Low-use wrist-strap restraint strategy did not improve days free of delirium or coma compared with high-use strategy in mechanically ventilated adults.
ICU Wrist Restraints: The Surprising Truth About Using Fewer
This randomized clinical trial evaluated a restrictive, low-use wrist-strap physical restraint strategy versus a liberal, high-use strategy …
A major ICU trial found that using fewer wrist restraints did not help patients stay more alert or avoid confusion while on breathing machin…
Nurse-led sedation protocols reduce mortality and delirium in mechanically ventilated ICU patients
Nurse-led sedation protocols in intensive care may reduce patient mortality and complications
A systematic review and meta-analysis of 16 RCTs involving 1,887 mechanically ventilated ICU patients found nurse-led sedation protocols sig…
Nurse-led sedation protocols in intensive care significantly reduce patient death, confusion, and hospital stay length for those on breathin…
Prediction models for mortality in ICU patients with delirium show fair discrimination
Study develops models to predict mortality risk in ICU patients with delirium
This substudy of the AID-ICU trial developed clinical prediction models for 90-day and 1-year mortality in 632 adult ICU patients with delir…
New models using age, frailty, and cancer history can predict which ICU patients with delirium face higher risks of dying within 90 days or …
Benzodiazepines, Dexmedetomidine, and Physical Restraints Associated with Next-Day Delirium in Critically Ill Children
Study finds link between certain medications, restraints, and delirium in critically ill children
A secondary analysis of a pilot RCT dataset in 1,006 critically ill children across seven PICUs found previous-day benzodiazepine and dexmed…
Higher doses of sedatives like midazolam and any use of physical restraints are linked to increased confusion in critically ill children the…