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Anesthesiology & Pain Medicine
Meta-analysis
Efficacy of Laparoscopic Guided Transversus Abdominis Plane Block for Postoperative Pain Management
LTAP block reduces early pain after gallbladder removal surgery
LTAP blocks significantly reduce early postoperative pain scores compared to port-site infiltration in patients undergoing laparoscopic chol…
A specific nerve block technique can significantly lower pain levels for patients during the first 24 hours after gallbladder surgery.
NEJM
Sep 6, 2026
Drug Pipeline
Meta-analysis
Preoperative pregabalin 150 mg cuts pain and opioid use after laparoscopic cholecystectomy
Pregabalin May Reduce Pain After Gallbladder Surgery
This meta-analysis of randomized trials found that a single 150 mg preoperative dose of pregabalin significantly reduced 24-hour postoperati…
A single dose of pregabalin before surgery may lower pain scores and reduce the need for opioid medications after gallbladder removal.
medRxiv
Aug 23, 2026
Nutrition & Obesity Medicine
Cohort
Elevated iodine and selenium linked to pancreatic cancer while copper linked to acute pancreatitis
Too much iodine and selenium may harm your pancreas
This prospective cohort study analyzed 191,875 UK Biobank participants over a median 13 years.
New research shows high iodine and selenium levels increase pancreatic cancer risk while copper and magnesium may protect against inflammati…
Frontiers
Apr 29, 2026
Rheumatology
Cohort
Sarcopenia linked to higher acute cholecystitis risk in older adults with incidental gallstones
Muscle Loss May Predict a Painful Gallbladder Attack in Older Adults
A retrospective cohort study of 1,177 patients aged ≥65 years with incidental gallstones found sarcopenia was associated with a 3.6-fold inc…
Older adults with low muscle mass are 3.5 times more likely to develop a sudden, severe gallbladder infection than those with obesity.
Frontiers
Apr 14, 2026
Primary Care & Family Medicine
RCT
Informative video improves comprehension and satisfaction in laparoscopic cholecystectomy consent
A Simple Video Could Transform How You Understand Surgery
A single-center RCT of 264 patients in Turkey found that adding an informative video to standard verbal consent for laparoscopic cholecystec…
A short video helps patients remember surgery details better than a doctor's talk alone, boosting confidence and satisfaction before the ope…
Apr 11, 2026
Diabetes & Endocrinology
Cohort
METS-IR shows U-shaped link to gallstone disease risk, with inflection at 29.83
Could your body's insulin resistance score reveal your risk for gallstones? A new study finds a surprising U-shaped link
A cohort study of 52,723 participants found a nonlinear U-shaped association between the Metabolic Score for Insulin Resistance (METS-IR) an…
A new study of over 52,000 people found that your metabolic score for insulin resistance (METS-IR) has a surprising link to gallstone risk.
Frontiers
Mar 30, 2026