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Genetics & Precision Medicine
Case-Control
Rare CNV dosage associated with Alzheimer's disease risk in exome case-control study
Rare DNA Errors Found Linked to Higher Alzheimer's Risk
This case-control study analyzed exome data from individuals with Alzheimer's disease and controls. It found that 22q11.21 duplication carri…
Scientists found specific DNA changes that may make some people more likely to develop Alzheimer's.
medRxiv
Apr 23, 2026
Radiology & Imaging
Cohort
Symmetry-informed inverse learning model evaluated for metastasis and Alzheimer disease detection on healthy brain MRI slices.
Normal Scans Reveal Hidden Brain Problems
This cohort study evaluated a symmetry-informed inverse learning foundation model using healthy brain MRI slices and external lesion dataset…
New brain scan analysis spots hidden problems by studying only healthy images, catching subtle issues that standard sick-brain training miss…
medRxiv
Apr 16, 2026
Neurology
RCT
Brain reserve moderates AD pathology associations with cognitive function in cognitively unimpaired adults
Younger Brains Shield Memory From Early Alzheimer's
This cross-sectional analysis of baseline data from a multisite randomized clinical trial examined 621 cognitively unimpaired, physically in…
Your brain's "fitness level" can act like a shield, protecting your memory even when early Alzheimer's proteins are present.
Apr 15, 2026
Genetics & Precision Medicine
Cohort
Genetic correlation between kidney function and Alzheimer disease is absent in European and African ancestry cohorts.
Why Kidneys and the Aging Brain May Share More DNA Than We Knew
This cohort study examined shared genetic architecture between kidney function and Alzheimer disease in European and African ancestry indivi…
Kidney disease patients face higher Alzheimer's risk because specific genes link the two conditions, with the famous APOE gene playing a key…
medRxiv
Apr 10, 2026