Research across Coronary Artery Disease
Related studies from across the Coronary Artery Disease family.
Clopidogrel monotherapy reduces bleeding risk to 2.1% versus 3.2% in patients with acute coronary syndromes
Trial shows clopidogrel alone reduces bleeding risk after heart procedures
This prespecified subgroup analysis of a randomized controlled trial involving 7758 patients with acute coronary syndromes found that clopid…
Patients with heart conditions may face fewer bleeding risks by switching to clopidogrel alone after a period of dual therapy.
Sirolimus-Eluting Balloon with Provisional Stenting for Small to Medium Coronary Arteries
Trial shows sirolimus-eluting balloon is comparable to standard stents
A randomized trial demonstrates that sirolimus-eluting balloon treatment is noninferior to systematic DES for target vessel failure in speci…
A new trial shows that a sirolimus-eluting balloon is as effective as standard stents for treating specific coronary artery blockages.
Evaluating Stepwise Dual Antiplatelet Therapy De-escalation in Patients Following Drug-Coated Balloon Angioplasty
Trial Shows Stepwise DAPT De-escalation for Coronary Heart Disease
A prespecified subgroup analysis of the REC-CAGEFREE II trial evaluates the safety of DAPT de-escalation in ACS patients undergoing DCB-only…
New data shows that switching to a simpler blood thinner regimen may be as safe as standard treatment for patients with coronary artery dise…
Impact of Percutaneous Coronary Intervention Complexity on Ticagrelor or Prasugrel Monotherapy Efficacy
Complex heart procedures do not change risks of certain medications
A post hoc analysis of the NEO-MINDSET trial evaluates if PCI complexity influences the safety and efficacy of potent P2Y inhibitor monother…
New analysis shows that complex heart procedures do not change the safety or effectiveness of specific blood-thinning medications.
Impact of Early Aspirin Withdrawal on Myocardial Infarction in Patients After PCI
Aspirin withdrawal shortly after heart procedures may increase heart attack risk
Early aspirin withdrawal within 30 days post-PCI significantly increases myocardial infarction risk, despite long-term reductions in bleedin…
Stopping aspirin within 30 days of a heart procedure may increase the risk of a heart attack in the first month.
Speckle-tracking echo detects coronary artery disease with 77% sensitivity and 75% specificity
Echocardiography Shows Moderate Accuracy for Detecting Coronary Artery Disease
This meta-analysis of 40 non-randomized studies (5,296 participants) found that speckle-tracking echocardiography (STE) has moderate diagnos…
A review of 40 studies shows that speckle-tracking echocardiography can help identify coronary artery disease with moderate accuracy.
Noninferiority of Ultra-thin Biodegradable Polymer Sirolimus Eluting Stents in Diabetic Patients
New stent type shows promise for patients with diabetes and heart disease
A multicenter trial confirms that ultra-thin biodegradable polymer sirolimus-eluting stents meet noninferiority goals compared to durable po…
A new ultra-thin stent may offer a reliable option for people with both diabetes and complex heart disease.
Drug-coated balloons reduce major adverse cardiac events in select coronary bifurcation lesions
Drug Coated Balloons Show Promise for Coronary Artery Disease
This narrative review synthesizes evidence regarding side branch treatment strategies and drug-coated balloons (DCB) for coronary bifurcatio…
New data suggests drug coated balloons may offer a safer way to treat complex heart artery blockages compared to standard plain balloons.
Ticagrelor and prasugrel show no statistically credible difference in 1-year MACE for ACS patients
Comparing Ticagrelor and Prasugrel for Patients with Heart Conditions After Surgery
This meta-analysis of retrospective new-user cohort studies analyzed 133,718 adults with acute coronary syndrome undergoing first PCI. The s…
A large study compared two heart medications to see which was safer and more effective for patients after a heart procedure.
Multimodal framework using Lp(a), hs-CRP, and colchicine addresses residual risk in Chinese CAD patients
New Framework Suggests Colchicine Use for Coronary Artery Disease
This perspective piece proposes a multimodal framework for assessing residual risk in Chinese patients with coronary artery disease. It sugg…
A new framework suggests using specific markers like hs-CRP and Lp(a) to help identify patients who may benefit from low-dose colchicine.
Angiography-derived FFR meets noninferiority for revascularization rate in stable coronary artery disease
New imaging method shows promise for heart artery procedures
This randomized trial of 401 patients with stable coronary artery disease found that angiography-derived FFR was noninferior to pressure wir…
A new wire-free imaging technique may offer a practical way to guide heart surgery decisions for patients with coronary artery disease.
EPA and DHA supplementation significantly lowers inflammatory markers in coronary artery disease patients
Fish oil supplements may lower inflammation in heart disease patients
This secondary analysis of a randomized trial involved 240 patients with stable coronary artery disease on statin therapy. Supplementation w…
A study shows that taking specific fish oils can lower certain markers of inflammation in people with coronary artery disease.