CXCL13 quantification in PBMCs and plasma distinguishes Sézary syndrome from other cutaneous T-cell lymphomas and dermatoses
A simple blood test could spot a rare skin cancer faster
This cohort study analyzed CXCL13 expression in peripheral blood mononuclear cells (PBMCs) and plasma concentrations in patients with suspec…
A simple blood test for a protein called CXCL13 may help doctors catch a rare, aggressive skin cancer that often looks like eczema for years…
Meta-analysis of mercury exposure in children associates with higher prevalence of asthma, atopic dermatitis, and other allergic outcomes
A Hidden Link in Your Child's Allergies Might Be in Your Diet
This systematic review and meta-analysis examined sixteen studies involving children with measured mercury exposure in East Asia and Europe.
Mercury exposure in early life is linked to asthma, eczema, and other allergies in children, with up to 22% of exposed kids affected.
Early proactive TCS for infant AD linked to lower food allergy rates at age 3
Early eczema treatment in infants linked to lower food allergy risk at age three
A 3-year follow-up RCT of 590 children found early proactive topical corticosteroid treatment for infant atopic dermatitis was associated wi…
Treating infant eczema early and consistently lowered food allergy rates at age three, with fewer cases of egg allergy and pollen sensitivit…
AI pipeline shows substantial agreement with dermatologists for grading atopic dermatitis erythema severity
Can AI help doctors measure eczema severity from photos?
A cross-sectional validation study of 41 AD lesion images found an AI pipeline demonstrated substantial agreement with dermatologist consens…
An AI system graded eczema redness 81% of the time like expert doctors, showing promise for tracking flare-ups from photos.
Meta-analysis finds oral JAK inhibitors increase HDL and LDL cholesterol levels in patients from RCTs
Common arthritis and skin drugs linked to cholesterol changes, analysis finds
A systematic review and meta-analysis of 13 phase 2 and 3 RCTs involving 5,658 patients found treatment with oral JAK inhibitors (baricitini…
Common arthritis and skin drugs can raise both 'good' and 'bad' cholesterol levels, a review of nearly 4,000 patients shows.
Parental autoimmune diseases associated with increased risk of asthma, eczema in offspring
Parental autoimmune diseases linked to higher allergy risk in children
A systematic review and meta-analysis of 12 studies found maternal autoimmune diseases were associated with increased odds of asthma (OR 1.2…
Children of parents with autoimmune diseases face higher risks for asthma, eczema, and hay fever, according to a new analysis of existing he…
Genetic study links H. pylori susceptibility to HLA and innate immunity genes, suggests causal disease relationships
Large genetic study finds links between H. pylori infection susceptibility and autoimmune diseases
A meta-analysis of up to 140,863 Japanese and European individuals identified significant genetic associations for H.
A large genetic study reveals specific immune system genes linked to H. pylori infection and autoimmune diseases like type 1 diabetes and Ha…
Network meta-analysis ranks upadacitinib highest for efficacy in moderate-to-severe atopic dermatitis
Study compares eczema medications, finds upadacitinib 30 mg ranked highest for effectiveness
A network meta-analysis of 16,334 adults with moderate-to-severe atopic dermatitis compared approved systemic targeted therapies.
Upadacitinib 30 mg ranked highest for clearing skin and reducing itch among approved eczema medications in a new analysis of over 16,000 pat…
Placebo effect observed in double-blinded food challenges for dogs with atopic dermatitis
Study finds placebo effect complicates food allergy testing in dogs with skin condition
A randomized, double-blinded, placebo-controlled trial in 12 dogs with atopic dermatitis and adverse food reactions found 91.7% tested posit…
Most dogs with itchy skin reacted to food challenges, but half also reacted to a fake diet, showing the placebo effect makes allergy tests u…
Systematic review links PPARγ to atopic dermatitis pathogenesis and identifies it as a potential therapeutic target
Review suggests a protein target may be linked to eczema and could lead to new treatments
A systematic review synthesizes mechanistic evidence linking peroxisome proliferator-activated receptor gamma (PPARγ) to atopic dermatitis p…
A protein called PPARγ could be a key target for new eczema treatments, as it helps restore skin barrier function and regulate immune respon…
Topical PDE4 inhibitors show efficacy in pediatric atopic dermatitis meta-analysis
Could a new cream help kids with eczema find relief faster?
A meta-analysis of 5 RCTs (n=1877) in pediatric mild-to-moderate atopic dermatitis found topical PDE4 inhibitors were associated with higher…
A new class of eczema creams linked to faster relief and better skin clearance in kids, with no increase in side effects compared to standar…
Review suggests chemokine inhibition as prospective therapeutic target for atopic dermatitis
Review suggests chemokine pathways may be promising targets for eczema treatment
A review of basic and clinical research in patients with AD and AD model mice found that chemokine ligand-receptor interactions regulate imm…
Blocking specific immune signals in eczema skin reduced inflammation in mice, suggesting a new treatment path as human trials progress.