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Allergy & Immunology
RCT
House dust mite immunotherapy reduces IgE and symptoms in Indonesian children with allergic rhinitis and asthma
Could weekly dust mite shots help Indonesian children breathe easier with less medicine?
A small RCT of 41 Indonesian children with allergic rhinitis and asthma found 14 weeks of weekly subcutaneous HDM immunotherapy significantl…
Weekly dust mite shots helped Indonesian children with allergies and asthma breathe easier, needing fewer pills and feeling less discomfort …
Apr 9, 2026
Oncology
Cohort
Hospitalized malignant neoplasm patients show high comorbidity burden and distinct disease patterns across 163 Chinese hospitals
Hospitalized cancer patients in China often have other serious health conditions
This retrospective cohort study examined 107,029 hospitalized patients with malignant neoplasms across 163 hospitals in Zhanjiang, China.
Hospitalized cancer patients in China often face five other serious health conditions, with rural residents, men, and those aged 65 or older…
Frontiers
Apr 9, 2026
Allergy & Immunology
Cohort
Baseline inflammation patterns in severe asthma patients receiving biologic therapy
Severe asthma patients with neutrophilic patterns had lower lung function and more sleep apnea
This retrospective observational cohort study analyzed 103 patients with severe asthma treated with biologic agents.
Severe asthma patients with neutrophilic patterns had lower lung function and more sleep apnea than those with other inflammation types.
Frontiers
Apr 9, 2026
Rheumatology
Cohort
Regional anesthesia with propofol sedation versus general anesthesia in unilateral total knee arthroplasty patients
Numb Legs, Faster Walks: New Knee Surgery Data
This retrospective cohort study evaluated 250 patients undergoing unilateral total knee arthroplasty to compare regional anesthesia with mon…
New knee surgery data shows regional anesthesia leads to faster walking and fewer readmissions without increasing dangerous blood clot risk.
Frontiers
Apr 9, 2026
Pulmonology & Critical Care
Daily Vitamin D increased HDAC2 and 25(OH)D levels in stable COPD patients without improving pulmonary function
Vitamin D supplement increased a protein marker in five COPD patients
This experimental study evaluated the effect of daily 5000 IU Vitamin D in five stable COPD patients over three months.
Daily Vitamin D supplements raised a protein marker in five COPD patients, but the study found no significant improvement in lung function a…
medRxiv
Apr 9, 2026
Pulmonology & Critical Care
RCT
Low-dose theophylline shows modest FEV improvement but no exacerbation reduction in mild to moderate COPD
Can a low-dose pill help people with mild COPD breathe easier?
A 12-month randomized trial in 734 Chinese patients with mild to moderate COPD found oral low-dose theophylline (100 mg twice daily) produce…
A low-dose theophylline pill helped mild COPD patients exhale slightly better but did not reduce dangerous flare-ups during a year-long stud…
Apr 8, 2026
Diabetes & Endocrinology
RCT
Liraglutide reduces OSA severity in patients with COPD and obesity in exploratory analysis
Could a weight loss drug help people with COPD breathe easier at night?
A secondary exploratory analysis of a 40-week RCT in 40 patients with COPD and overweight/obesity found liraglutide (3.0 mg) significantly r…
A weight loss drug reduced breathing pauses and oxygen drops for people with COPD and sleep apnea, improving general health while day-time s…
Apr 8, 2026
Allergy & Immunology
Sys. Review
Systematic review finds moderate to substantial concordance among fungal sIgE detection kits for asthma
Review finds variation in tests for fungal allergy in asthma patients
A systematic review of 16 human studies evaluating 32 commercial fungal sIgE detection kits found moderate to substantial concordance with t…
Asthma fungal allergy tests often give different results because commercial kits use different methods and cut-off points, making it hard to…
Frontiers
Apr 8, 2026
Pulmonology & Critical Care
Genetic analysis links oral microbiota to COPD risk in East Asian population
Could the bacteria in your mouth affect your risk of COPD?
A genetic causal inference and bioinformatics analysis using East Asian GWAS data identified 48 oral microbial taxa associated with COPD ris…
A study in East Asian people links 48 types of mouth bacteria to COPD risk and identifies a gene and six existing drugs that might target it…
medRxiv
Apr 8, 2026
Pulmonology & Critical Care
FDA Approval
FDA Approves Nintedanib Capsules (nintedanib esylate) for Idiopathic Pulmonary Fibrosis and Progressive Fibrosing ILDs
FDA approves a new drug to treat two types of progressive, scarring lung diseases
The FDA has approved nintedanib capsules for the treatment of adults with idiopathic pulmonary fibrosis (IPF) and for adults with chronic fi…
FDA approves new drug to treat two types of progressive, scarring lung diseases that make lungs stiff and hard to breathe.
FDA
Apr 7, 2026
Pulmonology & Critical Care
FDA Approval
FDA Approves Nintedanib Capsules (nintedanib esylate) for Idiopathic Pulmonary Fibrosis and Progressive Fibrosing ILDs
FDA approves a new drug to treat two serious, scarring lung diseases in adults
The FDA has approved nintedanib capsules for the treatment of adults with idiopathic pulmonary fibrosis (IPF) and for adults with chronic fi…
FDA approves new drug nintedanib to treat two serious, scarring lung diseases in adults with progressive conditions.
FDA
Apr 7, 2026
Rheumatology
Meta-analysis
Rheumatoid arthritis is associated with a 58% higher risk of COPD compared to the general population
Rheumatoid Arthritis Patients Face Higher Risk of Developing Chronic Lung Disease
This systematic review and meta-analysis evaluated 1,710,600 individuals to assess the prevalence and risk of chronic obstructive pulmonary …
People with rheumatoid arthritis face a significantly higher risk of developing chronic obstructive pulmonary disease compared to the genera…
NEJM
Apr 6, 2026