TP53 and PTEN mutations detected in 68% and 47% of ovarian and endometrial cancer samples respectively in a retrospective cohort.
Genetic markers found in swabs may help spot ovarian and endometrial cancers
This retrospective cohort study evaluated 238 women across three tertiary hospitals between 2018 and 2023. TP53 mutations were identified in…
A new look at genetic markers in swabs shows they appear in most ovarian and endometrial cancer cases, offering a potential new way to find …
Narrative review on precision prevention for women with inherited gynecologic cancer susceptibility
New Plan Cuts Cancer Risk for High-Risk Women
This narrative review addresses ovarian, endometrial, and fallopian tube cancer in women with inherited gynecologic cancer susceptibility. T…
Women with strong family histories of ovarian or uterine cancer can now take smarter, personalized steps to reduce their risk — and it’s cha…
Narrative review on AI and digital pathology for breast and gynecologic cancers
New AI Tools Read Tumor DNA Like a Book
This narrative review synthesizes evidence on integrating digital and molecular pathology with AI and machine learning for breast and gyneco…
Combining microscope images with genetic data gives doctors a much clearer picture of how to treat cancer patients.
Narrative review links microbiome dysbiosis to gynecological cancer pathogenesis and potential therapeutic applications.
Microbiome changes may help explain how gynecological cancers start and grow.
This narrative review examines the role of the human microbiome in gynecological malignancies, including cervical, ovarian, endometrial, vul…
New review suggests microbiome shifts could be key to understanding gynecological cancers, opening doors for better prevention and treatment…
GWAS meta-analysis identifies genetic risk loci for female genital tract polyps in women.
New DNA clues link common gynecological issues to endometriosis and cancer risks.
This GWAS meta-analysis examined 48,400 cases and 477,134 controls across four biobanks to identify risk loci for female genital tract polyp…
A massive DNA study of nearly half a million women reveals genetic links between common gynecological polyps, endometriosis, fibroids, and e…
Systematic review and meta-analysis of Mendelian randomization studies examining T2DM and cancer associations.
Diabetes Linked to Two Specific Cancers
This systematic review and meta-analysis of Mendelian randomization studies evaluated the association between type 2 diabetes mellitus and s…
Type 2 diabetes raises the risk of pancreatic and endometrial cancers, according to a new analysis of genetic studies.
Untargeted urinary proteomics identifies dysregulated biomarkers in women with endometrial cancer versus controls.
New Urine Test Could Spot Endometrial Cancer Early
This case–control study evaluated untargeted label-free LC-MS/MS mass spectrometric approaches combined with bioinformatics in 40 women (20 …
A new urine test analyzes hundreds of proteins to spot endometrial cancer early without invasive biopsies.
Tumor budding associates with adverse clinicopathological features and reduced overall survival in cervical and endometrial cancer.
Tumor Budding Linked to Worse Outcomes in Cervical and Endometrial Cancer
This Bayesian meta-analysis of 18 observational cohort studies involving 3320 patients with cervical or endometrial cancer evaluated the pro…
Small clusters of cells breaking away from cervical and endometrial tumors signal more aggressive disease and worse survival outcomes.
Molecular-profile guided adjuvant treatment shows cost-effectiveness versus standard VBT in HIR-EC
Can a new cancer test save money without sacrificing quality of life?
A phase 3 RCT of 564 women with early-stage high-intermediate risk endometrial cancer found molecular-integrated-profile guided adjuvant tre…
A new cancer test guided by molecular profiles cut healthcare costs for endometrial cancer patients without lowering their quality of life o…
GWAS meta-analysis finds female-specific adiposity genetics linked to endometrial cancer risk
Why does body fat affect women's cancer risk differently than men's?
A genome-wide association study meta-analysis of genetic data from 2 million people identified a fourfold larger female-specific genetic com…
A massive genetic study of 2 million people reveals that the link between body fat and endometrial cancer is uniquely female. Researchers fo…
Intrauterine manipulator use in minimally invasive hysterectomy for endometrial cancer linked to lower disease-free survival
Could a common surgical tool affect cancer recurrence after hysterectomy?
A meta-analysis of 10,805 endometrial cancer patients undergoing minimally invasive hysterectomy found intrauterine manipulator use was asso…
A new analysis suggests a tool used during minimally invasive hysterectomy for endometrial cancer might be linked to a higher chance of the …
Multimodal analgesia linked to lower opioid use and pain scores after endometrial cancer surgery
Study finds certain pain management approaches linked to less opioid use after endometrial cancer surgery
A retrospective cohort study of 650 women undergoing endometrial cancer surgery found that multimodal or regional-based analgesic regimens w…
Women receiving combined pain relief after endometrial cancer surgery reported lower pain scores and used fewer opioids on the first day com…