and surgery 3-year-old girl with TP53 mutation and bilateral Wilms tumor died after treatment
This case-based review describes a single 3-year-old girl with bilateral Wilms tumor and a TP53 mutation treated under the Chinese Children …
A single case report describes a 3-year-old girl with bilateral Wilms tumor and a TP53 mutation who died despite aggressive chemotherapy and…
Frontiers May 22, 2026

Questions about Wilms tumor

Can an epithelial-type Wilms tumor be treated with surgery?

Surgery is a standard treatment for epithelial-type Wilms tumor in both children and adults.

Full answer →
What are the outcomes for patients with relapsed Wilms tumor in the UK?

A UK trial for relapsed Wilms tumor reported a 63% four-year event-free survival rate and a 68% overall survival rate.

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Can a Wilms tumor return many years after the initial diagnosis?

While rare, Wilms tumor can recur many years after the initial diagnosis, with one documented case occurring 32 years after the first diagnosis.

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Can a Wilms tumor occur in an adult woman?

While Wilms tumor is primarily a childhood cancer, it can occur in adult women, though these cases are extremely rare.

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