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Home › Conditions › HPV infection

HPV infection

Subtypes of HPV infection

Human Papillomavirus Infection 9 Epidermodysplasia verruciformis 1

13 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for HPV infection

10 trials tracked for HPV infection: 2 in phase 3 or 4 and 1 with published results. The most-cited published study has 2 citations.

10Trials tracked
2Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 4 2 Phase 1 1 Other / NA 7
  1. Phase 4 HPV Vaccination Study in Postpartum Women Completed · 2 cited
  2. Phase 4 Does the HPV Vaccine Cause the Same Response in Adolescent Kidney and Liver Transplant Patients as in Healthy Controls? Completed
  3. Phase 1 Study With Candida Antigen for Treatment of Warts Completed
  4. N/A Thermocoagulation for Treatment of Precancerous Cervical Lesions Completed
  5. N/A HPV-Based Screen-and-Treat Demonstration Project in Lilongwe Completed
  6. N/A Identification and Treatment of Cervical Abnormalities in Perú Through Integration of Pocket Colposcopy and Telemedicine Completed
Show 4 more trials
  1. N/A Adaptation Of An HPV Education Resource To Promote HPV Vaccination Completed
  2. N/A Reduced-intensity Therapy for Oropharyngeal Cancer in Non-smoking HPV-16 Positive Patients Completed
  3. N/A 1:1 Comparison of the Pocket Colposcope in Kenya Completed
  4. N/A Self-Testing Options in the Era of Primary HPV Screening for Cervical Cancer Trial Completed

Showing the 10 most-cited and recently-updated of 10 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found For clinicians

HPV infection: what the trials found

Clinical evidence confirms the availability of Gardasil9 for HPV prevention, with data showing that 174 participants completed a 2-dose vaccination regimen in a study of 225 patients 1. Additionally, Quadrivalent HPV vaccines targeting types 6, 11, 16, and 18 have been established in clinical practice 2.

The prevalence of baseline titers suggestive of natural inoculation or prior vaccination to HPV 16 was observed in 91% of participants in a study evaluating Gardasil9 1.

Recent results — preliminary, needs further review

  • A large-scale study (N=1250) evaluated the use of VIA and thermocoagulation for management 4.
  • Research is ongoing regarding the use of pocket colposcopes to identify lesions, with reported detection rates ranging from 0% to 21.1% across different cohorts 5.
  • Studies are investigating the efficacy of a pocket colposcope combined with thermocoagulation for treatment 6.
  • A study on thermocoagulation reported varying pain scores and a range of treatment-related adverse event rates (0% to 51.2%) 9.

For the clinician treating this condition

  • Gardasil9 is established as an option for HPV prevention, with high rates of completion for the 2-dose regimen 1.
  • Quadrivalent vaccines targeting types 6, 11, 16, and 18 are established interventions for HPV 2.

AI synthesis of 6 cited trials, updated Jun 28, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Induction Nivolumab Before CRT Misses Feasibility Threshold in High-Risk HPV+ OPC
Oncology RCT
Induction Nivolumab Before CRT Misses Feasibility Threshold in High-Risk HPV+ OPC Can a new approach reduce relapse in high-risk throat cancer? Early results show promise but raise safety concerns
In a phase II RCT of high-risk HPV-positive oropharyngeal cancer patients, induction nivolumab before chemoradiation did not meet the predef…
Adding immunotherapy before standard treatment reduced cancer relapse in high-risk throat cancer patients, though severe side effects preven…
Mar 30, 2026

Questions about HPV infection

Does the female reproductive tract microbiome affect health during an HPV infection?

The microbiome of the female reproductive tract plays a significant role in health during an HPV infection, as imbalances in bacteria can promote infection and progression.

Full answer →
How does innate immune recognition affect the progression of Cervical Cancer and HPV?

HPV evades innate immune detection by suppressing PRR signaling and NLRP3 inflammasome, enabling persistent infection and cervical cancer progression.

Full answer →