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Bacterial pneumonia

Part of Pneumonia

3 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for bacterial pneumonia

21 trials tracked for bacterial pneumonia: 11 in phase 3 or 4 and 3 with published results. The most-cited published study has 229 citations.

21Trials tracked
11Phase 3 & 4
0Recruiting
3With published results
Phase distribution
Phase 4 1 Phase 3 10 Phase 2 7 Other / NA 3
  1. Phase 3 Omadacycline vs Moxifloxacin for the Treatment of CABP (EudraCT #2013-004071-13) Completed · 229 cited
  2. Phase 3 Imipenem/Relebactam/Cilastatin Versus Piperacillin/Tazobactam for Treatment of Participants With Bacterial Pneumonia (MK-7655A-014) Completed · 223 cited
  3. Phase 3 Inhaled Amikacin Solution BAY41-6551 as Adjunctive Therapy in the Treatment of Gram-Negative Pneumonia Completed · 131 cited
  4. Phase 4 Pharmacodynamic of Ceftaroline and Levofloxacin Against Pathogens Associated With Community Acquired Bacterial Pneumonia Completed
  5. Phase 3 Efficacy and Safety of Nemonoxacin vs Levofloxacin in Adult Patients With Community-Acquired Pneumonia Completed
  6. Phase 3 Omadacycline vs. Moxifloxacin for the Treatment of Community-Acquired Bacterial Pneumonia Completed
Show 15 more trials
  1. Phase 3 Comparison of Telavancin and Vancomycin for Hospital-acquired Pneumonia Due to Methicillin-resistant Staphylococcus Aureus Completed
  2. Phase 3 The Study of Unasyn-S 12g/Day for Community Acquired Pneumonia (CAP) Completed
  3. Phase 3 Comparative Study of Ceftaroline vs. Ceftriaxone in Adults With Community-Acquired Pneumonia Completed
  4. Phase 3 Comparison of Telavancin and Vancomycin for Hospital-acquired Pneumonia Due to Methicillin-resistant Staphylococcus Aureus Completed
  5. Phase 3 Comparative Study of Ceftaroline vs. Ceftriaxone in Adult Subjects With Community-Acquired Pneumonia Completed
  6. Phase 2 A Study Of Intravenous Sulopenem And Oral PF-03709270 In Community Acquired Pneumonia That Requires Hospitalization Completed
  7. Phase 2 An Effectiveness, Safety, and Microbiology Study of Doripenem in Patients With Nosocomial (Hospital-acquired) Pneumonia Completed
  8. Phase 2 A Single Ascending Dose Study in Adults (Stage 1) and Single Ascending Dose-Finding Study (Stage 2) in Elderly Subjects With ASP3772, A Pneumococcal Vaccine Completed
  9. Phase 2 A Safety and Tolerability Study of Doripenem in Patients With Abdominal Infections or Pneumonia Completed
  10. Phase 2 Study Evaluating the Pharmacokinetics (PK), Safety, and Tolerability of Tigecycline in Patients 8 to 11 Years of Age Completed
  11. Phase 2 Cx611-0204 SEPCELL Study Completed
  12. Phase 2 Aerosolized Amikacin and Fosfomycin in Mechanically Ventilated Patients With Gram-negative Pneumonia Completed
  13. N/A Vaccination Education Through Pharmacists and Senior Centers (VEPSC) Completed
  14. N/A Urease Breath Test for Rapid Characterization of Pneumonia Completed
  15. N/A PROcalcitonin Impact on Antibiotic Reduction, adverSe Events and AVoidable healthcarE Costs (ProSAVE): A RCT Completed

Showing the 21 most-cited and recently-updated of 21 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Pneumonia

Related studies from across the Pneumonia family.

Inhaled antibiotics improve clinical cure and reduce mortality in ventilator-associated pneumonia
Infectious Disease Meta-analysis
Inhaled antibiotics improve clinical cure and reduce mortality in ventilator-associated pneumonia Inhaled antibiotics help cure pneumonia and lower death risk in ICU patients
This systematic review and meta-analysis of adjunctive inhaled antibiotics for ventilator-associated pneumonia found significantly improved …
Adding inhaled antibiotics to standard care improved cure rates and reduced death in patients with ventilator-associated pneumonia.
NIV with total face mask managed acute respiratory failure in two patients with Madelung's disease and COVID-19 pneumonia
Rheumatology Sys. Review
NIV with total face mask managed acute respiratory failure in two patients with Madelung's disease and COVID-19 pneumonia Non-invasive ventilation may help patients with Madelung's disease and respiratory failure
This case series describes non-invasive ventilation using a total face mask in two patients with Madelung's disease who experienced acute re…
A small case series suggests non-invasive ventilation can manage acute respiratory failure in patients with Madelung's disease, though more …
Systemic corticosteroid therapy significantly decreased length of hospital stay and fever duration in children with community-acquired pneumonia
Infectious Disease Meta-analysis
Systemic corticosteroid therapy significantly decreased length of hospital stay and fever duration in children with community-acquired pneumonia Shorter hospital stays and fever for kids with pneumonia using steroids
This systematic review and meta-analysis evaluated systemic corticosteroid therapy versus controls in children with community-acquired pneum…
A large review found that adding steroids to standard antibiotics helped children with pneumonia leave the hospital faster and get over thei…
High mortality rates observed in community-acquired pneumonia patients within intensive care units across low- and middle-income regions
Emergency Medicine Meta-analysis
High mortality rates observed in community-acquired pneumonia patients within intensive care units across low- and middle-income regions Community-acquired pneumonia kills one in three ICU patients in low- and middle-income countries
A systematic review and meta-analysis of 48,707 patients reveals stark mortality risks for community-acquired pneumonia in resource-limited …
A massive review shows that one in three patients with pneumonia admitted to ICUs in low- and middle-income countries dies within a month.
Systematic review maps 50 most-cited articles on pediatric respiratory infections
Pediatrics Sys. Review
Systematic review maps 50 most-cited articles on pediatric respiratory infections Most cited research on child respiratory infections comes from US, China, Canada
This systematic bibliometric review analyzed the 50 most-cited articles on pediatric respiratory infections. Key findings show a predominanc…
A review of 50 top-cited articles on pediatric respiratory infections shows most research comes from just three countries.
TCM injections plus conventional medicine show promise for viral pneumonia
Drug Pipeline Meta-analysis
TCM injections plus conventional medicine show promise for viral pneumonia Seven Chinese Medicine Injections Compared for Viral Pneumonia Recovery
A network meta-analysis of 8,678 patients found that specific TCM injections combined with conventional medicine improved outcomes like coug…
A large review of 8,678 patients found that adding a Chinese medicine injection called Reduning to standard care may help people with viral …
Systematic review and meta-analysis of pneumonia prevalence and antimicrobial resistance in Ghana
Infectious Disease Meta-analysis
Systematic review and meta-analysis of pneumonia prevalence and antimicrobial resistance in Ghana Ghana's pneumonia rate hits 22 percent with one region most at risk
This systematic review and meta-analysis synthesizes data on pneumonia prevalence and antimicrobial resistance patterns among participants i…
A new review finds 22 percent of Ghanaians have pneumonia, with children under 5 especially vulnerable and widespread resistance to common a…
Meta-analysis finds no clear difference between amoxicillin and other antibiotics for community-acquired pneumonia
Pediatrics Meta-analysis
Meta-analysis finds no clear difference between amoxicillin and other antibiotics for community-acquired pneumonia Doctors find amoxicillin works just as well as other drugs for pneumonia
A systematic review and meta-analysis compared amoxicillin and amoxicillin-clavulanate to other antibiotics for community-acquired pneumonia…
New research shows a common antibiotic called amoxicillin works just as well as other options for treating pneumonia in people of all ages.
Evidence-based review of transducer selection for lung ultrasound in dogs and cats with pulmonary pathology
Pulmonology & Critical Care Sys. Review
Evidence-based review of transducer selection for lung ultrasound in dogs and cats with pulmonary pathology Choosing the right ultrasound probe can improve lung diagnoses for dogs and cats
This evidence-based review examines transducer selection for lung ultrasound in dogs and cats with pulmonary pathology.
Veterinary lung ultrasound accuracy depends on probe choice. This review highlights how transducer selection affects diagnosis in emergency …
Meta-analysis shows integrated nursing interventions improve outcomes in paediatric severe pneumonia
Pediatrics Meta-analysis
Meta-analysis shows integrated nursing interventions improve outcomes in paediatric severe pneumonia Integrated nursing care improves severe pneumonia in children
This meta-analysis reviews six studies conducted in paediatric intensive care units involving paediatric patients with severe pneumonia.
A review of six studies finds that integrated nursing care helps children with severe pneumonia recover faster, with less fever and shorter …
Hospitalized children with HMPV infection had 28.0% severe CAP rates and higher risks of wheezing and co-infection
Emergency Medicine Cohort
Hospitalized children with HMPV infection had 28.0% severe CAP rates and higher risks of wheezing and co-infection Premature birth and wheezing raise severe HMPV pneumonia risk
This retrospective cohort study examined 878 hospitalized children with human metapneumovirus (HMPV)-positive community-acquired pneumonia (…
A study of 878 children finds premature birth and wheezing are strong predictors of severe HMPV pneumonia.
Azithromycin to doxycycline switching in children with Mycoplasma pneumoniae pneumonia resistance gene positivity
Pediatrics Cohort
Azithromycin to doxycycline switching in children with Mycoplasma pneumoniae pneumonia resistance gene positivity Testing for resistance genes may guide antibiotic choices
This retrospective cohort study of 150 children with Mycoplasma pneumoniae pneumonia evaluated resistance gene expression and antibiotic man…
New evidence suggests that checking for resistance genes in children with pneumonia could help doctors decide when to switch antibiotics.