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Home › Medications › gabapentin

gabapentin

3 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of gabapentin

75 trials tracked of gabapentin: 40 in phase 3 or 4 and 15 with published results. The most-cited published study has 167 citations.

75Trials tracked
40Phase 3 & 4
0Recruiting
15With published results
Phase distribution
Phase 4 23 Phase 3 17 Phase 2 17 Phase 1 3 Other / NA 15
  1. Phase 3 Clinical Trial of Gabapentin to Decrease Postoperative Delirium and Pain Completed · 167 cited
  2. Phase 4 MAST Trial: Multi-modal Analgesic Strategies in Trauma Completed · 51 cited
  3. Phase 4 Gabapentin vs Chlordiazepoxide for Ambulatory Alcohol Withdrawal Completed · 46 cited
  4. Phase 4 Perioperative Gabapentin Use In Head And Neck Mucosal Surgery Patients Completed · 30 cited
  5. Phase 4 Gabapentin for Headache in Aneurysmal Subarachnoid Hemorrhage Completed · 20 cited
  6. Phase 3 Gabapentin for the Reduction of Radiation Therapy Induced Pain During the Treatment of Oropharyngeal Cancer Completed · 20 cited
Show 44 more trials
  1. Phase 3 Gabapentin for Abstinence Initiation in Alcohol Dependence Completed · 18 cited
  2. Phase 4 Single Dose Preoperative Gabapentin Use in Minimally Invasive Hysterectomy for Acute Pain Management Completed · 11 cited
  3. Phase 4 Simulated Driving Performance, Daytime Sedation and Cognition in Healthy Volunteers Taking Gralise, Neurontin or Lyrica Completed · 8 cited
  4. Phase 4 Gabapentin as an Adjunct to Paracervical Block for Perioperative Pain Management Completed · 7 cited
  5. Phase 3 Gabapentin for Post-Operative Pain Control and Narcotic Reduction in Scrotal Surgery Completed · 6 cited
  6. Phase 4 Prevention of Persistent Opioid Use in Mothers Completed · 5 cited
  7. Phase 4 Gabapentin for Postop Pain After SSLF Completed · 4 cited
  8. Phase 4 Gabapentin for Alcohol Withdrawal Syndrome Completed · 4 cited
  9. Phase 3 Improving Treatment Outcomes for Prescription Opioid Dependence Completed · 1 cited
  10. Phase 4 Pain Control With Total Knee Replacement Completed
  11. Phase 4 Early Diuresis Following Colorectal Surgery Completed
  12. Phase 4 Administration of Pre-Operative Gabapentin to Patients Undergoing Laparoscopy Completed
  13. Phase 4 Pain Expectations in Subjects With Osteoarthritis Completed
  14. Phase 4 Opioid-Free Shoulder Arthroplasty Completed
  15. Phase 4 Gabapentin Regimens and Their Effects on Opioid Consumption Completed
  16. Phase 4 Evaluation of Initiation Time on the Efficacy of Gabapentin in Treating Neuropathic Pain in SCI Completed
  17. Phase 4 Efficacy of Opioid-limiting Pain Management Protocol in Men Undergoing Urethroplasty Completed
  18. Phase 4 Preoperative Gabapentin vs Placebo for Vaginal Prolapse Surgery Completed
  19. Phase 4 Nonopioid Pain Control Regimen After Arthroscopic Hip Procedures Completed
  20. Phase 4 A Study to Compare Safety and Efficacy of Tramadol Hydrochloride/Acetaminophen With Gabapentin in Participants With Diabetic Neuropathy Completed
  21. Phase 4 An Open-Label Comparison of Duloxetine to Other Alternatives for the Management of Diabetic Peripheral Neuropathic Pain Completed
  22. Phase 4 Comparative Study Of Pregabalin And Gabapentin As Adjunctive Therapy In Subjects With Partial Seizures Completed
  23. Phase 3 Novel Topical Therapies for the Treatment of Genital Pain Completed
  24. Phase 3 Gabapentin in Reducing the Need for Pain Medication in Patients With Bladder Cancer Undergoing Radical Cystectomy Completed
  25. Phase 3 Gabapentin Compared to Standard of Care in Preventing Mucositis in Patients With Stage III-IV Head and Neck Cancer Undergoing Primary or Adjuvant Chemoradiation Therapy Completed
  26. Phase 3 Next-Day Residual Effects of Gabapentin, Diphenhydramine and Triazolam on Simulated Driving Performance in Normal Volunteers Completed
  27. Phase 3 Multimodal Pain Management After Robotic-Assisted Total Laparoscopic Hysterectomy Completed
  28. Phase 3 Nonopioid Analgesia After Anterior Cruciate Ligament Reconstruction Completed
  29. Phase 3 Neuropathic Pain Management Completed
  30. Phase 3 Gabapentin in Preventing Nausea and Vomiting in Patients Receiving Chemotherapy Completed
  31. Phase 3 Gabapentin in the Prevention of Nausea and Vomiting Induced by Chemotherapy Completed
  32. Phase 3 A Phase III Open-Label Study Of Gabapentin As Adjunctive Therapy In Japanese Pediatric Patients With Partial Seizures Completed
  33. Phase 3 Pilot Study Comparing Hypnotherapy and Gabapentin for Hot Flashes. Completed
  34. Phase 3 A Phase III Open-Label Extension Study Of Gabapentin As Adjunctive Therapy In Japanese Pediatric Patients With Partial Seizures Completed
  35. Phase 2 Hyperalgesia in Methadone-Maintained Patients: Can it be Treated? Completed
  36. Phase 2 St. PETERsburg Pain and Alcohol Intervention With Naltrexone and Gabapentin Completed
  37. Phase 2 Gabapentin Treatment of Benzodiazepine Abuse in Methadone Maintenance Patients Completed
  38. Phase 2 Gabapentin, Methadone, and Oxycodone With or Without Venlafaxine Hydrochloride in Managing Pain in Participants With Stage II-IV Squamous Cell Head and Neck Cancer Undergoing Chemoradiation Therapy Completed
  39. Phase 2 Gabapentin for Alcohol Relapse Prevention Completed
  40. Phase 2 Gabapentin as an Adjunct to Perioperative Pain Management Regimens for Uterine Aspiration Completed
  41. Phase 2 Gabapentin for Bipolar & Cannabis Use Disorders Completed
  42. Phase 2 Gabapentin Treatment of Cannabis Dependence Completed
  43. Phase 2 PECS Block vs. Multimodal Analgesia for Prevention of Persistent Postoperative Pain in Breast Surgery Completed
  44. Phase 2 Medication Development for Opioid and Alcohol Abuse Completed

Showing the 50 most-cited and recently-updated of 75 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Meta-analysis shows preoperative COX-2 inhibitors and gabapentin reduce opioid use after arthroscopic surgery
Anesthesiology & Pain Medicine Meta-analysis
Meta-analysis shows preoperative COX-2 inhibitors and gabapentin reduce opioid use after arthroscopic surgery Surgery Patients Cut Opioid Use With Smart Pre-Operation Pain Plan
This systematic review and meta-analysis evaluated 22 studies involving patients undergoing arthroscopic surgery. Preoperative treatment wit…
• Pre-surgery non-opioid pills reduce opioid needs after joint surgery • Helps knee and shoulder surgery patients avoid extra pills • Small …
May 6, 2026
Retrospective cross-sectional study characterizes arachnoiditis patient presentation and treatment responses in 1105 participants
Neurology
Retrospective cross-sectional study characterizes arachnoiditis patient presentation and treatment responses in 1105 participants Back Pain That Won't Go Away
This retrospective cross-sectional study characterized clinical presentation, comorbidities, and treatments in 1105 participants with physic…
A massive online community of chronic pain patients helped researchers finally map the symptoms and treatments for the often missed conditio…
medRxiv Apr 15, 2026
FDA Approves Gabapentin Capsules (gabapentin) for Postherpetic Neuralgia and Partial Onset Seizures
Neurology FDA Approval
FDA Approves Gabapentin Capsules (gabapentin) for Postherpetic Neuralgia and Partial Onset Seizures FDA approves a new generic version of the drug gabapentin for nerve pain and seizures
The FDA has approved Gabapentin Capsules, USP for the management of postherpetic neuralgia in adults and as adjunctive therapy for partial o…
FDA approves a new generic gabapentin capsule for nerve pain and seizures, offering patients another low-cost treatment option alongside exi…
FDA Apr 9, 2026