HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Cardiology
Meta-analysis
Coexisting COPD and Atrial Fibrillation are associated with increased risk of mortality and bidirectional disease association
Patients with both lung and heart conditions face higher risks
This meta-analysis of 48 publications identifies a significant bidirectional risk between Chronic Obstructive Pulmonary Disease (COPD) and A…
People living with both chronic lung disease and irregular heartbeats face significantly higher risks for mortality.
Frontiers
Jun 19, 2026
Cardiology
RCT
Evaluating the Efficacy of Oral Digoxin in Patients with Rheumatic Heart Disease
Trial shows digoxin reduces heart failure risk in rheumatic heart disease
A large multicenter trial shows oral digoxin significantly reduces the risk of heart failure and death in patients with rheumatic heart dise…
A large clinical trial suggests that the medication digoxin may lower the risk of worsening heart failure for patients with rheumatic heart …
JAMA
Jun 16, 2026
Cardiology
Sys. Review
SGLT2 inhibitors provide robust prognostic benefits in heart failure with inconsistent results in post-myocardial infarction settings
SGLT2 inhibitors show promise for heart failure and diabetes
This narrative review examines the cardiovascular and metabolic effects of SGLT2 inhibitors, specifically empagliflozin and dapagliflozin. T…
New evidence shows how SGLT2 inhibitors may protect the heart and manage risks for patients with type 2 diabetes and heart failure.
Frontiers
Jun 9, 2026
Cardiology
Meta-analysis
Incidental arrhythmia findings on ambulatory ECG vary widely in adults without prior atrial fibrillation
Hidden heart rhythm problems found in up to 96% of adults
This systematic review and meta-analysis of 136,344 community-based adults without prior atrial fibrillation found that the prevalence of in…
A review of 136,344 adults found hidden heart rhythm issues in up to 96% of people without known atrial fibrillation.
Jun 5, 2026
Cardiology
Meta-analysis
Renal denervation combined with pulmonary vein isolation increases freedom from atrial fibrillation risk in resistant hypertension patients
Renal denervation may help resistant hypertension patients with heart issues
This systematic review and meta-analysis evaluated renal denervation in patients with resistant hypertension. The pooled analysis included 8…
A meta-analysis suggests renal denervation improves heart and sleep markers in patients with resistant hypertension, though larger trials ar…
Jun 2, 2026
Cardiology
Meta-analysis
Hypertension history associates with 2.22-fold higher cognitive impairment risk in AF patients
High blood pressure history doubles dementia risk in atrial fibrillation patients
This systematic review and meta-analysis of observational studies found that a history of hypertension is associated with an increased risk …
A history of high blood pressure is linked to a much higher risk of cognitive impairment in people with atrial fibrillation, according to a …
Frontiers
Jun 2, 2026
Cardiology
Meta-analysis
Left atrial appendage occlusion and NOACs reduce mortality compared with warfarin in atrial fibrillation
LAAO, low-dose NOACs beat warfarin for atrial fibrillation survival
A network meta-analysis compared left atrial appendage occlusion (LAAO), low-dose NOACs, standard-dose NOACs, and warfarin in non-valvular a…
For people with atrial fibrillation, warfarin may be the worst option for survival. New analysis finds LAAO and NOACs outperform it.
Jun 1, 2026
Cardiology
Meta-analysis
Pulsed-field ablation shows no significant AKI difference versus radiofrequency ablation in AF
Pulsed-field ablation shows similar kidney risk as radiofrequency ablation
This systematic review and meta-analysis of 3,843 patients found no significant difference in acute kidney injury (AKI) between pulsed-field…
A large review found no major difference in kidney injury risk between two heart rhythm treatments, though one method showed slightly higher…
Jun 1, 2026
Cardiology
Meta-analysis
Combined EPA and DHA supplementation showed no broad benefit for major adverse cardiovascular events in patients with established disease
New research shows combined fish oil supplements did not lower heart attack risk for patients with existing heart disease
This meta-analysis evaluated combined eicosapentaenoic acid and docosahexaenoic acid supplementation in patients with established cardiovasc…
A large study of over 25,000 patients found that taking moderate doses of EPA and DHA together did not significantly reduce major heart even…
Jun 1, 2026
Cardiology
Meta-analysis
Discontinuing oral anticoagulation after AF ablation reduces bleeding without increasing thromboembolic risk
Stopping blood thinners after heart rhythm repair cuts bleeding risk without raising stroke danger
This systematic review and meta-analysis evaluated patients who stopped versus continued oral anticoagulation following atrial fibrillation …
A massive analysis shows stopping blood thinners after heart rhythm repair cuts bleeding risk without raising stroke danger for many patient…
Jun 1, 2026
Cardiology
Guideline
Genetic testing utility is highest for syndromic supraventricular tachycardia where diagnosis alters prognosis and surveillance
Genetic testing clarifies some heart rhythm issues but is not routine for most cases
This narrative review and guideline addresses the genetic architecture of supraventricular tachycardia subtypes. The authors note that routi…
A review of genetic links to supraventricular tachycardia shows clear utility for syndromic cases, while routine testing remains limited for…
Frontiers
May 29, 2026
Psychiatry
Sys. Review
Narrative review on atrial fibrillation and depression highlights bidirectional links and integrated care needs
Depression and heart rhythm problems may worsen each other
This narrative review synthesizes evidence on the bidirectional relationship between atrial fibrillation and depression. It suggests depress…
A new review suggests depression and atrial fibrillation can fuel each other, making it vital to screen for both conditions together.
Frontiers
May 28, 2026