LAAC shows noninferior efficacy and reduced bleeding versus NOACs in non-valvular AF
New data shows left atrial appendage closure offers bleeding safety for some adults with atrial fibrillation
This meta-analysis of RCTs in adults with non-valvular AF found percutaneous left atrial appendage closure (LAAC) achieved noninferiority fo…
A large review of trials found that closing the heart appendage reduced bleeding compared to blood thinners. However, stroke risk trends wer…
Edoxaban trough concentration and PT predict major bleeding in very old AF patients
Blood thinner levels linked to bleeding in very old patients
This post hoc analysis of the ELDERCARE-AF RCT included 427 very old Japanese patients with atrial fibrillation and high bleeding risk. High…
Higher edoxaban levels in the blood may increase bleeding risk in patients 80 and older with atrial fibrillation.
Review links metabolic syndrome to 1.5 to 2 times higher atrial fibrillation risk
Metabolic syndrome raises atrial fibrillation risk by 1.5 to 2 times
This narrative review examines the association between metabolic syndrome and atrial fibrillation. The authors synthesize evidence suggestin…
Metabolic syndrome increases the risk of developing atrial fibrillation by 1.5 to 2 times, a finding that could help doctors target preventi…
Editorial argues emergency physicians are key to AF heart teams
Emergency doctors key to atrial fibrillation care, editorial says
This editorial argues that emergency physicians are indispensable members of atrial fibrillation heart teams. They enhance integration of ac…
An editorial argues emergency physicians should be core members of AF heart teams to improve care coordination and outcomes.
Routine prophylactic left atrial appendage closure did not significantly reduce the incidence of the primary composite endpoint
Routine valve closure did not significantly reduce stroke risk in heart surgery patients
In a randomized trial involving 2118 patients undergoing valve repair or replacement, surgical left atrial appendage occlusion failed to low…
A major surgery trial found that closing a heart chamber did not lower stroke risk compared to standard care for patients getting valve repa…
Network meta-analysis compares DOACs and VKAs for intracranial hemorrhage risk
Dabigatran may be safest for brain bleeding risk
This network meta-analysis of 127,267 patients with venous thromboembolism or atrial fibrillation found that all DOACs had lower risk of int…
All blood thinners beat warfarin for brain bleed risk, but dabigatran may be the safest choice.
OAC monotherapy offers optimal balance for secondary prevention in atrial fibrillation and stroke patients compared to combination strategies
Taking one blood thinner alone works best for heart and stroke patients compared to mixing medicines
A network meta-analysis of 14,104 patients suggests oral anticoagulant monotherapy is the most favorable strategy for secondary prevention i…
Doctors found that using just one blood thinner is safer and more effective than mixing it with other pills. This approach lowers stroke ris…
Meta-analysis finds lower bleeding risk with apixaban and rivaroxaban vs VKAs in dialysis patients with AF
New Blood Thinners Cut Bleeding Risk For Dialysis Patients
This meta-analysis of observational studies and RCTs compared apixaban or rivaroxaban with vitamin K antagonists in dialysis patients with a…
New blood thinners could save lives for dialysis patients by cutting bleeding and stroke risks while waiting for bigger studies to confirm t…
LAAC and DOACs match warfarin for stroke prevention in AF patients
LAAC and DOACs Cut Bleeding Risk Better Than Warfarin
A network meta-analysis of 78,594 AF patients found LAAC and DOACs offered similar protection against ischemic stroke as warfarin, while sig…
New research shows two new options for atrial fibrillation patients lower bleeding risks while keeping stroke protection the same as older d…
Guideline defines seven core outcomes for traditional Chinese medicine trials in atrial fibrillation
Doctors agree on seven key outcomes for atrial fibrillation trials
This guideline outlines a core outcome set for traditional Chinese medicine trials in atrial fibrillation. Seven outcomes were selected by 1…
A new standard list of seven outcomes will make it easier to compare atrial fibrillation trials and understand what truly matters to patient…
Sacubitril/Valsartan plus RFCA improves rhythm control in hypertensive NPAF patients
ARNI plus RFCA improves heart rhythm control in hypertension patients
This randomized controlled trial in 240 hypertensive patients with nonparoxysmal atrial fibrillation compared sacubitril/valsartan plus radi…
Adding sacubitril/valsartan to a heart procedure helped more patients stay in normal rhythm and lowered blood pressure markers.
Family history, prior arrhythmia, and anterior infarct location independently raise risk of ventricular fibrillation in STEMI patients
Family history and heart attack location raise risk of dangerous heart rhythms in young patients
This meta-analysis of 1807 cases and 2923 controls confirms that family history of sudden death, previous atrial fibrillation, and anterior …
A large study found that family history of sudden death, past atrial fibrillation, and front heart attacks increase the chance of dangerous …