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Cardiology
RCT
Indirect comparison suggests Sphere-9 PFA catheter may have higher efficacy than Farawave for persistent AF
Two pulsed field ablation systems compared indirectly for persistent atrial fibrillation
A matched-adjusted indirect comparison of two pulsed field ablation (PFA) systems for symptomatic persistent atrial fibrillation found the S…
Patients treated with the Sphere-9 pulsed field ablation system had a 77.4% success rate at 12 months, compared to 63.5% for the Farawave sy…
Apr 5, 2026
Cardiology
Meta-analysis
DOACs show varied efficacy and safety profiles versus VKAs in atrial fibrillation patients with fall risk
Study compares blood thinners for atrial fibrillation patients with fall risk
A Bayesian network meta-analysis of 10 studies (5 RCTs, 5 observational) in AF patients with fall history/risk found apixaban ranked highest…
For atrial fibrillation patients at risk of falling, apixaban best prevents strokes while edoxaban best lowers major bleeding risks compared…
Apr 5, 2026
Cardiology
RCT
Left atrial appendage closure fails noninferiority test versus medical therapy in high-risk AF patients
Study finds device for stroke prevention in atrial fibrillation not as effective as medical therapy
A multicenter RCT in Germany randomized 912 high-risk AF patients to catheter-based left atrial appendage closure or physician-directed best…
A new German study found that a heart device to prevent strokes in atrial fibrillation was not as effective as standard blood-thinning medic…
Apr 4, 2026
Physical Medicine & Rehab
HIIT improves exercise capacity in cardiovascular rehabilitation for CAD, HF, and atrial fibrillation
Review suggests high-intensity interval training can help improve exercise capacity in heart patients
A rapid review and meta-analyses of cardiovascular rehabilitation programs for patients with coronary artery disease, heart failure, or atri…
High-intensity interval training may improve exercise capacity for heart patients with coronary artery disease or heart failure, according t…
medRxiv
Apr 3, 2026
Cardiology
Meta-analysis
Factor XIa inhibitors show higher stroke risk but lower bleeding risk versus DOACs in atrial fibrillation
New blood thinners cut bleeding risk but triple stroke risk in heart rhythm patients
A meta-analysis of 3 RCTs in 16,845 patients with atrial fibrillation found Factor XIa inhibitors were associated with a 3.32 times higher r…
New blood thinners for atrial fibrillation cut bleeding risk by 59% but triple the risk of stroke, raising concerns they may be too gentle t…
Apr 3, 2026
Cardiology
Meta-analysis
Catheter ablation for atrial fibrillation in cancer patients shows non-significant bleeding trend
Catheter ablation for atrial fibrillation shows similar outcomes in cancer and non-cancer patients
A meta-analysis of 69,819 patients from eight observational studies compared catheter ablation outcomes in atrial fibrillation patients with…
Catheter ablation for atrial fibrillation works similarly in cancer and non-cancer patients, with a trend toward more bleeding in cancer sur…
Apr 2, 2026
Cardiology
Meta-analysis
Machine learning shows moderate accuracy for predicting AF recurrence after catheter ablation in meta-analysis
Can AI predict if your irregular heartbeat will return after treatment?
A systematic review and meta-analysis of 17 studies found machine learning algorithms achieved a mean AUC of 0.81 for predicting atrial fibr…
Artificial intelligence can predict if an irregular heartbeat will return after treatment with an average accuracy score of 0.81, though res…
Apr 2, 2026
Cardiology
Cohort
Deep learning model predicts left atrial imaging from ECG, improves AF and HF risk stratification
Can a simple ECG reading predict your risk for heart rhythm problems?
An observational cohort study using UK Biobank data developed a deep learning model that predicts left atrial imaging indices from 12-lead E…
A routine 10-second heart test can now predict hidden risks for serious heart conditions better than current clinical scores.
medRxiv
Apr 2, 2026
Cardiology
Cohort
Higher prognostic nutritional index associated with lower MACE and mortality in AF and HFpEF patients
Study links better nutritional scores to lower heart risks in patients with two heart conditions
A retrospective cohort study of 734 patients with atrial fibrillation and HFpEF found that higher prognostic nutritional index (PNI) was ind…
Patients with better nutrition scores face a 63% lower risk of heart events and an 83% lower risk of death compared to those with poorer sco…
Frontiers
Apr 2, 2026
Cardiology
Meta-analysis
Meta-analysis finds sarcopenia associated with 44% higher atrial fibrillation risk in observational data
Sarcopenia linked to higher risk of atrial fibrillation in large review of studies
A systematic review and meta-analysis of observational cohort studies involving 7,358,442 participants found sarcopenia was associated with …
People with sarcopenia face a 44% higher risk of developing atrial fibrillation, according to a large review of over 7 million participants.
Frontiers
Apr 2, 2026
Neurology
Cohort
CEA2 scale predicts anterior circulation LVO stroke in Chinese community hospitals
Could four simple signs help community hospitals spot the most dangerous strokes faster?
A retrospective analysis of 722 patients from the STRESS registry derived a 4-item scale (CEA2) to predict acute anterior circulation large …
A new four-point checklist helps community hospitals quickly spot the most dangerous strokes that need immediate transfer for life-saving tr…
Frontiers
Mar 30, 2026
Cardiology
Meta-analysis
Surgical ablation reduces POAF but increases pacemaker risk in non-mitral valve surgery
For heart surgery patients with AFib, does adding a procedure to fix the rhythm help?
In a meta-analysis of 39,348 AF patients undergoing non-mitral valve surgery, concomitant surgical ablation was associated with a 27% reduct…
Adding a rhythm-fixing procedure during heart surgery significantly lowers AFib return rates but increases the chance of needing a permanent…
Mar 30, 2026