Bronchoscopic resection and individualized therapy may treat tracheobronchial tuberculosis presenting as endobronchial masses
Rare airway tuberculosis found in young man's bronchial mass
This case report and literature review describes a 21-year-old male with tumorous tracheobronchial tuberculosis complicated by infiltrative …
A 21-year-old's airway mass turned out to be a rare form of tuberculosis. Early removal and treatment led to marked improvement.
Pulmonary TB History Linked to Higher COPD Odds
Past tuberculosis infection significantly increases risk of developing lung disease
Meta-analysis of over 1 million people finds prior pulmonary TB associated with 2.65 times higher odds of COPD.
A history of pulmonary tuberculosis is linked to a much higher risk of developing chronic obstructive pulmonary disease, especially in certa…
MiniDock MTB Test Shows High Sensitivity and Specificity for Tuberculosis Detection
A new test finds TB in people who cough up nothing
This prospective cross-sectional study evaluated the MiniDock MTB test using sputum and tongue swabs in 1380 patients with presumptive pulmo…
A new test found tuberculosis in over 85% of patients who could not produce a cough sample, offering a faster way to diagnose the disease in…
Systematic review and meta-analysis shows reduced lung function in children with post-tuberculosis treatment compared to healthy controls
Children treated for TB may face lasting lung damage
This systematic review and meta-analysis evaluated pooled mean z-scores for FEV1, FVC, and FEV1/FVC ratio in children (≤18 years) with pulmo…
Kids treated for TB can have lasting lung problems, even after recovery, a new analysis finds.
Retrospective Study Shows 3D ResNeXt Classifier Distinguishes NTM-LD from PTB in 409 Patients
New AI Tool Helps Doctors Tell Two Lung Infections Apart
This retrospective cohort study evaluated a 3D ResNeXt-based deep learning classifier in 409 patients with microbiologically confirmed diagn…
A new computer program can help doctors tell two similar lung diseases apart using CT scans.
Phase 1 trial shows ESAT6-MPT64 skin test safe with high sensitivity for active TB
New TB Skin Test Shows Promise in Early Human Trial
A Phase 1 randomized clinical trial in 60 participants (30 healthy controls, 30 active TB patients) found the recombinant ESAT6-MPT64 skin t…
A new skin test for tuberculosis proved safe and accurately identified active cases in the first human trial, offering a simpler, cheaper al…
Age-period-cohort analysis shows declining bacteriologically confirmed pulmonary tuberculosis incidence in Hunan Province, China, 2009–2023
For decades, the fight against tuberculosis (TB) has followed a familiar script. But new data reveals the story is changing. The faces of those most vulnerable are shifting in surprising ways
This review analyzed population-based surveillance data from Hunan Province, China, from 2009 to 2023 to assess trends in bacteriologically …
Tuberculosis risk now peaks in young adults and the elderly, with the sharpest rise in the oldest age group, signaling a shift in who needs …
Combined radiomics-clinical model improves AP for differentiating pulmonary tuberculosis from non-tuberculous lung lesions on CT
New CT model may help distinguish tuberculosis from other lung lesions in some patients
This observational study evaluated 900 patients with pulmonary tuberculosis or non-tuberculous solid lung lesions.
A new computer model using CT scans and clinical data outperforms standard methods in distinguishing tuberculosis from other lung lesions in…
Clinical prediction model differentiates NTM pulmonary disease from tuberculosis in hospitalized patients
Can a simple checklist help doctors tell two serious lung infections apart?
A retrospective cross-sectional cohort study of 351 hospitalized patients with microbiologically confirmed NTM-PD or PTB developed a six-var…
A simple checklist using age, gender, and lung conditions helps doctors quickly tell apart two serious lung infections that need different t…
Pilot project describes TB contact management in Ugandan households without reported outcomes
Pilot project in Uganda manages TB risk among household contacts
A pilot project report describes case finding and comprehensive management of household contacts of people with pulmonary TB in Uganda.
A pilot project in Uganda manages tuberculosis risk for household contacts of people living with TB.
Research across Tuberculosis
Related studies from across the Tuberculosis family.
Risk prediction models for anti-tuberculosis drug-induced liver injury show pooled AUC of 0.81
Risk Prediction Models Help Identify Liver Damage from Tuberculosis Drugs
This meta-analysis of 26 studies involving 41,734 cases evaluated risk prediction models for anti-tuberculosis drug-induced liver injury (AT…
New risk models can help identify patients at risk for liver injury when taking tuberculosis medications, especially those with specific hea…
Sensititre MYCOTB shows high diagnostic accuracy for rifampicin and isoniazid in tuberculosis isolates
New test shows high accuracy for detecting drug resistant tuberculosis
This meta-analysis of 1,728 isolates evaluates the diagnostic performance of Sensititre MYCOTB against reference drug susceptibility testing…
A new testing method shows high accuracy in identifying which drugs can successfully treat drug-resistant tuberculosis infections.
Expanded TB Screening in HIV Inpatients Shows No Benefit
Expanded Screening Does Not Speed Tuberculosis Treatment for HIV Patients
In HIV-positive hospital inpatients, expanded TB screening with Xpert Ultra and LF-LAM did not improve treatment initiation or 8-week mortal…
A large trial in Tanzania and Mozambique found that expanded screening did not speed up tuberculosis treatment or reduce deaths for patients…
Tuberculosis prevalence among children with severe acute malnutrition is 13% (95% CI: 11-16%)
Tuberculosis is common among children with severe acute malnutrition
This meta-analysis of 33,869 children across 15 countries identifies a pooled tuberculosis prevalence of 13% in those with severe acute maln…
Over 13% of children suffering from severe acute malnutrition also have tuberculosis, highlighting a critical need for integrated screening.
WGS-based tools provide high specificity and sensitivity for rifampicin, isoniazid, and fluoroquinolone resistance detection
New tools help doctors identify drug resistant tuberculosis strains
This meta-analysis of 144,623 M. tuberculosis genomes evaluates six open-access WGS-based drug susceptibility testing prediction tools. The …
New computer tools can accurately predict if common drugs will work against tuberculosis, helping doctors choose the right treatment faster.
TB-TST mobile application increases treatment success to 82% in drug susceptible tuberculosis
Mobile App Improves Success Rates for Tuberculosis Treatment
This pragmatic randomized controlled trial of 555 individuals with newly diagnosed drug susceptible tuberculosis found that the TB-TST inter…
A mobile app and urine tests helped more patients complete their tuberculosis treatment compared to standard care alone.
Modified regimens for drug-resistant tuberculosis show higher success rates than standard regimens in Cameroon
Modified drug regimens show higher success for drug-resistant tuberculosis
This systematic review and meta-analysis of 2,351 patients with drug-resistant tuberculosis (DR-TB) in Cameroon found that modified regimens…
A new analysis shows modified treatment plans can improve success rates for patients fighting drug-resistant tuberculosis.
Baseline auramine count predicts tuberculosis failure or relapse by 5% higher odds per 100 bacilli
Auramine Levels May Predict Treatment Success for Tuberculosis Patients
This secondary analysis of an RCT involving 321 patients treated with double-dose R. found that quantitative baseline auramine significantly…
A study suggests that specific bacteria counts at the start of treatment can help predict if a patient with tuberculosis will experience a r…
HIV co-infection triples MDR-TB mortality risk; low BMI and anaemia also raise risk
HIV and other risk factors linked to multidrug-resistant tuberculosis deaths
This meta-analysis of 36,693 patients with multidrug-resistant tuberculosis (MDR-TB) found that HIV co-infection, lower educational attainme…
Patients with multidrug-resistant tuberculosis face higher risks of death if they also have HIV, low body mass index, or certain other healt…
Rifapentine 15 mg/kg and 20 mg/kg yield higher culture conversion than standard 6-month regimen
Trial Shows Rifapentine Dosage Impacts Tuberculosis Treatment Outcomes
This Phase 2/3 Stage 1 randomized controlled trial of 400 adults with pulmonary drug-susceptible tuberculosis compared three 4-month rifapen…
A new clinical trial explores how different doses of rifapentine affect treatment success and safety for patients with drug-susceptible tube…
Shorter rifamycin-containing regimens show comparable efficacy to longer isoniazid monotherapy for latent tuberculosis infection
Shorter drug plans may help children finish tuberculosis treatments
This meta-analysis evaluated shorter rifamycin-containing regimens against a nine-month isoniazid course in children with latent tuberculosi…
New data suggests shorter treatment plans for latent tuberculosis can help children complete their medication without increasing the risk of…
Multidrug-resistant tuberculosis prevalence is 5.2% among patients with bacteriologically confirmed cases in Cameroon
Identifying key risks for drug resistant tuberculosis infections in Cameroon
This meta-analysis of 28 studies involving 9,931 patients identifies a 5.2% pooled prevalence of multidrug-resistant tuberculosis (MDR-TB) i…
New data shows that past infections and lifestyle factors like alcohol use can increase the risk of developing hard-to-treat tuberculosis.
Questions about Pulmonary Tuberculosis
What factors help differentiate non-tuberculous mycobacterial disease from tuberculosis in patients?
NTM lung disease is more likely in older patients with bronchiectasis, COPD, or diabetes, and often shows thin-walled cavities on CT; TB-IGRA is usually negative in NTM.
Full answer →How well does a combined radiomics model distinguish tuberculosis from other lung lesions?
A combined radiomics model shows good accuracy (AP 0.85-0.91) for distinguishing tuberculosis from other lung lesions on CT, though performance drops in temporal validation (AP 0.62).
Full answer →Is the rate of confirmed pulmonary tuberculosis cases dropping in Hunan Province?
Data from Hunan Province shows the rate of confirmed pulmonary tuberculosis cases dropped by an average of 2.2% annually between 2009 and 2023, though the decline slowed after 2017.
Full answer →