FDA Approves Dapagliflozin for Heart Failure Risk Reduction and Glycemic Control in Type 2 Diabetes
FDA approves a diabetes drug that also helps protect the heart from failure.
The FDA has approved dapagliflozin to reduce the risk of hospitalization for heart failure in adults with type 2 diabetes and established ca…
FDA approves a diabetes pill that lowers blood sugar and reduces heart failure hospitalization for adults with type 2 diabetes and heart ris…
FDA Approves Dapagliflozin Tablets (dapagliflozin) to Reduce Heart Failure Hospitalization Risk in Adults with Type 2 Diabetes
FDA approves a diabetes drug that also helps protect the heart.
The FDA has approved dapagliflozin tablets to reduce the risk of hospitalization for heart failure in adults with type 2 diabetes mellitus a…
A new diabetes drug now protects the heart by lowering hospitalization risks for adults with type 2 diabetes and existing heart disease.
Exercise training improves multiple outcomes in frail older adults with heart failure
Can exercise help frail older adults with heart failure feel better and move more freely?
A systematic review of randomized controlled trials in frail adults aged ≥60 years with heart failure found that exercise training significa…
Exercise training for frail older adults with heart failure improved symptoms, mobility, mood, and blood markers in studies across Japan and…
AI approaches show potential for mapping brain-heart network interactions in neurocardiology
Can AI help us understand the hidden conversation between our brain and heart?
A systematic review explores artificial intelligence approaches for mapping and predicting brain-heart network dynamics across conditions li…
Artificial intelligence may decode the silent conversation between your brain and heart to spot hidden patterns in conditions like heart fai…
Planned HF hospitalization program linked to lower costs, shorter stays in small retrospective study
Planned hospitalizations for heart failure linked to lower costs and shorter stays
A retrospective single-center study of 20 patients with recurrent HF hospitalizations compared the Kurume-HEARTS program (planned hospitaliz…
A structured heart failure program lowered costs and shortened stays compared to unplanned emergency visits, though it did not reduce how of…
Beta-blocker discontinuation noninferior to continuation in stable post-MI patients without heart failure
Stable heart attack patients may safely stop beta-blockers after one year, study finds
A randomized, open-label, noninferiority trial in 2540 stable post-MI patients with LVEF ≥40% and no heart failure who had received beta-blo…
Stable heart attack patients who stop beta-blockers after a year face similar risks to those who keep taking them, according to a major stud…
HIIT improves exercise capacity in cardiovascular rehabilitation for CAD, HF, and atrial fibrillation
Review suggests high-intensity interval training can help improve exercise capacity in heart patients
A rapid review and meta-analyses of cardiovascular rehabilitation programs for patients with coronary artery disease, heart failure, or atri…
High-intensity interval training may improve exercise capacity for heart patients with coronary artery disease or heart failure, according t…
GLP-1 receptor agonists reduce new-onset heart failure risk in patients with diabetes or obesity
Could diabetes drugs also help protect the heart from failure?
A meta-analysis of 6 RCTs involving 52,752 participants without heart failure found GLP-1 receptor agonists decreased new-onset HF risk (HR=…
Diabetes drugs like semaglutide lower the risk of new heart failure by 23% in people with Type 2 diabetes or obesity, offering heart protect…
Covariate adjustment method for hierarchical outcomes improves statistical power in win ratio analyses
New statistical method may improve analysis of complex clinical trial outcomes
Methodological research using simulation studies and EMPEROR-Preserved trial data found that covariate adjustment for prognostic variables c…
A new statistical method boosts trial power when analyzing complex outcomes like hospitalizations and deaths by adjusting for patient charac…
RAS Inhibitors After TAVR Associated With Reduced Mortality in Meta-Analysis of 36,000 Patients
Heart medication after TAVR valve procedure linked to lower death risk in analysis
A Bayesian meta-analysis of 12 observational studies in 35,988 patients undergoing TAVR for aortic stenosis found RAS inhibitor therapy was …
Taking certain heart medications after a TAVR valve procedure is linked to a lower risk of death and fewer hospitalizations for heart failur…
Black participants less represented in US heart failure registries than in clinical trials
Heart failure registries included fewer Black participants than clinical trials in US study
A systematic review and meta-analysis of 62 US heart failure trials and 15 registries (2010-2019) found Black participants were significantl…
Heart failure registries in the US included fewer Black participants than clinical trials, revealing a gap in real-world research representa…
Systematic review outlines role of mitochondrial DNA mutations in heart failure pathogenesis
Review explores how mitochondrial DNA mutations may contribute to heart failure
A systematic review summarizes evidence on mitochondrial DNA mutations in heart failure. The review describes pathogenic mechanisms includin…
Mitochondrial DNA mutations can cause heart failure by disrupting energy production, increasing harmful molecules, and triggering inflammati…