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Home › Conditions › Pelvic Pain

Pelvic Pain

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for Pelvic Pain

14 trials tracked for Pelvic Pain: 3 in phase 3 or 4 and 1 with published results. The most-cited published study has 9 citations.

14Trials tracked
3Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 4 3 Phase 2 2 Other / NA 9
  1. Phase 4 Chronic Pain Risk Associated With Menstrual Period Pain Completed · 9 cited
  2. Phase 4 Tenaculum Pain Control Study Completed
  3. Phase 4 Effect of Nicotine on Chronic Pelvic Pain Completed
  4. Phase 2 Transcranial Direct Stimulation in Chronic Pelvic Pain Completed
  5. Phase 2 Vaginal Diazepam for the Treatment of Female Pelvic Pain Completed
  6. N/A Endometriosis Group Care Completed
Show 8 more trials
  1. N/A POCUS Assessment of Bladder Fullness for Girls Awaiting Radiology-Performed Transabdominal Pelvic Ultrasound Completed
  2. N/A Onabotulinumtoxin A Versus Kenalog for Chronic Pelvic Pain Completed
  3. N/A Enriched Environments in Endometriosis Completed
  4. N/A Intravesical Liposomes for Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS) Completed
  5. N/A Surgical Treatment of Pelvic Joint Instability in Patients With Severe Pelvic Girdle Pain After Pregnancy and Trauma Completed
  6. N/A Does 3D Laparoscopy Improve Vaginal Cuff Suture Time? Completed
  7. N/A Intra-vaginal Electrical Stimulation Device Compared to Sham Device for Chronic Pelvic Pain Completed
  8. N/A Program to Overcome Pelvic Pain Study Completed

Showing the 14 most-cited and recently-updated of 14 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found Updated — new results For clinicians

Pelvic Pain: what the trials found

Cyclic microgestin 1/20 (an oral contraceptive) was evaluated in a phase 4 trial (N=353) for pelvic pain. The trial reported a statistically significant change in participant bladder pain sensitivity from baseline (p=.02), but no significant changes in quantitative sensory testing parameters for pelvic hyperalgesia (p=0.2315) or in EEG-recorded cortical activity (p=.393). Thus, while some pain sensitivity improved, other measures of pain processing did not show significant change.

Intracervical lidocaine injection was studied in a phase 4 trial (N=74), but no outcome data are provided in the extracted information. Therefore, no conclusions can be drawn from this trial regarding its efficacy for pelvic pain.

A phase 4 trial (N=20) evaluated placebo for pelvic pain, reporting a pain score of 7.1 at baseline, 6.4 at a later time, and 6.9 at another time. However, no statistical comparison or p-value is provided, so the significance of these changes is unknown.

Recent results — preliminary, needs further review

  • A peer support intervention (PEEPS) for endometriosis pain is being studied (N=35), but no outcome data are available yet.
  • Diazepam (phase 2, N=50) showed no significant improvement in pain (VAS p=0.62), pelvic floor distress (PFDI-20 p=0.66), or McGill Pain Questionnaire scores (p=0.88) at 4 weeks, suggesting a lack of benefit in this small trial.
  • Transcranial direct current stimulation (phase 2, N=35) is being investigated, but no outcome data are provided.
  • Environmental enrichment (N=56) and a yoga program (N=36) are being studied; the yoga trial reported feasibility outcomes (retention, attendance, self-efficacy) but no pain efficacy data.
  • Onabotulinumtoxin A (N=21) showed trends toward pain reduction (VAS change -2 vs -1, p=0.072) but did not reach statistical significance; other pain measures (BPI) showed mixed changes.

For the clinician treating this condition

  • Cyclic microgestin 1/20 may improve bladder pain sensitivity in pelvic pain, but other pain processing measures were not significantly changed.
  • Diazepam showed no significant benefit for pelvic pain in a small phase 2 trial.
  • Onabotulinumtoxin A showed a trend toward pain reduction but did not reach statistical significance.
  • Many recent interventions lack sufficient data or show non-significant results, highlighting the need for further research.

AI synthesis of 0 cited trials, updated Aug 7, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
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Jul 6, 2026