Adrenergic receptor signaling modulates pulmonary innate immunity and barrier integrity in acute lung injury
Understanding How Nerve Signals Influence Lung Health During Severe Respiratory Infections
This systematic review synthesizes the role of adrenergic receptors (ARs) as a molecular interface between the sympathetic nervous system an…
New research explores how specific nerve signals help control inflammation and protect the lungs during severe lung infections.
Shorter antibiotic courses may match longer ones for canine pneumonia, but evidence is weak
Shorter antibiotic courses work just as well as longer ones for dog pneumonia
This systematic review and meta-analysis of 74 dogs found no significant difference in treatment success between shorter (10-14 days) and lo…
A new analysis suggests shorter antibiotic courses may treat dog pneumonia just as well as longer ones, though evidence for cats is missing.
EBOV-specific gene signature identified in nonhuman primates and human cohorts with Ebola infection
New gene signature can spot Ebola infection in blood samples
This observational cohort study analyzed RNA-Seq data from nonhuman primates and human cohorts with Ebola virus infection and comparator inf…
Researchers found a 50-gene signature that reliably separates Ebola from other infections in blood tests, pointing to a future diagnostic to…
Mechanistic review discusses host-directed therapy for children with Long COVID and secondary bacterial pneumonia
Could monitoring specific blood markers help prevent long-term lung damage in kids with Long COVID?
This mechanistic review addresses Long COVID, Post-Acute Sequelae of SARS-CoV-2 infection, and secondary bacterial pneumonia in children.
Monitoring blood markers like ferritin and D-dimer could help doctors catch dangerous lung inflammation early in kids with Long COVID before…
Research across Pneumonia
Related studies from across the Pneumonia family.
Protocol for comparing azithromycin and doxycycline with beta-lactams in community-acquired pneumonia
New trial to test azithromycin vs doxycycline for pneumonia
This is a protocol for a planned randomized clinical trial involving 1120 adult patients hospitalized with community-acquired pneumonia. No …
A large trial will compare two antibiotic combos for hospitalized pneumonia patients. Which works better?
AI models provide high accuracy for pulmonary inflammation and COVID-19 detection in diverse populations
Artificial Intelligence Shows Promise for Detecting Lung Inflammation
This mini-review synthesizes evidence on artificial intelligence applications for detecting pulmonary inflammation and managing perioperativ…
New research shows that artificial intelligence tools can accurately identify lung conditions like pneumonia and COVID-19 from medical imagi…
Airway clearance techniques triple odds of treatment success in Chinese pneumonia patients
Airway clearance techniques may improve treatment for pneumonia patients
This meta-analysis of RCTs in Chinese adults with pneumonia found that adding airway clearance techniques to conventional treatment signific…
Adding airway clearance to standard care may help Chinese adults with pneumonia breathe better and face fewer complications.
Short-course antibiotic therapy yields comparable clinical and bacteriological success for adults with community-acquired pneumonia
Shorter antibiotics work just as well for pneumonia
This meta-analysis of 21 RCTs found that short-course antibiotic therapy (≤5 days) provides comparable clinical, bacteriological, and radiol…
For adults with pneumonia, 5 days or less of antibiotics works as well as longer courses, with fewer severe side effects.
AI diagnostic tools show high accuracy but limited real-world validation in systematic review
Artificial intelligence shows high accuracy in detecting various medical conditions
This systematic review of 24 studies synthesizes evidence on AI and deep learning for disease detection across multiple imaging modalities. …
New analysis of 24 studies shows AI tools can reach over 90% accuracy in spotting everything from lung cancer to skin disorders.
CD4+ T cells and Tim-3 regulate immune responses and cytokine-mediated injury in severe pediatric pneumonia
Immune system hurdles shape severity of severe childhood pneumonia
This narrative review examines how CD4+ T cells, Tim-3 (HAVCR2), and cytokines influence the host immune response in severe pneumonia. The a…
New research explores how specific immune cells and proteins may drive the intense inflammation seen in children with severe pneumonia.
Brain-Lung-Immune-Microbiome Axis replaces biomechanical models in understanding ventilator-associated pneumonia after traumatic brain injury
New Framework Explains Lung Infections After Brain Injuries
This narrative review explores the transition from a traditional biomechanical model of ventilator-associated pneumonia to a multidimensiona…
A new model suggests that brain injuries create a complex immune and microbiome response that leads to lung infections in intensive care pat…
Colistin-based inhalation regimens rank highest for clinical response in multidrug-resistant Acinetobacter baumannii pneumonia
Colistin Inhalation Tops for Drug-Resistant Pneumonia
This network meta-analysis of 1420 patients with multidrug-resistant Acinetobacter baumannii (MDRAB) pneumonia compared colistin, tigecyclin…
For tough pneumonia, inhaled colistin works best, but sulbactam is a good alternative without the toxicity.
Nebulised Chinese herbal medicine as adjunctive therapy improves clinical effective rate in pediatric pneumonia
Chinese Herbal Medicine Boosts Pneumonia Treatment in Children
This meta-analysis of randomized controlled trials evaluated nebulised Chinese herbal medicine as an adjunctive therapy for pediatric pneumo…
Adding nebulised Chinese herbal medicine to standard care improved pneumonia recovery in children, a meta-analysis of 1,764 patients found.
No risk score outperformed WHO IMCI criteria for predicting pediatric pneumonia mortality
Risk Scores Do Not Outperform Standard Care for Pneumonia
This secondary analysis of a randomized controlled trial evaluated five risk scores in 1010 children with pneumonia across five African coun…
New analysis shows standard clinical tools are just as effective as complex risk scores for predicting pneumonia outcomes in children.
Evaluating the Impact of Rapid Diagnostic Panels on Pediatric Pneumonia Management
New Testing Panel May Help Target Antibiotics for Child Pneumonia
A randomized trial explores how rapid diagnostic panels influence antibiotic adjustments and de-escalation for children with pneumonia.
A new testing panel may help doctors more accurately target antibiotics and reduce unnecessary medications for children with pneumonia.
Inhaled antibiotics improve clinical cure and reduce mortality in ventilator-associated pneumonia
Inhaled antibiotics help cure pneumonia and lower death risk in ICU patients
This systematic review and meta-analysis of adjunctive inhaled antibiotics for ventilator-associated pneumonia found significantly improved …
Adding inhaled antibiotics to standard care improved cure rates and reduced death in patients with ventilator-associated pneumonia.